ABCD2 involved in several pathways and played different roles in them. We selected most pathways ABCD2 participated on our site, such as ABC transporters, Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| ABC transporters |
ABCC2; ABCC11; Abcb1b; ABCA1B; ABCD3A; ABCB5; ABCB3L1; ABCC12; ABCC1; ABCB11 |
| Peroxisome |
PEX12; IDH2; ACSL4B; PEX6; ACOX1; PEX10; ACSL5; IDH1; PEX11G; DAO.3 |
ABCD2 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCD2 itself. We selected most functions ABCD2 had, and list some proteins which have the same functions with ABCD2. You can find most of the proteins on our site.
| Function |
Related Protein |
| ATP binding |
MARK3; NPR1; DHX9; HELB; ABCG5; CHEK1; PRKACAA; CHD8; PRKCDA; RPS6KA5 |
| ATPase activity, coupled to transmembrane movement of substances |
ABCB6; ABCB4; TAP1; ABCA4; ABCD3A; ABCC10; ABCG2A; ABCA5; Abcb1b; ABCC8 |
| protein binding |
LDB1; PROL1; HOOK2; CDCP1; CDR2; CYFIP1; POU2F1; MED1; NEURL1B; ORC1L |
| protein homodimerization activity |
GAMT; TFRC; RBM11; IDE; FLT3LG; MLL1; HSP90AA1; HPGDS; AIMP1; RNF17 |
ABCD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCD2.
PEX19; ABCD1
Liu, XX; Liu, JJ; et al. ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 456:129-134(2015).
Park, CY; Kim, HS; et al. ABCD2 Is a Direct Target of beta-Catenin and TCF-4: Implications for X- Linked Adrenoleukodystrophy Therapy. PLOS ONE 8:-(2013).
