ADM2
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Official Full Name
adrenomedullin 2
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Synonyms
ADM2;adrenomedullin 2;28898;ENSG00000128165;AM2;dJ579N16.4;22q13.33;FLJ21135;ADM2;ADM2;intermedin;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- Protein Conjugation
- His
- His (Fc)
- Avi
- N
- Involved Pathway
- Protein Function
- Interacting Protein
ADM2 involved in several pathways and played different roles in them. We selected most pathways ADM2 participated on our site, such as Calcitonin-like ligand receptors, Class B/2 (Secretin family receptors), G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcitonin-like ligand receptors | ADM;ADM2A;ADM2;CALCB;RAMP1;CALCRL;RAMP2;CALCA;RAMP3 |
Class B/2 (Secretin family receptors) | RAMP2;PTH;CRHB;RCA2.1;RAMP1;CALCRL;CRHR2;PTHLH;EMR1 |
G alpha (s) signalling events | ADORA2A;INSL3;ADORA2B;CALCRL;ADCYAP1;CALCA;PTHLHA;ADCYAP1R1;ADCYAP1B |
GPCR downstream signaling | GNA13B;DCLRE1B;CRH;TAS2R13;RGS19;RGS18;CNR2;CXCR7B;TAC1 |
GPCR ligand binding | CCR7;CCBP2;ZFPM2B;GPR17;LPAR2B;FPR-RS3;SSTR4;GPR55;NPB |
Signal Transduction | GPR37B;ZFPM2B;NPS;ANXA1C;SCT;TAC1;GHRB;NRP2B;TAGAP1 |
Signaling by GPCR | PENK;PENKA;NPB;PNOCB;NET1;GPR4;RGS6;PROKR1;ZFPM2B |
ADM2 has several biochemical functions, for example, hormone activity, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADM2 itself. We selected most functions ADM2 had, and list some proteins which have the same functions with ADM2. You can find most of the proteins on our site.
Function | Related Protein |
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hormone activity | SST;CSH2;UCN3L;ADM2A;EDN1;INSB;INSL6;LEP;PTH1B |
protein complex binding | ST13;KRT8;TRAF2;CALCA;EPCAM;ING2;WASF1;NFKBIA;PFKP |
ADM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADM2.
- Q&As
- Reviews
Q&As (9)
Ask a questionADM2 agonists are still in the experimental stage and are not yet available for clinical use. However, several drug candidates are currently being evaluated in preclinical studies and clinical trials, and may eventually be developed as new therapies for the treatment of pain and other disorders.
ADM2 proteins have been implicated in the regulation of pain perception. ADM2 has been shown to decrease pain sensitivity in animal models of chronic pain, and ADM2 agonists may be potential treatments for chronic pain conditions.
There is some evidence to suggest that ADM2 agonists may have therapeutic potential in the treatment of anxiety and depression. However, more research is needed to determine the safety and efficacy of ADM2 agonists for these conditions.
ADM2 proteins are being studied for potential therapies for cardiovascular disease because of their vasodilatory and cardioprotective effects. ADM2 agonists, which mimic the activity of ADM2, are being developed as potential treatments for hypertension, heart failure, and other cardiovascular disorders.
ADM2 proteins can interact with the immune system in several ways. ADM2 has been shown to modulate the activity of immune cells, including T cells, B cells, and macrophages. ADM2 can promote the production of anti-inflammatory cytokines and inhibit the production of pro-inflammatory cytokines.
Unlike opioids, ADM2 agonists do not bind to opioid receptors and therefore do not produce the same side effects associated with opioid use, such as addiction and respiratory depression. ADM2 agonists may offer a safer alternative for the management of chronic pain.
ADM2 agonists could have a significant impact on the opioid epidemic by providing a safer alternative for pain management. Unlike opioids, ADM2 agonists do not produce the same addictive effects, respiratory depression, or risk of overdose. By providing a non-addictive alternative for pain management, ADM2 agonists could help reduce the number of people who become addicted to opioids. Additionally, ADM2 agonists could potentially be used to help people who are already addicted to opioids to manage their pain without increasing their risk of overdose or other adverse effects.
There have been no reported side effects associated with ADM2 agonists in clinical trials to date. However, as with any new drug, long-term safety and efficacy will need to be established in larger clinical studies.
ADM2 proteins have been studied as a potential biomarker for sepsis, a life-threatening condition that occurs when the body's immune response to infection becomes dysregulated. ADM2 levels have been shown to be elevated in patients with sepsis, and may be useful for diagnosing and monitoring the condition.
Customer Reviews (4)
Write a reviewThe manufacturer's attention to detail in the protein's production process is evident, and I am confident that this product will provide me with accurate and dependable data.
the unparalleled technical support provided by the manufacturer has given me the confidence that any challenges I may encounter can be swiftly and effectively resolved.
the purity and consistency of the ADM2 protein have exceeded my expectations, ensuring that my experiments will yield reliable and reproducible results.
After conducting extensive research, I have determined that ADM2 protein is of exceptional quality and will undoubtedly meet all of my experimental requirements.
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