zhx3
Share
  • Official Full Name
  • zinc fingers and homeoboxes 3
  • Background
  • This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.
  • Synonyms
  • ZHX3; zinc fingers and homeoboxes 3; TIX1, triple homeobox 1; zinc fingers and homeoboxes protein 3; KIAA0395; triple homeobox 1; triple homeobox protein 1; zinc finger and homeodomain protein 3; TIX1
Cat.#:ZHX3-6707RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ZHX3 Protein
+Inquiry
Cat.#:ZHX3-5293RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ZHX3 Protein, His-tagged
+Inquiry
Cat.#:ZHX3-9847ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ZHX3
+Inquiry
Cat.#:ZHX3-1983HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ZHX3 cell lysate
+Inquiry

Protein Function

ZHX3 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX3 itself. We selected most functions ZHX3 had, and list some proteins which have the same functions with ZHX3. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP41; CCDC79; ZMAT2; NFIXB; ZNF84; IRX4B; SUB1B; RHOXF1; CDX1B; TOPORS
Function metal ion binding
Related Protein ZFP36L1B; CELA1; PHF23B; PRDM10; CYP8B1; RXRBA; TRIM35-34; RNF148; OVOL3; ADSSL
Function protein binding
Related Protein TRA2B; PMM2; UBA1; DDX19B; STAT5B; CEP350; EXOSC5; FANCD2; NIPSNAP1; MSN
Function protein heterodimerization activity
Related Protein LIMK1; SUPT3H; SDCBP2; PDSS2; ZHX3; ZBTB1; TPD52L1; MAFA; HIST1H4B; SPNA1
Function protein homodimerization activity
Related Protein CD4; SYT10; EIF2AK3; PVRL1; ADH5; EIF2AK1; SUMF1; TGFB1; BAX; LMLN
Function transcription corepressor activity
Related Protein TLE2; SRSF2; DDIT3; NPAT; MSC; TRIM22; NFKBIL2; HIRA; ASXL1; SKOR2
Function transcription factor activity, sequence-specific DNA binding
Related Protein POU2F2; POU6F1; SOX3; ZNF544; MTA2; Ar; CDX1B; NEUROG1; PHF5A; HIST1H2AH

Interacting Protein

ZHX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX3.
NLK; ATXN1; q8ckl9_yerpe; q9wmx2-pro_0000037548; mdm2_human_probe

ZHX3 Related Articles

Lee, JH; Nam, H; et al. Upregulation of GM-CSF by TGF-beta 1 in epithelial mesenchymal transition of human HERS/ERM cells. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 50:399-405(2014).
Chaudhry, P; Fabi, F; et al. Prostate apoptosis response-4 mediates TGF-beta-induced epithelial-to-mesenchymal transition. CELL DEATH & DISEASE 5:-(2014).