Recombinant Human ACBD4 Protein, GST-Tagged
|Product Overview :||Human ACBD4 full-length ORF ( NP_078998.1, 1 a.a. - 305 a.a.) recombinant protein with GST-tag at N-terminal.|
- Gene Information
- Related Products
|Description :||This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]|
|Source :||Wheat Germ|
|Molecular Mass :||61.2 kDa|
|AA Sequence :||MGTEKESPEPDCQKQFQAAVSVIQN LPKNGSYRPSYEEMLRFYSYYKQAT MGPCLVPRPGFWDPIGRYKWDAWNS LGKMSREEAMSAYITEMKLVAQKVI DTVPLGEVAEDMFGYFEPLYQVIPD MPRPPETFLRRVTGWKEQVVNGDVG AVSEPPCLPKEPAPPSPESHSPRDL DSEVFCDSLEQLEPELVWTEQRAAS GGKRDPRNSPVPPTKKEGLRGSPPG PQELDVWLLGTVRALQESMQEVQAR VQSLESMPRPPEQRPQPRPSARPWP LGLPGPALLFFLLWPFVVQWLFRMF RTQKR|
|Applications :||Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
|Notes :||Best use within three months from the date of receipt of this protein.|
|Storage :||Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.|
|Storage Buffer :||50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.|
|Gene Name :||ACBD4 acyl-CoA binding domain containing 4 [ Homo sapiens ]|
|Official Symbol :||ACBD4|
|Synonyms :||ACBD4; acyl-CoA binding domain containing 4; acyl Coenzyme A binding domain containing 4; acyl-CoA-binding domain-containing protein 4; FLJ13322; acyl-Coenzyme A binding domain containing 4; HMFT0700; FLJ90623;|
|Gene ID :||79777|
|mRNA Refseq :||NM_001135704|
|Protein Refseq :||NP_001129176|
|UniProt ID :||Q8NC06|
|◆ Recombinant Protein|
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|ACBD4-1064H||Recombinant Human ACBD4 Protein (1-305 aa), His-SUMO-tagged||+Inquiry|
|ACBD4-12321Z||Recombinant Zebrafish ACBD4||+Inquiry|
|ACBD4-445R||Recombinant Rat ACBD4 Protein||+Inquiry|
|ACBD4-9106HCL||Recombinant Human ACBD4 293 Cell Lysate||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Studies have shown that ACBD4 expression is altered in metabolic diseases such as obesity and diabetes. ACBD4 knockout mice exhibit reduced body weight, improved glucose tolerance, and reduced hepatic steatosis, suggesting that ACBD4 may be a potential target for the treatment of metabolic diseases.
It is generally stable when stored at -20°C or -80°C for up to six months to two years, respectively. However, the protein may be sensitive to freeze-thaw cycles, and repeated freeze-thaw cycles should be avoided. It is also recommended to aliquot the protein upon arrival to minimize the number of freeze-thaw cycles.
Yes, it can be used in a variety of functional assays, such as enzyme assays, binding assays, and activity assays, to study its biochemical and biophysical properties.
It may vary depending on the application and the specific experimental conditions. Typically, a concentration of 0.1-1 mg/mL is sufficient for most assays, but this may need to be optimized based on the experimental setup. It is recommended to use a range of concentrations to determine the optimal concentration for a specific experiment.
It varies depending on the specific application. It is important to verify the appropriate concentration for each specific application in order to ensure optimal results.
The endotoxin concentration is typically below 1.0 eu/μg of protein, as determined by a Limulus Amebocyte Lysate (LAL) assay. In addition, you can choose the concentration you need when submitting the inquiry form.
You can describe your experimental needs in detail to our scientists, such as WB, IF, IP, IHC, and they will provide professional solutions.
It should be stored at -20°C or -80°C in a non-frost free freezer. It is important to avoid repeated freeze-thaw cycles in order to prevent degradation of the protein. It is recommended that the protein be aliquoted into smaller portions to avoid contamination from repeated use.
ACBD4 protein contains an N-terminal acyl-CoA binding domain that binds to long-chain acyl-CoA esters and a C-terminal domain that interacts with the Golgi membrane. It also contains a hydrophobic loop that plays a crucial role in the binding of ACBD4 to the Golgi membrane.
Several signaling pathways, including the AMP-activated protein kinase (AMPK) and the mammalian target of rapamycin (mTOR) pathways, have been shown to regulate ACBD4 expression.
Customer Reviews (3)Write a review
I saved a lot of time and effort by purchasing the recombinant human ACBD4 protein from Creative BioMart instead of making it myself. -
The recombinant mouse ACBD4 protein from Creative BioMart was reasonably priced and saved me money compared to other suppliers. -
I am very satisfied with the quality and performance of the Recombinant Zebrafish ACBD4. It met all of our research needs. -
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