|Official Full Name||zinc finger protein 36, C3H type-like 1|
|Background||This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||ZFP36L1; zinc finger protein 36, C3H type-like 1; BRF1, zinc finger protein, C3H type, 36 like 1; zinc finger protein 36, C3H1 type-like 1; Berg36; cMG1; ERF1; RNF162B; TIS11B; EGF-response factor 1; butyrate response factor 1; early response factor Berg|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ZFP36L1 involved in several pathways and played different roles in them. We selected most pathways ZFP36L1 participated on our site, such as Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Gene Expression, Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFP36L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA||DCP2; ZFP36L1A; ZFP36L1B; MAPKAPK2B; ZFP36L1; EXOSC8|
|Gene Expression||MAPKAPK2B; ZNF23; ZNF287; ZNF669; ZNF596; METTL3; ZNF443; CSTF1; NR2E3; ZNF771|
|Regulation of mRNA stability by proteins that bind AU-rich elements||ZFP36L1; SETA; ZFP36L1B; HUG; ELAVL1; SETB; ZFP36L1A; ANP32A; TNPO1; KHSRP|
|Validated targets of C-MYC transcriptional repression||DNTT; LGALS1; NDRG1; CLU; MXD4; CSDE1; TMEFF2; TMEM126A; GFI1; ZFP36L1|
ZFP36L1 has several biochemical functions, for example, AU-rich element binding, DNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFP36L1 itself. We selected most functions ZFP36L1 had, and list some proteins which have the same functions with ZFP36L1. You can find most of the proteins on our site.
|AU-rich element binding||ZFP36; TIA1; TIAL1; CPSF5; ZFP36L1; APOBEC1; NUDT21; ELAVL1; EXOSC9; ELAVL4|
|DNA binding||PBX1A; AHCTF1; PAX3A; ZFP191; TMPO; FOXQ1A; IRX1A; NR4A3; RBFOX3; SP8|
|mRNA binding||HSP26; SRRM4; PCF11; CSTF2; MECP2; CSTF2T; HNRPLL; NUDT21; CSTF3; TPR|
|metal ion binding||SP7; TSNAX; PDE1C; ADAMTS16; GNAS; ZNF295; SMAD5; RASAL1; DNAJA4; PHF20B|
|poly(A) RNA binding||CSTF1; RPL28; RPS23; GOT2; SRSF11; HIST4H4; SLC25A11; CLTC; PRPF38B; RPGR|
|protein binding||WBP1; MAP2; FOXG1; TXNRD3; USP19; GAGE1; TMBIM6; CBX3; FBXL5; ASGR1|
|transcription factor activity, sequence-specific DNA binding||CREB3L3A; TBX4; SIM1; GATA2B; HOXD3A; KDM1A; TCF7L1A; ZFP287; LEF1; PBX1B|
ZFP36L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFP36L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFP36L1.
MAPK14; TERF1; PAFAH1B2; SF1; mexB; yrrO; TFAP2C; ACD; TINF2; POT1; YWHAZ