AGPAT5
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Official Full Name
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
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Overview
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. -
Synonyms
AGPAT5; 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon); 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; FLJ11210; LPAAT e; LPAAT epsilon; 1 acyl sn glycerol 3 phosphate acyltransferase epsilon; 1 acylglycerol 3 phosphate O acyltransferase 5; 1 AGP acyltransferase 5; 1 AGPAT 5; 1 AGPAT5; 1-acylglycerol-3-phosphate O-acyltransferase 5; 1-AGP acyltransferase 5; 1-AGPAT 5; 1AGPAT5; LPAAT-epsilon; Lysophosphatidic acid acyltransferase epsilon; PLCE_HUMAN; LPAATE;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rhesus Macaque
- Zebrafish
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- AGPAT5 Related Articles
AGPAT5 involved in several pathways and played different roles in them. We selected most pathways AGPAT5 participated on our site, such as Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGPAT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | GLYCTK;AKR1B1L;MGLL;ALDH9A1B;ALDH2;AGPAT4;MOGAT3;AKR1A1B;GK2 |
| Glycerophospholipid metabolism | PLA2G4C;CDIPT;PNPLA7;PLA2G4A;LPGAT1;PLA2G16;PLD2;AGXT2L1;GPAT2 |
| Metabolic pathways | GALNT18;HPD;SQLEA;ALAS1;BDH2;NDUFA4;PGAM1B;EXT1B;DPYD |
| Phospholipase D signaling pathway | AVPR1B;AGTR1B;PLCB2;SHC1;ARF6;LPAR4;MS4A2;AGPAT3;KRAS |
AGPAT5 has several biochemical functions, for example, 1-acylglycerol-3-phosphate O-acyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AGPAT5 itself. We selected most functions AGPAT5 had, and list some proteins which have the same functions with AGPAT5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase activity | AGPAT4;AGPAT1;LYCAT;AGPAT3;LCLAT1;LPCAT2;AGPAT9L;AGPAT2;AGPAT9 |
| protein binding | CBX1;VDAC1;FEM1B;HNRNPH1;NCAPH;TFF1;FAM156A;PRAP1;PMM1 |
AGPAT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGPAT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGPAT5.
UBQLN1; 15-deoxy-delta(12,14; E2F3
- Q&As
- Reviews
Q&As (20)
Ask a questionResearch explores how AGPAT5’s function influences overall cellular health and function.
Yes, AGPAT5’s function can influence the remodeling of cellular membranes.
Yes, AGPAT5’s involvement can influence lipid-mediated signaling processes within cells.
Yes, mutations in AGPAT5 can result in metabolic disorders affecting lipid metabolism.
Yes, AGPAT5’s activity affects the composition and properties of cellular membranes.
AGPAT5 adds fatty acids to glycerol-3-phosphate, forming lysophosphatidic acid (LPA).
Research investigates AGPAT5’s role in lipid metabolism through cellular and biochemical assays.
AGPAT5’s function influences the composition and fluidity of cellular lipid bilayers.
Yes, AGPAT5’s activity contributes to the generation of diverse phospholipids for cellular functions.
Yes, AGPAT5’s function can be regulated by cellular stress and metabolic changes.
AGPAT5 plays a key role in lipid metabolism by catalyzing the synthesis of phospholipids.
AGPAT5’s involvement contributes to maintaining lipid balance and cellular health.
AGPAT5’s role can impact the production of lipid-derived second messenger molecules.
AGPAT5’s role in lipid metabolism can impact lipid-mediated signaling processes within cells.
Yes, AGPAT5’s function can be influenced by cellular stress and changes in metabolic state.
AGPAT5 is primarily located in the endoplasmic reticulum (ER) membrane.
AGPAT5’s role influences the dynamics and formation of lipid droplets in cells.
Yes, AGPAT5’s activity can influence cellular growth and proliferation through lipid metabolism.
Yes, AGPAT5’s role can vary based on the specific cellular context and function.
AGPAT5’s activity contributes to maintaining the structural integrity of cellular membranes.
Customer Reviews (5)
Write a reviewThe product’s quality was evident in the absence of background interference in our assays.
The product’s high purity enabled accurate quantification, minimizing data variability.
Replicating results confirmed the product’s reliability and significance in our research.
Reliable protein-protein interactions were achieved due to the product’s pure composition.
The product’s innovative traits allowed us to explore previously unknown cellular processes.
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