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ABI3

Official Full Name

ABI family, member 3
Overview

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms

ABI3; ABI family, member 3; NESH; SSH3BP3; ABI gene family member 3; new molecule including SH3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ABI3-7165H	Recombinant Human ABI Family, Member 3, His-tagged	E.coli	His	1-366aa	Inquiry
Human	ABI3-088H	Recombinant Human ABI3 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ABI3-089H	Recombinant Human ABI3 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ABI3-3HCL	Recombinant Human ABI3 lysate	HEK293	Non		Inquiry
Human	ABI3-756HF	Recombinant Full Length Human ABI3 Protein, GST-tagged	In Vitro Cell Free System	GST	366 amino acids	Inquiry
Human	ABI3-675H	Recombinant Human ABI3 Protein, MYC/DDK-tagged	HEK293	Myc&DDK		Inquiry
Human	ABI3-483H	Recombinant Human ABI3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	ABI3-1139M	Recombinant Mouse ABI3 Protein	Mammalian Cell	His		Inquiry
Mouse	Abi3-1476M	Recombinant Mouse Abi3 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	ABI3-221M	Recombinant Mouse ABI3 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	ABI3-221M-B	Recombinant Mouse ABI3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ABI3 involved in several pathways and played different roles in them. We selected most pathways ABI3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ABI3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI3 itself. We selected most functions ABI3 had, and list some proteins which have the same functions with ABI3. You can find most of the proteins on our site.

Function	Related Protein
protein binding	MRPL23;FAM120B;CSTF3;SEC61B;ARHGAP17;SH3YL1;SMO;RDBP;MTRR

ABI3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI3.

WAS; NUPL1; CEP44; EIF3H; KRT13; b2r8y4_human

Research Area

Gagete, AP; Franco, L; et al. The Pisum sativum psp54 gene requires ABI3 and a chromatin remodeller to switch from a poised to a transcriptionally active state. NEW PHYTOLOGIST 192:353-363(2011).

del Viso, F; Casaretto, JA; et al. 14-3-3 Proteins are components of the transcription complex of the ATEM1 promoter in Arabidopsis. PLANTA 227:167-175(2007).