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YY1

  • Official Full Name

    YY1 transcription factor

  • Overview

    YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]
  • Synonyms

    YY1; YY1 transcription factor; DELTA; NF-E1; UCRBP; INO80S; YIN-YANG-1; transcriptional repressor protein YY1; YY-1; Yin and Yang 1 protein; INO80 complex subunit S; delta transcription factor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Insect cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human YY1-630H Recombinant Human YY1 Protein, His-tagged E.coli His
Human YY1-31565TH Recombinant Human YY1 Wheat Germ N/A 100 amino acids
Human YY1-2674H Recombinant Human YY1, His-tagged E.coli His
Human YY1-16H Recombinant Human YY1, His-tagged E.coli His 1-414aa
Human YY1-632H Recombinant Human YY1 transcription factor, His-tagged E.coli His
Human YY1-599H Recombinant Human YY1, FLAG-tagged E.coli Flag
Human YY1-228HCL Recombinant Human YY1 293 Cell Lysate HEK293 N/A
Human YY1-12HFL Recombinant Full Length Human YY1 Protein, N-Flag-tagged Insect cells N-Flag
Mouse YY1-18688M Recombinant Mouse YY1 Protein Mammalian Cell His
Mouse YY1-10272M-B Recombinant Mouse YY1 Protein Pre-coupled Magnetic Beads HEK293
Mouse YY1-10272M Recombinant Mouse YY1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken YY1-2873C Recombinant Chicken YY1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • YY1 Related Articles

YY1 involved in several pathways and played different roles in them. We selected most pathways YY1 participated on our site, such as DNA Damage Recognition in GG-NER, DNA Repair, Delta-Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA Damage Recognition in GG-NERACTL6A;COPS7B;COPS5;GPS1;COPS4;COPS2;INO80B;INO80E;COPS3
DNA RepairPAXIP1;COPS8;TDP1;DTL;SMARCA5;COPS5;CHEK2;PPP4R2B;KIAA1530
Delta-Notch Signaling PathwayADAM10A;JAG1;ASCL1;RING1;HEY1;ZFPM1;TLE1;TUBB3;SMAD3B
E2F transcription factor networkCEBPA;RYBP;YY1;TRIM28;CES3;HIC1;E2F4;CES1;CBX5
Global Genome Nucleotide Excision Repair (GG-NER)COPS2;COPS5;TFPT;INO80C;PIAS3;ACTR5;CHD1L;COPS6;YY1A
Notch signaling pathwayDLB;HDAC1;NUMB;CNTN6;DLL1;PTCRA;NOTCH1B;MFAP5;PSEN2
Notch-mediated HES/HEY networkHES6;MYB;YY1;RCAN1;GATA1;HEY1;ASCL1;CTBP1;GATA6
Nucleotide Excision RepairPPIE;RFC3;MCRS1;COPS6;COPS8;GTF2H1;GTF2H3;INO80;GTF2H3-2

YY1 has several biochemical functions, for example, DNA binding, RNA binding, SMAD binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YY1 itself. We selected most functions YY1 had, and list some proteins which have the same functions with YY1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingGM239;H2AFB3;ZBTB7A;SUB1B;RELA;ZNF280A;HOXC13A;ZFP35;ZNF367
RNA bindingNCL;ETF1;CNOT8;SRSF3;DDX11;CELF5;SURF6;DDX43;CPSF1
SMAD bindingEID2;COL5A2;EP300;PML;MAGI2;TOB1;FLNA;SMURF2;HMGA2
enhancer sequence-specific DNA bindingTBX19;MYT1;ATF2;KLF6A;HMGB2;TWIST1B;GATA5;SOX11;LDB1
four-way junction DNA bindingMEN1;HMGB2;RAD51;RAD51L3;RAD51L1;HMGB3;HMGB1;DMC1;YY1
histone deacetylase bindingDDX20;PKN1;MYOCD;SRF;HDAC10;SIRT2;HDAC4;ANKRA2;HOXA10
protein bindingITGB1BP2;PDCD5;KIF7;AKAP12;BAP1;RLN3;MAPKAPK5;TBX6;MAPK8IP3
transcription coactivator activityTAF5L;PIAS1;ELF3;BIRC2;TAF7;RUNX1;CARM1;MED20;NPAT
transcription corepressor activityLHX1;NFIL3;CREG1;BATF3;KCTD1;SSX4;ZNF136;BRD7;MECP2
transcription factor activity, sequence-specific DNA bindingRB1;FOXI3B;HOXB5B;ZNF643;KLF11;HSF5;TADA2A;EGR2B;NFYB
transcription regulatory region DNA bindingNCOR1;ATMIN;AHR;TA;HNF4A;ATF4;WNT1;LEF1;TRP63
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingPROX2;HOXA2;HSF1;SREBF2;GFI1;TFAP2A;MXD1;SKIL;KLF16
zinc ion bindingCA15A;RNF182;MARCH8;CPN1;MARCH4;CUL9;ZNF207;MAN2A1;TRIM35-1

YY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of YY1.

ACTL6A; E1A; ARRB1; INO80; RUVBL2

Kang, W; Tong, JHM; et al. Yin Yang 1 contributes to gastric carcinogenesis and its nuclear expression correlates with shorter survival in patients with early stage gastric adenocarcinoma. JOURNAL OF TRANSLATIONAL MEDICINE 12:-(2014).
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