wnt8a
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  • Official Full Name
  • wingless-type MMTV integration site family, member 8A
  • Background
  • The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.
  • Synonyms
  • WNT8A; wingless-type MMTV integration site family, member 8A; protein Wnt-8a; WNT8D; protein Wnt-8d
Cat.#:WNT8A-209HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human WNT8A, StrepII-tagged
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Cat.#:WNT8A-254HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human WNT8A protein, MYC/DDK-tagged
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Cat.#:Wnt8a-619MTag:
Source (Host):CHO CellsSpecies:Mouse
Product nameRecombinant Mouse Wnt8a
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Cat.#:WNT8A-7079CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WNT8A
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Cat.#:WNT8A-8586ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WNT8A
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Cat.#:WNT8A-287HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WNT8A 293 Cell Lysate
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Involved Pathway

WNT8A involved in several pathways and played different roles in them. We selected most pathways WNT8A participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT8A were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
WNT7A; SFRP4; TBL1XR1; SERPINF1; PPP3CCB; RAC1B; CAMK2G1; PLCB4; CAMK2D; FZD5
Hedgehog signaling pathway
SUFU; WNT8B; CSNK1DA; IHHB; GSK3B; GLI2; PRKACBB; SKIA; CSNK1G1; WNT11
Hippo signaling pathway
FZD2; MOB1A; PARD6A; APC2; STK3; PPP2R2A; LATS1; ACTG1; ID1; PPP2CA
Signaling pathways regulating pluripotency of stem cells
AXIN2; AKT1; INHBC; ACVR1; ID4; GSK3B; ID1; INHBE; WNT7A; BMPR1A
Melanogenesis
KITA; NRAS; WNT8B; WNT11R; CALM3A; PRKCG; RAF1B; GNAI1; GNA15.4; WNT7AA
HTLV-I infection
LTA; TSPO; HLA-DQB1; AKT2; PIK3R5; WNT16; ANAPC2; NFATC3; HLA-DRB4; PDGFRA
Pathways in cancer
RAD51; MAX; FGFR3; PTEN; SPI1; NCOA4; FGFR2; KIT; FGF3; MDM2
Proteoglycans in cancer
FZD10; PPP1CB; PIK3R1; RPS6; WNT11; LUM; THBS1; WNT8B; ROCK1; PPP1R12B
Basal cell carcinoma
AXIN2; AXIN1; TCF7L2; SUFU; FZD3; DVL1; BMP2; STK36; WNT5B; WNT7A

Protein Function

WNT8A has several biochemical functions, for example, frizzled binding, receptor agonist activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT8A itself. We selected most functions WNT8A had, and list some proteins which have the same functions with WNT8A. You can find most of the proteins on our site.
Function
Related Protein
Function frizzled binding
Related Protein WNT3; WNT8B; WNT4A; BAMBI; WNT7B; ZNRF3; WNT6; DVL3; WNT2B; WNT2
Function receptor agonist activity
Related Protein WNT3; WNT10B; WNT1; GREM1; VEGFA; WNT4; WNT3A; GAS6; WNT7A; WNT8A

WNT8A Related Articles

Choi, SC; Lee, H; et al. Cyclosporin A Induces Cardiac Differentiation but Inhibits Hemato-Endothelial Differentiation of P19 Cells. PLOS ONE 10:-(2015).
Stanganello, E; Hagemann, AIH; et al. Filopodia-based Wnt transport during vertebrate tissue patterning. NATURE COMMUNICATIONS 6:-(2015).

WNT8A Related Gene Family

WNT