ABTB1
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Official Full Name
ankyrin repeat and BTB (POZ) domain containing 1
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Overview
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. -
Synonyms
ABTB1; ankyrin repeat and BTB (POZ) domain containing 1; ankyrin repeat and BTB/POZ domain-containing protein 1; BPOZ; Btb3; EF1ABP; ABTB 1; Ankyrin repeat and BTB/POZ domain containing 1; Ankyrin repeat and BTB/POZ domain containing protein 1; Elongation factor 1A binding protein; MGC20585; PP 2259; PP2259; elongation factor 1A-binding protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ABTB1 Related Articles
ABTB1 involved in several pathways and played different roles in them. We selected most pathways ABTB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ABTB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ABTB1 has several biochemical functions, for example, protein binding, translation elongation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABTB1 itself. We selected most functions ABTB1 had, and list some proteins which have the same functions with ABTB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HSPA4;RFX1;IRF9;DDX47;TRAF2;CDC45;FBXO28;KL;CSRNP2 |
| translation elongation factor activity | TUFM;EEF1G;EEF1DA;EEF2B;EIF5A;EEF1A2;ABTB1;EEF1A1L2;EEF1B2 |
ABTB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABTB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABTB1.
EEF1A2; CUL3; SMAD9; SMAD2
- Q&As
- Reviews
Q&As (10)
Ask a questionThe ABTB1 protein plays an important role in cell proliferation and apoptosis, and is involved in a variety of cellular signaling pathways.
No disease-associated mutations in the ABTB1 gene have been identified so far.
The expression of the ABTB1 gene is influenced by various factors, including epigenetics, transcription factors, and cellular signaling.
The ABTB1 gene is located on chromosome 13 in the human genome.
The ABTB1 protein is widely expressed in various tissues, including the liver, lungs, heart, kidneys, brain, and intestines.
The ABTB1 protein is composed of multiple ankyrin repeats and a BTB domain, which enable it to function in multiple signaling pathways.
The ABTB1 gene is involved in multiple cellular processes, including the cell cycle, apoptosis, transcriptional regulation, and DNA repair.
ABTB1 is a gene that encodes a protein containing ankyrin repeats and a BTB (Broad-Complex, Tramtrack and Bric a brac) domain.
The ABTB1 protein plays a role in the development of diseases such as cancer, neurological disorders, and autoimmune diseases.
The ABTB1 gene interacts with many other genes, including p53, NF-κB, and STAT3.
Customer Reviews (3)
Write a reviewPerforms exceptionally well in protein crystallization experiments, improving crystal quality and yield.
Provides highly accurate quantification information in mass spectrometry analysis.
Highly sensitive in bioactivity assays, accurately detecting the activity and concentration of bioactive factors.
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