AGFG2
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Official Full Name
ArfGAP with FG repeats 2
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Overview
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3 UTR of this gene contains an insulin receptor substrate 3-like pseudogene. -
Synonyms
AGFG2; ArfGAP with FG repeats 2; HIV 1 Rev binding protein like , HRBL; arf-GAP domain and FG repeats-containing protein 2; RABR; AGFG2_HUMAN; Arf GAP domain and FG repeats containing protein 2; HIV-1 Rev-binding protein-like protein; HIV1 Rev binding protein like protein; HRBL; Nucleoporin; RAB-R; Rev/Rex activation domain-binding protein related; OTTHUMP00000209085; Rev/Rex activation domain binding protein-related;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.Coli or Yeast
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | AGFG2-674H | Recombinant Human AGFG2 | Mammalian Cell | His |
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| Human | AGFG2-530H | Recombinant Human AGFG2 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | AGFG2-3613H | Recombinant Human AGFG2, His-tagged | E.Coli or Yeast | His | 481 |
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| Human | AGFG2-5030H | Recombinant Human AGFG2 Protein, GST-tagged | Wheat Germ | GST |
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| Human | AGFG2-8981HCL | Recombinant Human AGFG2 293 Cell Lysate | HEK293 | N/A |
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| Human | AGFG2-3657HF | Recombinant Full Length Human AGFG2 Protein, GST-tagged | In Vitro Cell Free System | GST | 155 amino acids |
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| Human | AGFG2-2440H | Recombinant Human AGFG2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | AGFG2-2440H-B | Recombinant Human AGFG2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Agfg2-1553M | Recombinant Mouse Agfg2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
AGFG2 involved in several pathways and played different roles in them. We selected most pathways AGFG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AGFG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
AGFG2 has several biochemical functions, for example, GTPase activator activity, metal ion binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by AGFG2 itself. We selected most functions AGFG2 had, and list some proteins which have the same functions with AGFG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | ARHGAP42;FAM13A;ARHGEF12;DEPDC1A;AGFG2;ASAP1A;ARHGAP11A;RASGRP3;TBC1D19 |
| metal ion binding | DGKE;ACACA;RNF216;MB;GLI2A;PPM1LA;LHX1B;ZFP382;CA4B |
| molecular_function | HMCES;IQCJ;ANKRD52A;SAMD1A;REP15;FBXW4;VMN1R137;CDR2;MARVELD2B |
AGFG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGFG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGFG2.
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- Q&As
- Reviews
Q&As (20)
Ask a questionAGFG2 deftly manages the sorting of proteins, ensuring their proper distribution within the cellular realm.
AGFG2's role extends to guiding the movement of cargo within the intricate networks of endosomal trafficking.
AGFG2's tasks could interlink with conditions arising from disruptions in intracellular trafficking.
AGFG2's sphere of influence could potentially intermingle with the pathways regulating autophagy.
AGFG2 is a central player in the art of vesicle budding and the strategic packaging of cargo for its cellular journey.
Absolutely, AGFG2's impact extends to shaping membrane dynamics and orchestrating intracellular trafficking pathways.
Yes, ongoing research continues to peel back the layers of AGFG2's diverse roles and potential impacts.
AGFG2's potential influence extends to orchestrating the harmony of cell signaling pathways through membrane trafficking.
Research endeavors delve into whether AGFG2's roles offer insights into the intricate dance of cancer progression.
AGFG2's multifaceted contributions shape cellular responses to an array of stressors and challenges.
AGFG2 plays a pivotal part in upholding Golgi structure and facilitating the fluidity of vesicle trafficking within Golgi compartments.
AGFG2 boasts a unique protein architecture that's integral to its cellular functions.
Absolutely, AGFG2 is a key contributor to the assembly and movement of clathrin-coated vesicles.
AGFG2 assumes responsibility for vesicle trafficking, regulating the movement of cellular cargo.
AGFG2's active participation in vesicle transport directly impacts and propels cellular secretion processes.
AGFG2, short for "Arf-GAP with FG repeats 2," operates in the realm of intracellular trafficking.
AGFG2's role undergoes scrutiny to determine its potential involvement in the realm of neurodegeneration.
AGFG2 assumes a pivotal role in ensuring the harmonious arrangement of organelles by guiding membrane trafficking.
Research endeavors to dissect AGFG2's roles, interactions, and possible contributions to cellular machinery.
Indeed, AGFG2's mastery of membrane trafficking aids in preserving cellular equilibrium and harmony.
Customer Reviews (5)
Write a reviewThe product consistently demonstrated its efficacy by producing reliable and repeatable outcomes.
The potent effects of the product enhanced our understanding of cellular processes.
The insights gained from the product’s application justified its cost and marked a valuable investment.
Protein AGFG2 consistently activated target genes, yielding reliable results.
The product’s remarkable purity facilitated accurate quantification, minimizing data variability.
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