ADAM7
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Official Full Name
ADAM metallopeptidase domain 7
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Overview
This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. -
Synonyms
ADAM7; ADAM metallopeptidase domain 7; a disintegrin and metalloproteinase domain 7; disintegrin and metalloproteinase domain-containing protein 7; EAPI; GP 83; Sperm maturation related glycoprotein GP83; epididymal apical protein I; sperm maturation-related glycoprotein GP-83; GP83; GP-83; ADAM 7; ADAM-7;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ADAM7 Related Articles
ADAM7 involved in several pathways and played different roles in them. We selected most pathways ADAM7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ADAM7 has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM7 itself. We selected most functions ADAM7 had, and list some proteins which have the same functions with ADAM7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | ECEL1;ADAM20;NLN;MBTPS2;ADAM15;UQCRC2B;YBEY;MMP30;YME1L1 |
| zinc ion binding | ZDHHC21;ZCCHC17;RBM14A;IRGF4;MORC3B;TRIM41;ZNF8;RNF114;ZDHHC23B |
ADAM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM7.
- Q&As
- Reviews
Q&As (14)
Ask a questionWe can customize protein production according to your specific needs, you can discuss it with our experts first.
ADAM7 plays positive roles in the migration and invasion of trophoblast cells.
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There are relevant information in our product brochures, and you can also consult relevant questions with our experts.
Our experts can help you choose the right product for your specific needs.
ADAM7 is localized on the sperm surface, ADAM7 is synthesized in the epididymis and is subsequently secreted and transferred to the sperm surface.
We can customize ADAM7 protein according to your specific requirements.
ADAM7 and ADAM28 have a high degree of homology.
Our commonly used purification methods include hydrophobic chromatography, affinity chromatography, ion exchange chromatography, salting out, molecular sieve, etc.
ADAM7 is specifically expressed in the epididymis.
Overexpression of ADAM7 promotes cell proliferation, migration and invasion, and inhibits apoptosis.
Yes, the level of ADAM7 will be reduced.
We do not currently offer ADAM7-related antibodies, but our experts are able to advise you on antibody purchases.
This depends on your specific purchase quantity.
Customer Reviews (5)
Write a reviewThe staff followed up the progress of my experiments in real time, and they would help me solve the problems that appeared in the experiments immediately.
The customer service attitude is patient, careful answers, and detailed answers to my questions.
The product user manual recorded detailed information about ADAM7 protein, which gave me more information about ADAM7.
The parameters of the product I received are consistent with the product information, and the price is relatively favorable.
This is a purchase that satisfies me. In WB, I got a clear ADAM7 band.
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