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ADRA1D

  • Official Full Name

    adrenoceptor alpha 1D

  • Synonyms

    ADRA1D;adrenoceptor alpha 1D;280;ENSG00000171873;DAR;ADRA1;ADRA1A;ADRA1R;ALPHA1;dJ779E11.2;20p13;alpha-1D adrenergic receptor;alpha-1D adrenergic receptor;alpha-1D adrenoceptor;alpha-1D adrenoreceptor;alpha-1A adrenergic receptor;alpha-1D-adrenergic receptor;alpha-adrenergic receptor 1a;adrenergic, alpha-1A-, receptor;adrenergic, alpha-1D-, receptor;adrenergic, alpha -1D-, receptor;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADRA1D-3317H Recombinant Human ADRA1D, His-tagged E.Coli or Yeast His 572
Mouse Adra1d-3318M Recombinant Mouse Adra1d, His-tagged E.Coli or Yeast His 562
Rat ADRA1D-540R Recombinant Rat ADRA1D Protein Mammalian Cell His
Rat ADRA1D-196R Recombinant Rat ADRA1D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ADRA1D-196R-B Recombinant Rat ADRA1D Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL-6487HF Recombinant Full Length Human Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged E.coli expression system His Full Length (1-572)
Mus musculus (Mouse) RFL-33084MF Recombinant Full Length Mouse Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged E.coli expression system His Full Length (1-562)
Oryctolagus cuniculus (Rabbit) RFL-11700OF Recombinant Full Length Rabbit Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged E.coli expression system His Full Length (1-576)
Rattus norvegicus (Rat) RFL-14647RF Recombinant Full Length Rat Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged E.coli expression system His Full Length (1-561)
Sus scrofa (Pig) RFL3790SF Recombinant Full Length Pig Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged E.coli expression system His Full Length (1-571)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADRA1D Related Articles
  • ADRA1D Related Research Area

ADRA1D involved in several pathways and played different roles in them. We selected most pathways ADRA1D participated on our site, such as Adrenergic signaling in cardiomyocytes, Adrenoceptors, Amine ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRA1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adrenergic signaling in cardiomyocytesCACNG6A;PLN;MAPK12A;MAPK3;KCNQ1;PPP1CA;CALM3B;SLC8A1;PPP2R5E
AdrenoceptorsADRB1;ADRA2C;ADRB3;ADRA1D;ADRA2B;ADRa1A;ADRB2;ADRA1B;ADRA2A
Amine ligand-binding receptorsCHRM1;DRD3;ADRA2B;ADRA2A;CHRM3;ADRA1D;ADRB2;CHRM2;DRD4
Calcium Regulation in the Cardiac CellCASQ1B;CHRM1;PKIG;CX44.1;GJB2;KCNJ3;ADRB3;RGS14;RGS17
Calcium signaling pathwayLHCGR;CHRM5B;ERBB4A;PHKG1A;CHRM1;LTB4R2;CAMK2G;PLCZ1;NOS3
Class A/1 (Rhodopsin-like receptors)LPAR5A;OXGR1;ACKR4;DRD4;OPN1MW2;PYYA;GPR55A;OPN4.1;CHRM1
G alpha (12/13) signalling eventsARHGEF17;ARHGEF1B;ARHGEF18A;DCLRE1B;MCF2L;ADRA1B;KALRN;ABR;ARHGEF3
G alpha (q) signalling eventsPROK1;GPR68;CHRM5;LPAR2B;RASGRP2;LTB4R;GPR65;ADRA1D;CHRM1

ADRA1D has several biochemical functions, for example, alpha1-adrenergic receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRA1D itself. We selected most functions ADRA1D had, and list some proteins which have the same functions with ADRA1D. You can find most of the proteins on our site.

Function Related Protein
alpha1-adrenergic receptor activityADRA1B;ADRa1A;ADRA1D;ADRA1BB

ADRA1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRA1D here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRA1D.

FLNC

Kordasz, ML; Manicam, C; et al. Role of alpha(1)-Adrenoceptor Subtypes in Pupil Dilation Studied With Gene-Targeted Mice. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:8295-8301(2014).
Ichishima, K; Yamamoto, S; et al. alpha(1)-Adrenoceptor-mediated depletion of phosphatidylinositol 4, 5-bisphosphate inhibits activation of volume-regulated anion channels in mouse ventricular myocytes. BRITISH JOURNAL OF PHARMACOLOGY 161:193-206(2010).
  • Q&As
  • Reviews

Q&As (17)

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How is the ADRA1D receptor related to hypertension? 11/23/2022

The ADRA1D receptor plays a role in regulating the constriction of blood vessels, which affects blood pressure. Dysfunction of the ADRA1D receptor may contribute to the development of hypertension (high blood pressure).

How can knowledge about the ADRA1D protein contribute to advancements in medicine? 08/29/2022

Understanding the function of the ADRA1D protein and its role in different medical conditions can allow researchers to develop more targeted and effective treatments. Additionally, identifying potential genetic mutations in the ADRA1D gene can help with the diagnosis and treatment of certain disorders.

Can drugs that target the ADRA1D protein interact with other medications? 01/19/2022

Yes, drugs that target the ADRA1D protein can interact with other medications, including other blood pressure medications, antidepressants, and medications used to treat erectile dysfunction.

What are the potential side effects of drugs that target the ADRA1D protein? 12/10/2021

Side effects of drugs that target the ADRA1D protein may include dizziness, headaches, fatigue, nausea, and abdominal pain. More serious side effects can include low blood pressure, palpitations, and difficulty breathing.

Can genetic mutations in the ADRA1D gene affect its function? 05/07/2021

Yes, genetic mutations in the ADRA1D gene can affect the function of the ADRA1D protein, potentially leading to altered vasoconstriction, urinary tract function, and neurotransmitter release.

Are there any known mutations in the ADRA1D gene that cause disease? 08/19/2020

There are no known mutations in the ADRA1D gene that cause disease, but certain genetic variations in this gene may be associated with an increased risk of certain conditions, such as hypertension.

In what forms are drugs that target the ADRA1D protein available? 05/30/2020

Drugs that target the ADRA1D protein are typically available in oral tablets or capsules. They can also be administered as injections in a medical setting.

Is there ongoing research on the ADRA1D protein? 11/10/2019

Yes, there is ongoing research on the ADRA1D protein and its potential role in various medical conditions. Researchers are also exploring new drug targets and treatments that target the ADRA1D protein.

What medical conditions are associated with dysfunction of the ADRA1D receptor? 06/29/2019

Dysfunction of the ADRA1D receptor may be associated with various medical conditions, including hypertension, lower urinary tract symptoms, benign prostatic hyperplasia, and depression.

What medical conditions are associated with the ADRA1D protein? 06/16/2019

The ADRA1D protein has been implicated in the development of several medical conditions, including hypertension, urinary incontinence, and neurological disorders such as schizophrenia and bipolar disorder.

Are there any natural substances that target the ADRA1D receptor? 03/21/2019

Yes, certain natural substances have been found to target the ADRA1D receptor, including elderflower extract and apigenin, a flavonoid found in fruits and vegetables.

Can targeting the ADRA1D receptor be a potential therapeutic strategy for certain medical conditions? 01/10/2019

Yes, targeting the ADRA1D receptor can be a potential therapeutic strategy for certain medical conditions, such as hypertension, lower urinary tract symptoms, and depression. However, further research is needed to fully understand its role and potential therapeutic applications.

Are there any drugs that target the ADRA1D receptor? 06/15/2018

Yes, there are drugs that target the ADRA1D receptor, including selective alpha-1 adrenergic receptor antagonists (such as prazosin) and alpha-1 adrenergic agonists (such as phenylephrine).

Is the ADRA1D receptor involved in the development of neurodegenerative diseases? 04/07/2017

There is some evidence that the ADRA1D receptor may be involved in the development of neurodegenerative diseases, such as Alzheimer's disease. However, further research is needed to fully understand its role in these conditions.

Is it safe to use drugs that target the ADRA1D protein during pregnancy or breastfeeding? 06/14/2016

The use of drugs that target the ADRA1D protein during pregnancy or breastfeeding has not been extensively studied and should be used with caution. Pregnant or breastfeeding individuals should consult with their healthcare provider before using these medications.

Are there any drugs that target the ADRA1D protein? 01/26/2016

Yes, several drugs that target the ADRA1D protein have been developed, including prazosin and doxazosin, which are commonly used to treat high blood pressure.

How is the ADRA1D receptor related to lower urinary tract symptoms? 01/18/2016

The ADRA1D receptor is expressed in the smooth muscle cells of the bladder and urethra, and its activation causes relaxation of these muscles. Dysfunction of the ADRA1D receptor may contribute to lower urinary tract symptoms, such as difficulty in urination and urinary incontinence.

Customer Reviews (5)

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Reviews
02/16/2021

    Thanks to the excellent technical support provided by the manufacturer, any queries or concerns I had were promptly resolved, making the entire process seamless and hassle-free.

    07/17/2020

      The ADRA1D protein provided by the manufacturer is of exceptional quality and meets all of my experimental requirements with high specificity and activity.

      06/23/2020

        I also appreciate the detailed protocols and technical information provided by the manufacturer, which have been a valuable resource throughout my project.

        08/21/2019

          the purity and stability of the protein are unparalleled, ensuring reproducible experimental results every time.

          04/07/2018

            I am extremely satisfied with my experience with this product and the manufacturer's outstanding support team, and I highly recommend their products and services.

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