ZFP36L1 Protein, zinc finger protein 36, C3H type-like 1


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Official Full Name zinc finger protein 36, C3H type-like 1
Background This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms ZFP36L1; zinc finger protein 36, C3H type-like 1; BRF1, zinc finger protein, C3H type, 36 like 1; zinc finger protein 36, C3H1 type-like 1; Berg36; cMG1; ERF1; RNF162B; TIS11B; EGF-response factor 1; butyrate response factor 1; early response factor Berg
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ZFP36L1-090H Recombinant Human ZFP36L1 Protein, GST-HIS-tagged E.coli GST/His
    Human ZFP36L1-180HCL Recombinant Human ZFP36L1 293 Cell Lysate HEK293 N/A
    Human ZFP36L1-3801H Recombinant Human ZFP36L1 protein, GST-tagged Wheat Germ GST
    Human ZFP36L1-3802H Recombinant Human ZFP36L1, GST-tagged E.coli GST
    Mouse ZFP36L1-18910M Recombinant Mouse ZFP36L1 Protein Mammalian Cell His
    Rat ZFP36L1-6682R Recombinant Rat ZFP36L1 Protein Mammalian Cell His

    ZFP36L1 involved in several pathways and played different roles in them. We selected most pathways ZFP36L1 participated on our site, such as Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Gene Expression, Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFP36L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA DCP2; ZFP36L1A; ZFP36L1B; MAPKAPK2B; ZFP36L1; EXOSC8
    Gene Expression MAPKAPK2B; ZNF23; ZNF287; ZNF669; ZNF596; METTL3; ZNF443; CSTF1; NR2E3; ZNF771
    Regulation of mRNA stability by proteins that bind AU-rich elements ZFP36L1; SETA; ZFP36L1B; HUG; ELAVL1; SETB; ZFP36L1A; ANP32A; TNPO1; KHSRP
    Validated targets of C-MYC transcriptional repression DNTT; LGALS1; NDRG1; CLU; MXD4; CSDE1; TMEFF2; TMEM126A; GFI1; ZFP36L1

    ZFP36L1 has several biochemical functions, for example, AU-rich element binding, DNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFP36L1 itself. We selected most functions ZFP36L1 had, and list some proteins which have the same functions with ZFP36L1. You can find most of the proteins on our site.

    Function Related Protein
    AU-rich element binding ZFP36; TIA1; TIAL1; CPSF5; ZFP36L1; APOBEC1; NUDT21; ELAVL1; EXOSC9; ELAVL4
    DNA binding PBX1A; AHCTF1; PAX3A; ZFP191; TMPO; FOXQ1A; IRX1A; NR4A3; RBFOX3; SP8
    mRNA binding HSP26; SRRM4; PCF11; CSTF2; MECP2; CSTF2T; HNRPLL; NUDT21; CSTF3; TPR
    metal ion binding SP7; TSNAX; PDE1C; ADAMTS16; GNAS; ZNF295; SMAD5; RASAL1; DNAJA4; PHF20B
    poly(A) RNA binding CSTF1; RPL28; RPS23; GOT2; SRSF11; HIST4H4; SLC25A11; CLTC; PRPF38B; RPGR
    protein binding WBP1; MAP2; FOXG1; TXNRD3; USP19; GAGE1; TMBIM6; CBX3; FBXL5; ASGR1
    transcription factor activity, sequence-specific DNA binding CREB3L3A; TBX4; SIM1; GATA2B; HOXD3A; KDM1A; TCF7L1A; ZFP287; LEF1; PBX1B

    ZFP36L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFP36L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFP36L1.

    MAPK14; TERF1; PAFAH1B2; SF1; mexB; yrrO; TFAP2C; ACD; TINF2; POT1; YWHAZ

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