ADH1

  • Official Full Name

    Adh1p
  • Overview

    Alcohol dehydrogenase 1A is an enzyme that in humans is encoded by the ADH1A gene.
  • Synonyms

    ADH1;Adh1p;ADC1;ADH alpha subunit;ADH;ADH1A;Alcohol dehydrogenase 1;Aldehyde reductase;YADH 1;EC 1.1.1.1EC 1.1.1.190Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers;required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
Cat.# Product name Source (Host) Species Tag Protein Length Price
ADH1-156 Active Recombinant Entamoeba histolytica ADH1 protein, His-tagged E.coli Entamoeba Histolytica His 360 amino acids
ADH1-1353M Recombinant Mouse ADH1 Protein Mammalian Cells Mouse His
Adh1-778M Recombinant Mouse Adh1 protein, His & T7-tagged E.coli Mouse His&T7 Glu25~Asp228
ADH1-342M Recombinant Mouse ADH1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ADH1-342M-B Recombinant Mouse ADH1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Adh1-541M Recombinant Mouse Adh1 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    ADH1 involved in several pathways and played different roles in them. We selected most pathways ADH1 participated on our site, such as Glycolysis / Gluconeogenesis,Fatty acid degradation,Tyrosine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemical carcinogenesis ADH7,UGT1A6A,GSTM1,CYP2C8,NAT1,CCBL2,CYP1A1,GSTM2,MGST2,GSTT2
    Metabolism of xenobiotics by cytochrome P UGT1AB,UGT1A1,MGST2,UGT1A6A,CBR1,GSTM5,UGT2A2,MGST3,ALDH3B2,UGT1A6
    Retinol metabolism CYP26C1,CYP4A12A,RDH8,Aldh1a7,RPE65C,RDH8A,UGT5G1,CYP3A41A,DGAT1A,CYP4A10
    Drug metabolism - cytochrome P UGT1A7,UGT1A9,AOX3,UGT1A6,GSTT1,GSTP1,MGST1,FMO1,GSTM,GSTAL
    Metabolic pathways ATP5E,PNP6,ALOX12E,HMGCL,ALDH3B1,ALG13,ALDH4A1,AMPD3B,CYP2C70,POLR2F
    Glycolysis / Gluconeogenesis HK3,MINPP1,PGAM1A,G6PC2,ADH1C,ALDOAA,HK2,FBP2,ENO1A,ALDH2
    Fatty acid degradation ADH6,GCDHA,GCDHB,ALDH9A1B,ACADS,CPT1C,ALDH3A2,ADH5,ALDH7A1,ACADVL
    Tyrosine metabolism MAOB,AOX1,ALDH3A1,AOC2,HPDA,COMTA,DCT,ADH2-2,TYRP1,DBH

    Protein Function

    ADH1 has several biochemical functions, for example, NAD binding,alcohol dehydrogenase (NAD) activity,drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADH1 itself. We selected most functions ADH1 had, and list some proteins which have the same functions with ADH1. You can find most of the proteins on our site.

    Function Related Protein
    ethanol binding ADH7,PRKCE,ADH4
    alcohol dehydrogenase (NAD) activity ADH6,ADH4,DHRS9,ADH5,ADH8A,ADH1C,ADH8B,ADH7,ADH1A
    retinol dehydrogenase activity ADH4,HSD17B6,DHRS7C,RDH1,RDH10,AKR1C3,SDR9C7,BMP2,ADH7,DHRS9
    NAD binding GPD1C,ME3,HSD17B10,AOX1,HADHA,HPGD,CTBP2A,HSD3B5,ME2,CTBP2L
    oxidoreductase activity TM9SF1,RDH13,CYP2AA3,MOXD1L,CYB5RL,CYP2AA7,CYB561A3A,GPD1A,PPM1NA,YWHABL
    drug binding GLRB,CHRNB4,CHRNB3,SLC6A4A,SRP54B,FASN,PPARD,DRD1A,PDXK,P2RX4
    zinc ion binding FTR54,BTR06,ZFAND2B,CA8,RNF126,MMP14B,NEURL1B,SP140,ZDHHC19,ZNRF3
    metal ion binding COX4I2,IRF2BP1,PDLIM5B,ALKBH5,RAF1A,TRMT13,TP63,CYBRD1,NKD2B,COL27A1B
    protein homodimerization activity IRAK3,GPD1C,KIAA1804,KLHL7,PVRL2L,G6PD,HLA-G,CHMP4C,SRM,ABP1

    Interacting Protein

    ADH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADH1.

    Ywhae;Ywhaz;Pgls;Hsd3b7

    Resources

    References

    • Ardizzoni, A; Posteraro, B; et al. AN ANTIBODY REACTIVITY-BASED ASSAY FOR DIAGNOSIS OF INVASIVE CANDIDIASIS USING PROTEIN ARRAY. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY 27:403-412(2014).
    • Chiang, CP; Wu, CW; et al. Expression Pattern, Ethanol-Metabolizing Activities, and Cellular Localization of Alcohol and Aldehyde Dehydrogenases in Human Small Intestine. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 36:2047-2058(2012).

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