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Official Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Background This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Synonyms ABCC12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; multidrug resistance-associated protein 9; MRP9; ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12; MGC27071
    • Species :
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse ABCC12-1099M Recombinant Mouse ABCC12 Protein Mammalian Cell His
    Rat ABCC12-403R Recombinant Rat ABCC12 Protein Mammalian Cell His

    abcc12 involved in several pathways and played different roles in them. We selected most pathways abcc12 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with abcc12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCB1A; Abca2; ABCC11; ABCD4; ABCB7; ABCA3; ABCB5; ABCB6; ABCC12; ABCA9

    abcc12 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by abcc12 itself. We selected most functions abcc12 had, and list some proteins which have the same functions with abcc12. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activity KIF3C; KIFC3; MYH8; KIF27; CHD1L; KIF4; KIF25; RNF213; WRN; Abca2
    ATPase activity, coupled to transmembrane movement of substances ABCB1A; SFRP5; ABCC6; ABCD2; ABCG5; ABCA5; Abca2; ABCA3; ABCA1B; ABCG2A
    nucleotide binding ACVR1BA; CDC42L2; PAK2B; ARF3A; POLD1; MAT2AB; ZFML; RND3B; TUBB2; MAPK14A

    abcc12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with abcc12 here. Most of them are supplied by our site. Hope this information will be useful for your research of abcc12.

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