Recombinant Full Length Human ABI3 Protein, GST-tagged

• Cat.No.: ABI3-756HF
• Product Overview: Human ABI3 full-length ORF (AAH07780.1, 1 a.a. - 366 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 66.66 kDa
• Protein Length: 366 amino acids
• AA Sequence: MAELQQLQEF EIPTGREALR GNHSALLRVA DYCEDNYVQA TDKRKALEET MAFTTQALAS VAYQVGNLAG HTLRMLDLQG AALRQVEARV STLGQMVNMH MEKVARREIG TLATVQRLPP GQKVIAPENL PPLTPYCRRP LNFGCLDDIG HGIKDLSTQL SRTGTLSRKS IKAPATPASA TLGRPPRIPE PVHLPVVPDG RLSAASSASS LASAGSAEGV GGAPTPKGQA APPAPPLPSS LDPPPPPAAV EVFQRPPTLE ELSPPPPDEE LPLPLDLPPP PPLDGDELGL PPPPPGFGPD EPSWVPASYL EKVVTLYPYT SQKDNELSFS EGTVICVTRR YSDGWCEGVS SEGTGFFPGN YVEPSC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ABI3 ABI family, member 3 [ Homo sapiens ]
• Official Symbol: ABI3
• Synonyms: ABI3; ABI family, member 3; ABI gene family member 3; NESH; SSH3BP3; ABI gene family, member 3; new molecule including SH3
• Gene ID: 51225
• mRNA Refseq: NM_001135186
• Protein Refseq: NP_001128658
• MIM: 606363
• UniProt ID: Q9P2A4