ADAMTS7
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Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 7
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Overview
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; ADAM-TS7; ADAMTS-7; ADAM-TS 7; A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- N
- Involved Pathway
- Protein Function
- Interacting Protein
ADAMTS7 involved in several pathways and played different roles in them. We selected most pathways ADAMTS7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ADAMTS7 has several biochemical functions, for example, hydrolase activity, metal ion binding, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS7 itself. We selected most functions ADAMTS7 had, and list some proteins which have the same functions with ADAMTS7. You can find most of the proteins on our site.
Function | Related Protein |
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hydrolase activity | GTF2F2A;F2RL1.1;C6AST1;TDRD9;CTSLA;ABHD16A;FAAH2A;PXYLP1;NT5C3L |
metal ion binding | RORAA;CYBB;RUFY4;PRDM1;ZFP146;ZNF83;HEPHL1;ATP1A3;B4GALT5 |
metalloendopeptidase activity | ADAM33;MMP2;C6AST4;MMP16;OSGEPL1;ECE1;ADAMTS12;MMP14B;ADAMTS16 |
metallopeptidase activity | BRCC3;XPNPEP2;CPD;ERAP2;HE2;C6AST1;AFG3L2;CLCA3;ACY1 |
peptidase activity | KLK7;PCSK7;CTSB;PPPDE1;F9A;CTSBA;FAM49BA;MPND;REN2 |
zinc ion binding | PCGF5A;SUV39H2;KAT6A;LDB3A;USP3;ZCRB1;LMCD1;RORA;FTR14 |
ADAMTS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS7.
- Q&As
- Reviews
Q&As (5)
Ask a questionADAMTS7 is also currently used in the study of diseases such as hepatocellular carcinoma and oral cancer.
ADAMTS7 can cleave TSP1.
ADAMTS7 is involved in mediating endothelial proliferation and vascular smooth muscle cell migration after arterial balloon injury. It also promotes degradation of thrombin-sensitive protein-1, inhibits reendothelialization of injured arteries, and promotes vascular remodeling.
ADAMTS7 has the highest homology with ADAMTS12.
ADAMTS7 is strongly associated with atherosclerosis, acute myocardial infarction and ischemia/reperfusion injury.
Customer Reviews (3)
Write a reviewCustomer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.
The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
The after-sales service of the product is guaranteed, which has helped me solve many problems in the experiment.
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