WNT4 Protein, wingless-related MMTV integration site 4


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Official Full Name wingless-related MMTV integration site 4
Background The evolutionarily conserved WNT (Wingless-type MMTV integration site family) signaling pathway has diverse roles in governing cell fate, proliferation, migration, polarity and death. WNT signaling controls development and is important for embryogenesis a
Synonyms WNT4; wingless-related MMTV integration site 4; protein Wnt-4; signal molecule; Wnt-4; MGC123964; SERKAL
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT4-1891H Recombinant Human WNT4 protein, His-tagged E.coli His
    Human WNT4-294HCL Recombinant Human WNT4 293 Cell Lysate HEK293 N/A
    Human WNT4-3740H Recombinant Human WNT4, GST-tagged E.coli GST
    Human WNT4-413H Recombinant Human WNT4 Protein, GST/His-tagged E.coli GST/His
    Human WNT4-516H Recombinant Human Wingless-Type MMTV Integration Site Family, Member 4 CHO N/A
    Mouse WNT4-18572M Recombinant Mouse WNT4 Protein Mammalian Cell His
    Mouse Wnt4-622M Recombinant Mouse Wnt4 CHO N/A
    Rat WNT4-6599R Recombinant Rat WNT4 Protein Mammalian Cell His
    Chicken WNT4-6347C Recombinant Chicken WNT4 Mammalian Cell His

    WNT4 involved in several pathways and played different roles in them. We selected most pathways WNT4 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway PRKACAB; RAC3B; APC; TCF7L2; CAMK2B; PORCNL; WNT2BB; FRAT2; FBXW11B; NFATC3
    Hedgehog signaling pathway ZIC2; SAP18; SKIA; SUFU; PRKACA; FBXW11; CSNK1G2B; WNT9A; WNT8A; WNT2BB
    Hippo signaling pathway BIRC2; FZD7; BMP8A; BMP7; PPP2CB; PPP2R1A; PPP1CC; PPP2R2A; YWHAB; CCND1
    Signaling pathways regulating pluripotency of stem cells PIK3CG; LHX5; WNT9B; WNT4; BMPR1B; GRB2; PIK3R1; SMAD3; FZD8; BMPR1A
    Thyroid hormone signaling pathway AKT1; MED14; PLCD4; ITGB3; KAT2B; SLC2A1; AKT2; SLC16A10; PIK3R1; PLCG1
    HTLV-I infection VDAC1; EP300; SMAD2; NFATC4; TRP53INP1; TSPO; NRAS; TCF3; WNT2; HLA-DQA1
    Pathways in cancer PIK3R3; TP53; WNT1; CKS2; FGF4; GLI1; PRKCG; VHL; MAP2K1; Shh
    Proteoglycans in cancer PXN; Ctsl; CBLB; GAB1; WNT10B; VEGFA; RDX; RPS6; WNT8A; CAMK2A
    Basal cell carcinoma WNT5B; TP53; STK36; WNT2; GLI1; FZD9; WNT10B; WNT1; WNT4; WNT9B

    WNT4 has several biochemical functions, for example, frizzled binding, receptor agonist activity, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT4 itself. We selected most functions WNT4 had, and list some proteins which have the same functions with WNT4. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding WNT9A; RNF43; LRP6; DVL1; WNT5A; WNT1; WNT10B; WNT3; BAMBI; WNT3A
    receptor agonist activity GREM1; WNT8A; VEGFA; WNT10B; WNT2; CXCL13; WNT7A; NODAL; WNT3A; WNT4
    transcription corepressor activity BASP1; MECP2; BRD7; GMNN; CRYM; NR0B2; TBL1XR1; SIRT6; SKIL; SMARCA4

    WNT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT4.


    Morizane, R; Monkawa, T; et al. Kidney Specific Protein-Positive Cells Derived from Embryonic Stem Cells Reproduce Tubular Structures In Vitro and Differentiate into Renal Tubular Cells. PLOS ONE 8:-(2013).
    Murugan, S; Shan, JD; et al. WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis. EXPERIMENTAL CELL RESEARCH 318:1134-1145(2012).


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