|Official Full Name||wingless-type MMTV integration site family, member 8A|
|Background||The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.|
|Synonyms||WNT8A; wingless-type MMTV integration site family, member 8A; protein Wnt-8a; WNT8D; protein Wnt-8d|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
WNT8A involved in several pathways and played different roles in them. We selected most pathways WNT8A participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT8A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Wnt signaling pathway||MAPK8; FZD3A; TBL1X; MAPK10; CUL1; PPP3CC; CAMK2A; PLCB3; DKK1; SKP1|
|Hedgehog signaling pathway||WNT3A; SHHA; FBXW11; DHH; WNT9B; WNT2; CSNK1G2A; FBXW11A; RAB23; PRKACB|
|Hippo signaling pathway||WNT2B; FZD6; YWHAB; AREG; DVL3; WWTR1; CCND2; SERPINE1; BMPR1A; PARD6A|
|Signaling pathways regulating pluripotency of stem cells||INHBA; MYF5; PCGF3; PIK3R5; LIF; PIK3CA; PIK3CB; FGFR3; WNT7A; HOXB1|
|Melanogenesis||CAMK2D; GNAI3; FZD8B; FZD10; WNT4; HRAS; PRKACG; CALM1; GNA15.4; HRASA|
|HTLV-I infection||CD3E; CALR; PIK3R1; PTTG1; ATF4; MAP3K14; MAP3K3; SRF; HLA-DRA; MYBL1|
|Pathways in cancer||GNAI3; GNB3; WNT10B; CXCR4; TRAF6; BCL2L1; CXCL12; FLT3; PAX8; WNT4|
|Proteoglycans in cancer||FZD10; HIF1A; HOXD10; RPS6KB2; PIK3R3; PLCE1; WNT1; FZD5; ITGB3; PTK2|
|Basal cell carcinoma||WNT6; FZD8; SETD6; WNT16; WNT7A; APC; HHIP; WNT2; WNT11; AXIN1|
WNT8A has several biochemical functions, for example, frizzled binding, receptor agonist activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT8A itself. We selected most functions WNT8A had, and list some proteins which have the same functions with WNT8A. You can find most of the proteins on our site.
|frizzled binding||WNT10B; CTHRC1; WNT6; DVL1B; WNT11R; WNT9A; DVL2; ZNRF3; WNT7B; WNT3|
|receptor agonist activity||WNT10B; VEGFA; WNT7A; GREM1; CXCL13; WNT4; WNT5A; GAS6; WNT3; WNT2|
WNT8A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT8A here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT8A.