YY1

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YY1

Official Full Name YY1 transcription factor
Background YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]
Synonyms YY1; YY1 transcription factor; DELTA; NF-E1; UCRBP; INO80S; YIN-YANG-1; transcriptional repressor protein YY1; YY-1; Yin and Yang 1 protein; INO80 complex subunit S; delta transcription factor;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Flag
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human YY1-16H Recombinant Human YY1, His-tagged E.coli His
    Human YY1-228HCL Recombinant Human YY1 293 Cell Lysate HEK293 N/A
    Human YY1-2674H Recombinant Human YY1, His-tagged E.coli His
    Human YY1-31565TH Recombinant Human YY1 Wheat Germ N/A
    Human YY1-599H Recombinant Human YY1, FLAG-tagged E.coli Flag
    Human YY1-630H Recombinant Human YY1 Protein, His-tagged E.coli His
    Human YY1-632H Recombinant Human YY1 transcription factor, His-tagged E.coli His
    Mouse YY1-18688M Recombinant Mouse YY1 Protein Mammalian Cell His
    Chicken YY1-2873C Recombinant Chicken YY1 Mammalian Cell His

    YY1 involved in several pathways and played different roles in them. We selected most pathways YY1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with YY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    DNA Damage Recognition in GG-NER COPS2; GPS1; INO80C; DDB1; CETN2; NFRKB; PARP2; YY1A; COPS7A; TFPT
    DNA Repair RAD17; KIAA0146; TOPBP1; EYA4; COPS7A; BABAM1; FUZ; TDP2B; APITD1; TCEA1
    Delta-Notch Signaling Pathway APPA; TLE1; CNTFR; YY1A; ASCL1; CNTN1B; HIVEP3; ASCL1A; HES6; JAG2
    E2F transcription factor network CBX5; CES1; HIC1; HBP1; CES3; E2F6; MYBL2; SMARCA2; DHFR; TRIM28
    Global Genome Nucleotide Excision Repair (GG-NER) INO80C; COPS4; CHD1L; TFPT; COPS5; ACTR5; COPS7A; GPS1; COPS7B; INO80E
    Notch signaling pathway RBPJB; NOTCH3; DVL3A; DLL1; PSENEN; DTX3; DLB; NOTCH2; CIR1; PTCRA
    Notch-mediated HES/HEY network HES6; MYB; MYOD1; HEY1; CTBP1; RCAN1; BGLAP; GATA1; TLE1; YY1
    Nucleotide Excision Repair GTF2H2; XPC; GTF2H2C_2; INO80; COPS8; ERCC5; ERCC3; LIG1; RPA3; POLD2

    YY1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by YY1 itself. We selected most functions YY1 had, and list some proteins which have the same functions with YY1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding POU3F3; ZNF738; SWAP70; TERFA; ZNF652; ARID3C; CERS3B; HIST1H4K; PPARGC1A; STRBP
    RNA binding YY1; UNC50; TEP1; DUSP11; PCBP2; SARNP; KIN; RPL30; ZNF74; NUFIP2
    SMAD binding SMURF2; COL5A2; HMGA2; FKBP1A; DAB2; BMPR1A; SKI; YY1; COL3A1; ACVR1
    enhancer sequence-specific DNA binding TWIST1B; GATA1; ISL1; SOX11; TBX19; KLF7B; GATA3; KLF6A; TFAP2B; LDB1
    four-way junction DNA binding RAD51L3; HMGB2; YY1; RAD51; RAD51L1; HMGB1; DMC1; HMGB3; MEN1
    histone deacetylase binding NIPBL; HIST1H1B; RELA; NUDT21; MEF2B; MAGEA1; HEY2; MAPK8; HDAC3; NCOR2
    protein binding EHD1; PPM1F; IPO4; ASF1A; BRD4; PLXNC1; SLC5A1; ISCA2; AKAP13; KRT4
    transcription coactivator activity STIL; GTF2A2; MED6; SUPT7L; NCOA2; PSMC3; TFDP1B; TFDP1; CDK7; NEUROD1
    transcription corepressor activity NRIP1; DDIT3; JUB; MYBBP1A; ALX1; TAF9B; PEX14; NCOR1; ATF5; HSF4
    transcription factor activity, sequence-specific DNA binding NFE2; NR2F6B; MYCS; VAV1; DRAP1; SMAD5; OTX1A; STAT2; NFYA; ZIK1
    transcription regulatory region DNA binding ZFP513; SMAD3; RNF10; ATF4; PROX1; ZFP746; CCNT1; HIVEP2A; ATMIN; CTNNB1
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding NKX3-2; HSF1; MYPOP; NR2E1; TBX15; BCL11A; PITX2; HMGA2; SP3; RCOR1
    zinc ion binding TRIM35-23; ZNF3; FBXO40; BRF1; RNF125; PDLIM4; KDM5A; XIRP2; ZNF257; BAZ1B

    YY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of YY1.

    ACTL6A; E1A; ARRB1; INO80; RUVBL2

    Hasanali, ZS; Epner, EM; et al. Vorinostat Downregulates CD30 and Decreases Brentuximab Vedotin Efficacy in Human Lymphocytes. MOLECULAR CANCER THERAPEUTICS 13:2784-2792(2014).
    Kang, W; Tong, JHM; et al. Yin Yang 1 contributes to gastric carcinogenesis and its nuclear expression correlates with shorter survival in patients with early stage gastric adenocarcinoma. JOURNAL OF TRANSLATIONAL MEDICINE 12:-(2014).

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