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AGPAT6

  • Official Full Name

    1-acylglycerol-3-phosphate O-acyltransferase 6

  • Overview

    Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
  • Synonyms

    AGPAT6; 1-acylglycerol-3-phosphate O-acyltransferase 6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta; glycerol-3-phosphate acyltransferase 6; 1-AGP acyltransferase 6; lysophosphatidic acid acyltransferase zeta; testis spermatogenesis apoptosis-related protein 7; 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta; 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AGPAT6-9478H Recombinant Human AGPAT6, GST-tagged E.coli GST 206-456a.a.
Human AGPAT6-435H Recombinant Human AGPAT6 Protein, GST-tagged Wheat Germ GST
Human AGPAT6-37HCL Recombinant Human AGPAT6 cell lysate N/A
Human AGPAT6-934HF Recombinant Full Length Human AGPAT6 Protein, GST-tagged In Vitro Cell Free System GST 456 amino acids
Mouse AGPAT6-1421M Recombinant Mouse AGPAT6 Protein Mammalian Cell His
Mouse AGPAT6-391M Recombinant Mouse AGPAT6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse AGPAT6-391M-B Recombinant Mouse AGPAT6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish AGPAT6-3735Z Recombinant Zebrafish AGPAT6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AGPAT6 Related Articles

AGPAT6 involved in several pathways and played different roles in them. We selected most pathways AGPAT6 participated on our site, such as CDP-diacylglycerol biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, Glycerolipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGPAT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
CDP-diacylglycerol biosynthesisCDS1;GPAT2;AGPAT2;GK5;AGPAT6;AGPAT1
Fatty acid, triacylglycerol, and ketone body metabolismMED7;ACOT6;MED9;ABCA1;MED20;MED25;MED10;ECI1;APOA5
Glycerolipid metabolismAGPAT1;AGK;PPAP2B;AKR1B8;AGPAT3;DAK;MOGAT1;AKR1B10;AGPAT5
Glycerophospholipid biosynthesisCHAT;CEPT1A;PHOSPHO1;PTPMT1;PLB1;PNPLA8;AGPAT6;AWAT2;PEMT
Glycerophospholipid metabolismLPIN3;DGKG;LYCAT;CHKB;TESCA;ETNK1;CDIPT;LPCAT1;PCYT1BA
Metabolic pathwaysPDHA2;GALT;ATP5C1;OGDHL;LALBA;HIBCH;UGT1A1;OTC;GALNT10
MetabolismSLC25A16;SLC25A15B;MAPK1IP1L;LYVE1;UROC1;CYP2A7;CYP2N13;BSG;SUMF2
Metabolism of lipids and lipoproteinsALOX5B.3;MED19;GLTPD1;PPM1LA;PPM1L;APOEB;ARSJ;PLD6;STARD5

AGPAT6 has several biochemical functions, for example, NOT 1-acylglycerol-3-phosphate O-acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGPAT6 itself. We selected most functions AGPAT6 had, and list some proteins which have the same functions with AGPAT6. You can find most of the proteins on our site.

Function Related Protein
NOT 1-acylglycerol-3-phosphate O-acyltransferase activity
glycerol-3-phosphate O-acyltransferase activityGPAT2;AGPAT6;AGPAT9L;AGPAT9;GPAM

AGPAT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGPAT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGPAT6.

HSD17B7; 1C

Bunel, A; Jorssen, EP; et al. Individual bovine in vitro embryo production and cumulus cell transcriptomic analysis to distinguish cumulus-oocyte complexes with high or low developmental potential. THERIOGENOLOGY 83:228-237(2015).
Sankella, S; Garg, A; et al. Hepatic Gluconeogenesis Is Enhanced by Phosphatidic Acid Which Remains Uninhibited by Insulin in Lipodystrophic Agpat2 Mice*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:4762-4777(2014).
  • Q&As
  • Reviews

Q&As (24)

Ask a question
Can AGPAT6’s involvement affect lipid storage mechanisms 11/09/2022

How does AGPAT6 contribute to cellular membrane structure 06/25/2022

How is AGPAT6’s specific role studied within lipid metabolism 06/10/2022

In which cellular compartments can AGPAT6 be found 06/09/2022

How is AGPAT6’s participation linked to lipid homeostasis 11/27/2021

How does AGPAT6’s function relate to the properties of lipid bilayers 08/14/2021

Is AGPAT6 involved in the diversification of phospholipids 06/18/2021

Does AGPAT6 respond to stress by altering its function 02/07/2021

How is AGPAT6’s impact on overall cellular health studied 11/18/2020

Does AGPAT6 influence lipid droplet dynamics within cells 07/26/2020

Can AGPAT6’s role intersect with intracellular signaling 05/30/2020

How does AGPAT6 impact lipid-mediated signaling pathways 04/08/2020

How is AGPAT6’s role related to the production of lipid second messengers 12/22/2019

What is the specific function of AGPAT6 in lipid metabolism 10/31/2019

How is AGPAT6’s role explored within disease contexts 08/28/2019

Does AGPAT6’s malfunction lead to lipid-related disorders 07/12/2019

In what manner does AGPAT6 influence membrane dynamics 04/14/2019

Can AGPAT6 influence cellular responses to stress 02/01/2019

Does AGPAT6’s role vary based on cell type and function 12/25/2018

Can AGPAT6 be targeted for therapeutic interventions 06/15/2018

Does AGPAT6 contribute to maintaining organelle integrity 05/08/2018

Can AGPAT6’s enzymatic action alter lipid composition 06/27/2017

Can AGPAT6’s enzymatic activity be regulated by signals 01/09/2017

How does AGPAT6’s role relate to maintaining lipid bilayer stability 01/19/2016

Customer Reviews (5)

Write a review
Reviews
04/11/2022

     The product’s ability to modulate signal pathways played a crucial role in our discoveries.

    09/03/2019

       Replicating outcomes across different cell types showcased the product’s consistent behavior.

      01/02/2019

         Compatibility with a range of assays expanded our experimental possibilities significantly.

        09/02/2018

          The consistent outcomes obtained with the product validated its role in our experimental models.

          08/17/2018

            It's innovative features allowed us to explore previously uncharted cellular mechanisms.

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