ACBD4

  • Official Full Name

    acyl-CoA binding domain containing 4

  • Overview

    This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    ACBD4; acyl-CoA binding domain containing 4; acyl Coenzyme A binding domain containing 4; acyl-CoA-binding domain-containing protein 4; FLJ13322; ACBD 4; Acyl CoA binding domain containing protein 4; acyl-Coenzyme A binding domain containing 4; HMFT0700;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACBD4-148H Recombinant Human ACBD4 Protein, GST-Tagged Wheat Germ GST
Human ACBD4-9106HCL Recombinant Human ACBD4 293 Cell Lysate HEK293 N/A
Human ACBD4-1064H Recombinant Human ACBD4 Protein (1-305 aa), His-SUMO-tagged E.coli His/SUMO 1-305 aa
Human ACBD4-5039H Recombinant Human ACBD4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ACBD4-763HF Recombinant Full Length Human ACBD4 Protein, GST-tagged In Vitro Cell Free System GST 305 amino acids
Mouse Acbd4-1490M Recombinant Mouse Acbd4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ACBD4-445R Recombinant Rat ACBD4 Protein Mammalian Cell His
Rat ACBD4-100R-B Recombinant Rat ACBD4 Protein Pre-coupled Magnetic Beads HEK293
Rat ACBD4-100R Recombinant Rat ACBD4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ACBD4-12321Z Recombinant Zebrafish ACBD4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

ACBD4 involved in several pathways and played different roles in them. We selected most pathways ACBD4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACBD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ACBD4 has several biochemical functions, for example, fatty-acyl-CoA binding, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACBD4 itself. We selected most functions ACBD4 had, and list some proteins which have the same functions with ACBD4. You can find most of the proteins on our site.

Function Related Protein
fatty-acyl-CoA bindingSCP2;ACBD6;GCDH;PECI;ACOXL;ACOX3;ACOT7;ACADM;ACBD4
lipid bindingEPN1;DBI;RBP2A;CYP21A1;DNM1L;NME4;FABP7;BPIFB3;MARK2

ACBD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACBD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACBD4.

Research Area

Related articles

Ip, BC; Liu, C; et al. Lycopene and Apo-10 '-lycopenoic Acid Have Differential Mechanisms of Protection against Hepatic Steatosis in beta-Carotene-9 ',10 '-oxygenase Knockout Male Mice. JOURNAL OF NUTRITION 145:268-276(2015).
Romao, JM; He, ML; et al. Effect of age on bovine subcutaneous fat proteome: Molecular mechanisms of physiological variations during beef cattle growth. JOURNAL OF ANIMAL SCIENCE 92:3316-3327(2014).
  • Q&As
  • Reviews

Q&As (10)

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What is the role of ACBD4 in the development of metabolic diseases? 09/16/2022

Studies have shown that ACBD4 expression is altered in metabolic diseases such as obesity and diabetes. ACBD4 knockout mice exhibit reduced body weight, improved glucose tolerance, and reduced hepatic steatosis, suggesting that ACBD4 may be a potential target for the treatment of metabolic diseases.

What is the stability of the recombinant human ACBD4 protein under different storage conditions? 09/05/2022

It is generally stable when stored at -20°C or -80°C for up to six months to two years, respectively. However, the protein may be sensitive to freeze-thaw cycles, and repeated freeze-thaw cycles should be avoided. It is also recommended to aliquot the protein upon arrival to minimize the number of freeze-thaw cycles.

Can the recombinant Rat ACBD4 protein be used in functional assays? 03/14/2022

Yes, it can be used in a variety of functional assays, such as enzyme assays, binding assays, and activity assays, to study its biochemical and biophysical properties.

What is the recommended concentration of the Recombinant Human ACBD4 Protein (ACBD4-148H) for use in experiments? 11/11/2021

It may vary depending on the application and the specific experimental conditions. Typically, a concentration of 0.1-1 mg/mL is sufficient for most assays, but this may need to be optimized based on the experimental setup. It is recommended to use a range of concentrations to determine the optimal concentration for a specific experiment.

What is the recommended concentration of recombinant ACBD4 protein for research studies? 09/05/2021

It varies depending on the specific application. It is important to verify the appropriate concentration for each specific application in order to ensure optimal results.

What is the concentration of endotoxin in the recombinant human ACBD4 protein? 12/25/2020

The endotoxin concentration is typically below 1.0 eu/μg of protein, as determined by a Limulus Amebocyte Lysate (LAL) assay. In addition, you can choose the concentration you need when submitting the inquiry form.

Do you sell polyclonal antibodies against human ACBD4? 12/12/2020

You can describe your experimental needs in detail to our scientists, such as WB, IF, IP, IHC, and they will provide professional solutions.

What is the proper way to store the recombinant ACBD4 protein? 08/01/2020

It should be stored at -20°C or -80°C in a non-frost free freezer. It is important to avoid repeated freeze-thaw cycles in order to prevent degradation of the protein. It is recommended that the protein be aliquoted into smaller portions to avoid contamination from repeated use.

What is the structure of ACBD4 protein? 08/03/2019

ACBD4 protein contains an N-terminal acyl-CoA binding domain that binds to long-chain acyl-CoA esters and a C-terminal domain that interacts with the Golgi membrane. It also contains a hydrophobic loop that plays a crucial role in the binding of ACBD4 to the Golgi membrane.

What are the signaling pathways involved in the regulation of ACBD4 expression? 10/07/2017

Several signaling pathways, including the AMP-activated protein kinase (AMPK) and the mammalian target of rapamycin (mTOR) pathways, have been shown to regulate ACBD4 expression.

Customer Reviews (3)

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Reviews
09/16/2022

    I saved a lot of time and effort by purchasing the recombinant human ACBD4 protein from Creative BioMart instead of making it myself.

    02/14/2021

      The recombinant mouse ACBD4 protein from Creative BioMart was reasonably priced and saved me money compared to other suppliers.

      10/07/2020

        I am very satisfied with the quality and performance of the Recombinant Zebrafish ACBD4. It met all of our research needs.

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