ABHD4
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Official Full Name
abhydrolase domain containing 4
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Overview
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. -
Synonyms
ABHD4; abhydrolase domain containing 4; abhydrolase domain-containing protein 4; FLJ12816; alpha/beta-hydrolase 4; lyso-N-acylphosphatidylethanolamine lipase; ABH4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rhesus Macaque
- Zebrafish
- HEK293
- In Vitro Cell Free System
- Insect Cell
- Insect Cells
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ABHD4-078H | Recombinant Human ABHD4 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | ABHD4-3337H | Recombinant Human ABHD4 protein, His-tagged | Insect Cells | His | Met1-Asp342 | |
| Human | ABHD4-675HCL | Recombinant Human ABHD4 cell lysate | Insect Cell | N/A |
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| Human | ABHD4-878HF | Recombinant Full Length Human ABHD4 Protein, GST-tagged | In Vitro Cell Free System | GST | 342 amino acids |
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| Rhesus Macaque | ABHD4-191R | Recombinant Rhesus monkey ABHD4 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | ABHD4-20R-B | Recombinant Rhesus Macaque ABHD4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | ABHD4-20R | Recombinant Rhesus Macaque ABHD4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | ABHD4-2384Z | Recombinant Zebrafish ABHD4 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ABHD4 Related Articles
ABHD4 involved in several pathways and played different roles in them. We selected most pathways ABHD4 participated on our site, such as Glycerophospholipid biosynthesis, Hydrolysis of LPE, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABHD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid biosynthesis | STIL;CHAT;PHOSPHO1;BCHE;PEMT;PLBD1;AGPAT6;CHKA;PLD6 |
| Hydrolysis of LPE | |
| Metabolism | ACOT12;COX16;CPNE6;CYP26A1;AZIN1A;SLC35D2;NUDT11;FAM36A;CYP4F12 |
| Metabolism of lipids and lipoproteins | APOEA;Agmo;LPA;NEU4;FABP1B.1;AGPAT6;APOA4A;AKR1B15;AKR1C21 |
| Phospholipid metabolism | CPNE1;CEPT1A;PEMT;CHKA;CDS1;TPTE;CHKB;CPNE6;AWAT2 |
ABHD4 has several biochemical functions, for example, carboxylic ester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABHD4 itself. We selected most functions ABHD4 had, and list some proteins which have the same functions with ABHD4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carboxylic ester hydrolase activity | FAM135B;ACOT9;Ces2e;CES3A;ACOT2;AADACL4;LYPLAL1;ACOT8;NCEH1 |
ABHD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABHD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABHD4.
TK1; CSNK2B
- Q&As
- Reviews
Q&As (6)
Ask a questionSure, we offer MSDS files and data sheets with detailed product information.
We can offer a bulk quote for each product available on our website. For specific prices, please contact our sales representatives.
The GST tag promotes protein solubility and is used for affinity purification, it may or may not affect protein activity. If you are concerned that the tag may interfere with protein activity, Creative BioMart can also provide custom tag-free ABHD4 protein service.
Sure, and we recommend that you select the conserved motif of the ABHD4 enzyme of the corresponding species.
For example, amino acid residues 50–69 of the mouse ABHD4 protein.
Please provide our scientists with detailed information about the ABHD4 protein you are going to use to prepare the primary antibody, including species, amino acid residue sequence and fusion tag. Experts will offer specific solutions according to experimental requirements.
Customer Reviews (2)
Write a reviewI am glad that I chose ABHD4 recombinant protein from Creative BioMart, it saved me a lot of time.
The scientists at Creative BioMart customized the suitable recombinant protein for me, and it was a very satisfying collaboration.
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