|Official Full Name||zinc finger, matrin-type 3|
|Background||This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.|
|Synonyms||ZMAT3; zinc finger, matrin-type 3; zinc finger matrin-type protein 3; FLJ12296; MGC10613; PAG608; WIG 1; WIG1; FLJ31683; OTTHUMP00000211906; OTTHUMP00000211907; p53 activated gene 608; p53 inducible zinc finger protein; p53 target zinc finger protein; p53-activated gene 608 protein; PAG 608; WIG 1/PAG608 protein; WIG1/PAG608 protein; Zinc finger matrin type 3; Zinc finger protein WIG 1; Zinc finger protein WIG-1; Zinc finger protein WIG1; ZMAT 3; ZMAT3_HUMAN; WIG-1/PAG608 protein; zinc finger, matrin type 3; WIG-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ZMAT3 involved in several pathways and played different roles in them. We selected most pathways ZMAT3 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZMAT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|p signaling pathway||CASP9; CD82A; CASP3B; Casp3; CASP8; BID; PIDD1; BBC3; THBS1; BAX|
ZMAT3 has several biochemical functions, for example, p53 binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZMAT3 itself. We selected most functions ZMAT3 had, and list some proteins which have the same functions with ZMAT3. You can find most of the proteins on our site.
|p53 binding||BCL2L12; TRP63; PLK3; RCHY1; ANKRD1; KDM1A; PSME3; CHD8; ZMAT4; ZNF385B|
|poly(A) RNA binding||RP9; DIMT1L; NIP7; PSMD4; RBM4; SOSTDC1B; RPS4X; RPS18; EIF4G2; EMG1|
|protein binding||PCGF3; TSPAN2; STK40; HRAS; ZNF180; UBE2M; C2orf50; PMP2; HOMER3; RPL22|
|zinc ion binding||CIZ1; PPARG; TET2; CA5B; ADAM22; MSRB1; ADAM18; DIDO1; APOBEC3C; PARK2|
ZMAT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZMAT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZMAT3.
AGO2; PRKRA; STAU1; SIAH1; HNRNPA2B1; DHX9