WNT8A Protein, wingless-type MMTV integration site family, member 8A

WNT8A

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WNT8A

Official Full Name wingless-type MMTV integration site family, member 8A
Background The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.
Synonyms WNT8A; wingless-type MMTV integration site family, member 8A; protein Wnt-8a; WNT8D; protein Wnt-8d
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • CHO
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT8A-209H Recombinant Human WNT8A, StrepII-tagged Human Cell Strep II
    Human WNT8A-254H Recombinant Human WNT8A protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human WNT8A-287HCL Recombinant Human WNT8A 293 Cell Lysate HEK293 N/A
    Mouse Wnt8a-619M Recombinant Mouse Wnt8a CHO N/A
    Chicken WNT8A-7079C Recombinant Chicken WNT8A Mammalian Cell His
    Zebrafish WNT8A-8586Z Recombinant Zebrafish WNT8A Mammalian Cell His

    WNT8A involved in several pathways and played different roles in them. We selected most pathways WNT8A participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT8A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway MAPK8; FZD3A; TBL1X; MAPK10; CUL1; PPP3CC; CAMK2A; PLCB3; DKK1; SKP1
    Hedgehog signaling pathway WNT3A; SHHA; FBXW11; DHH; WNT9B; WNT2; CSNK1G2A; FBXW11A; RAB23; PRKACB
    Hippo signaling pathway WNT2B; FZD6; YWHAB; AREG; DVL3; WWTR1; CCND2; SERPINE1; BMPR1A; PARD6A
    Signaling pathways regulating pluripotency of stem cells INHBA; MYF5; PCGF3; PIK3R5; LIF; PIK3CA; PIK3CB; FGFR3; WNT7A; HOXB1
    Melanogenesis CAMK2D; GNAI3; FZD8B; FZD10; WNT4; HRAS; PRKACG; CALM1; GNA15.4; HRASA
    HTLV-I infection CD3E; CALR; PIK3R1; PTTG1; ATF4; MAP3K14; MAP3K3; SRF; HLA-DRA; MYBL1
    Pathways in cancer GNAI3; GNB3; WNT10B; CXCR4; TRAF6; BCL2L1; CXCL12; FLT3; PAX8; WNT4
    Proteoglycans in cancer FZD10; HIF1A; HOXD10; RPS6KB2; PIK3R3; PLCE1; WNT1; FZD5; ITGB3; PTK2
    Basal cell carcinoma WNT6; FZD8; SETD6; WNT16; WNT7A; APC; HHIP; WNT2; WNT11; AXIN1

    WNT8A has several biochemical functions, for example, frizzled binding, receptor agonist activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT8A itself. We selected most functions WNT8A had, and list some proteins which have the same functions with WNT8A. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding WNT10B; CTHRC1; WNT6; DVL1B; WNT11R; WNT9A; DVL2; ZNRF3; WNT7B; WNT3
    receptor agonist activity WNT10B; VEGFA; WNT7A; GREM1; CXCL13; WNT4; WNT5A; GAS6; WNT3; WNT2

    WNT8A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT8A here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT8A.

    Choi, SC; Lee, H; et al. Cyclosporin A Induces Cardiac Differentiation but Inhibits Hemato-Endothelial Differentiation of P19 Cells. PLOS ONE 10:-(2015).
    Stanganello, E; Hagemann, AIH; et al. Filopodia-based Wnt transport during vertebrate tissue patterning. NATURE COMMUNICATIONS 6:-(2015).

    WNT

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