ABCD2 Protein


Home / Products / ABCD2


Official Full Name ATP-binding cassette, sub-family D (ALD), member 2
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
Synonyms ABCD2; ATP-binding cassette, sub-family D (ALD), member 2; ALDL1; ATP-binding cassette sub-family D member 2; ALDR; ALDRP; adrenoleukodystrophy-like 1; adrenoleukodystrophy-related protein; ABC39; hALDR;
    • Species :
    • Chicken
    • Dictyostelium discoideum (Slime mold)
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Rattus norvegicus (Rat)
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)-Avi
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse ABCD2-1108M Recombinant Mouse ABCD2 Protein Mammalian Cell His Inquiry
    Mouse Abcd2-8148M Recombinant Mouse Abcd2 protein, His & T7-tagged E.coli His/T7 Inquiry
    Rat ABCD2-410R Recombinant Rat ABCD2 Protein Mammalian Cell His Inquiry
    Chicken ABCD2-4273C Recombinant Chicken ABCD2 Mammalian Cell His Inquiry
    Human ABCD2-9148HCL Recombinant Human ABCD2 293 Cell Lysate HEK293 N/A Inquiry
    Mouse ABCD2-201M Recombinant Mouse ABCD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human ABCD2-3988H Recombinant Human ABCD2 protein, His-tagged E.coli His Inquiry
    Rat ABCD2-65R Recombinant Rat ABCD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Mus musculus (Mouse) RFL15678MF Recombinant Full Length Mouse Atp-Binding Cassette Sub-Family D Member 2(Abcd2) Protein, His-Tagged E.coli expression system His Inquiry
    Dictyostelium discoideum (Slime mold) RFL1925DF Recombinant Full Length Dictyostelium Discoideum Abc Transporter D Family Member 2(Abcd2) Protein, His-Tagged E.coli expression system His Inquiry
    Rattus norvegicus (Rat) RFL2214RF Recombinant Full Length Rat Atp-Binding Cassette Sub-Family D Member 2(Abcd2) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL32048HF Recombinant Full Length Human Atp-Binding Cassette Sub-Family D Member 2(Abcd2) Protein, His-Tagged E.coli expression system His Inquiry

    ABCD2 involved in several pathways and played different roles in them. We selected most pathways ABCD2 participated on our site, such as ABC transporters, Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCC2; ABCC11; Abcb1b; ABCA1B; ABCD3A; ABCB5; ABCB3L1; ABCC12; ABCC1; ABCB11
    Peroxisome PEX12; IDH2; ACSL4B; PEX6; ACOX1; PEX10; ACSL5; IDH1; PEX11G; DAO.3

    ABCD2 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCD2 itself. We selected most functions ABCD2 had, and list some proteins which have the same functions with ABCD2. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activity, coupled to transmembrane movement of substances ABCB6; ABCB4; TAP1; ABCA4; ABCD3A; ABCC10; ABCG2A; ABCA5; Abcb1b; ABCC8
    protein binding LDB1; PROL1; HOOK2; CDCP1; CDR2; CYFIP1; POU2F1; MED1; NEURL1B; ORC1L
    protein homodimerization activity GAMT; TFRC; RBM11; IDE; FLT3LG; MLL1; HSP90AA1; HPGDS; AIMP1; RNF17

    ABCD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCD2.

    PEX19; ABCD1

    Liu, XX; Liu, JJ; et al. ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 456:129-134(2015).
    Park, CY; Kim, HS; et al. ABCD2 Is a Direct Target of beta-Catenin and TCF-4: Implications for X- Linked Adrenoleukodystrophy Therapy. PLOS ONE 8:-(2013).

    Q&As (0)

    Ask a Question for All ABCD2 Products

    Required fields are marked with *

    • Verification Code

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy