abcc9

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abcc9

Official Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants.
Synonyms ABCC9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; SUR2; ABC37; CANTU; CMD1O; ATFB12
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.Coli or Yeast
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABCC9-3732H Recombinant Human ABCC9, His-tagged E.Coli or Yeast His
    Mouse Abcc9-3734M Recombinant Mouse Abcc9, His-tagged E.Coli or Yeast His
    Rat ABCC9-409R Recombinant Rat ABCC9 Protein Mammalian Cell His
    Zebrafish ABCC9-3267Z Recombinant Zebrafish ABCC9 Mammalian Cell His

    abcc9 involved in several pathways and played different roles in them. We selected most pathways abcc9 participated on our site, such as ABC transporters, ABC-family proteins mediated transport, ATP sensitive Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with abcc9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCG3; ABCC2; ABCB11; ABCB10; ABCA1B; ABCC11; ABCB6; ABCC12; ABCC3; ABCG8
    ABC-family proteins mediated transport KCNJ11; ABCA8; ABCD3B; EIF2S1A; ABCE1; CFTR; ABCC9; ABCG4B; ABCB8; ABCA4A
    ATP sensitive Potassium channels KCNJ8; ABCC9; KCNJ11
    Inwardly rectifying K+ channels KCNJ1B; GNGT2B; KCNJ8; KCNJ2A; KCNJ10; GNGT2A; ABCC9; KCNJ1; KCNJ15; KCNJ1A.5
    Neuronal System KCNA7; KCNF1; KCNJ11; STXBP1A; HCN4; LIN7C; KCNAB2; KCNN3; KCNK18; GRIP1
    Potassium Channels KCNN1B; KCNH1; KCNAB2; ABCC9; KCNK16; KCNN4; KCNA5; KCNK7; KCNAB1A; KCNJ1A.1
    Transmembrane transport of small molecules ANKHA; SLC6A5; SLC6A9; SLC34A2A; ABCA8; ATP1A1A.5; SLCO4A1; CLCNKA; SLC12A7; TFA

    abcc9 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by abcc9 itself. We selected most functions abcc9 had, and list some proteins which have the same functions with abcc9. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CSNK2A2A; MAP2K7; HELB; RIOK1; MAP3K11; GK5; TARS; VPS4B; BMPR1BB; GSG2
    ATPase activity, coupled to transmembrane movement of substances ABCD3; ABCA13; ABCA4; SFRP5; ABCC11; ABCA3; ATP6V1D; ABCD2; ABCB1; ABCB1A
    ion channel binding AP2M1; ACTN3; KCND3; FHL1; DIAP1; SLC8A1; RYR2; RANGRF; KCNQ1; FAM115C
    potassium channel activity KCNH5; KCNK13A; KCNK1A; KCNQ3; KCNK10B; FXYD4; KCNQ4; KCNC1B; KCNIP1; KCNK3A
    potassium channel regulator activity SGK1; KCNV1; SUMO1; CHP; KCNMB1; NEDD4L; DRD4; ADRB2; KCNMB4; SGK2
    sulfonylurea receptor activity ABCC9; ABCC8
    transporter activity AQP3; SLC37A4; SYPB; FXYD2; TCIRG1; TIMM9; OSTB; GABRA5; SLC17A9; PDZK1

    abcc9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with abcc9 here. Most of them are supplied by our site. Hope this information will be useful for your research of abcc9.

    KCNJ11

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