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ZFP36L1

  • Official Full Name

    zinc finger protein 36, C3H type-like 1

  • Overview

    This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    ZFP36L1; zinc finger protein 36, C3H type-like 1; BRF1, zinc finger protein, C3H type, 36 like 1; zinc finger protein 36, C3H1 type-like 1; Berg36; cMG1; ERF1; RNF162B; TIS11B; EGF-response factor 1; butyrate response factor 1; early response factor Berg;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ZFP36L1-090H Recombinant Human ZFP36L1 Protein, GST-HIS-tagged E.coli GST/His
Human ZFP36L1-3802H Recombinant Human ZFP36L1, GST-tagged E.coli GST 1-338aa
Human ZFP36L1-3801H Recombinant Human ZFP36L1 protein, GST-tagged Wheat Germ GST
Human ZFP36L1-180HCL Recombinant Human ZFP36L1 293 Cell Lysate HEK293 N/A
Mouse ZFP36L1-18910M Recombinant Mouse ZFP36L1 Protein Mammalian Cell His
Mouse ZFP36L1-10346M-B Recombinant Mouse ZFP36L1 Protein Pre-coupled Magnetic Beads HEK293
Mouse ZFP36L1-10346M Recombinant Mouse ZFP36L1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ZFP36L1-6682R Recombinant Rat ZFP36L1 Protein Mammalian Cell His
Rat ZFP36L1-6329R-B Recombinant Rat ZFP36L1 Protein Pre-coupled Magnetic Beads HEK293
Rat ZFP36L1-6329R Recombinant Rat ZFP36L1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ZFP36L1 involved in several pathways and played different roles in them. We selected most pathways ZFP36L1 participated on our site, such as Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Gene Expression, Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFP36L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNAZFP36L1;EXOSC8;ZFP36L1A;ZFP36L1B;DCP2;MAPKAPK2B
Gene ExpressionZFP28;DCP2;SRSF11;POU2F1;ZNF614;ZNF184;TRIM28;NRBF2B;TAF1L
Regulation of mRNA stability by proteins that bind AU-rich elementsSETA;ANP32A;KHSRP;ZFP36L1A;HNRNPD;SET;ZFP36L1B;ELAVL1;TNPO1
Validated targets of C-MYC transcriptional repressionCLU;SFXN3;MXD4;TMEM126A;S100A7;TMEFF2;CSDE1;DNTT;GFI1

ZFP36L1 has several biochemical functions, for example, AU-rich element binding, DNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFP36L1 itself. We selected most functions ZFP36L1 had, and list some proteins which have the same functions with ZFP36L1. You can find most of the proteins on our site.

Function Related Protein
AU-rich element bindingCPSF5;EXOSC9;EXOSC4;TIA1;ZFP36L1;ELAVL1;EXOSC7;ZFP36L3;ELAVL4
DNA bindingCDKN2A;KCNIP3;ZNF254;DR1;ORC3;HOXC1A;ZMYM4;SUPV3L1;POLA2
mRNA bindingPURB;PIWIL1;CPSF5;CROP;XPO5;DOM3Z;MRPS7;FXR2;RBM38
metal ion bindingFOXP1;AGFG2;ZNF781;DNAJA2;ANKMY2;ZNF688;ZSCAN23;ZNF434;TRIM67
poly(A) RNA bindingAPEX1;U2SURP;MANF;NSBP1;CSTF2T;NUSAP1;RBM5;ARL6IP4;FLYWCH2
protein bindingATG14;EXOSC7;TBL1X;LRRIQ3;RFWD2;PIDD1;KCNE3;SYT4;ZBTB49
transcription factor activity, sequence-specific DNA bindingZNF256;RFXAP;CITED2;SMAD3A;ZFP161;FOXO3B;KAT7A;ZNF207;RB1

ZFP36L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFP36L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFP36L1.

MAPK14; TERF1; PAFAH1B2; SF1; mexB; yrrO; TFAP2C; ACD; TINF2; POT1; YWHAZ

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