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Official Full Name 1-acylglycerol-3-phosphate O-acyltransferase 6
Background Lysophosphatidic acid acyltransferases (EC catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
Synonyms AGPAT6; 1-acylglycerol-3-phosphate O-acyltransferase 6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta; glycerol-3-phosphate acyltransferase 6; 1-AGP acyltransferase 6; lysophosphatidic acid acyltransferase zeta; testis spermatogenesis apoptosis-related protein 7; 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta; 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta);
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AGPAT6-37HCL Recombinant Human AGPAT6 cell lysate N/A
    Human AGPAT6-435H Recombinant Human AGPAT6 Protein, GST-tagged Wheat Germ GST
    Human AGPAT6-9478H Recombinant Human AGPAT6, GST-tagged E.coli GST
    Mouse AGPAT6-1421M Recombinant Mouse AGPAT6 Protein Mammalian Cell His
    Zebrafish AGPAT6-3735Z Recombinant Zebrafish AGPAT6 Mammalian Cell His

    AGPAT6 involved in several pathways and played different roles in them. We selected most pathways AGPAT6 participated on our site, such as CDP-diacylglycerol biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, Glycerolipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGPAT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    CDP-diacylglycerol biosynthesis AGPAT6; AGPAT2; AGPAT1; GPAT2; GK5; CDS1
    Fatty acid, triacylglycerol, and ketone body metabolism MED23; ACSF2; SREBF2; MED21; MED15; DGAT1B; GLIPR1; ANKRD1; MED10; G0S2
    Glycerolipid metabolism GLA; GK; GPAM; AGPAT3; ALDH3A2A; PPAP2D; AKR1A1; ALDH9A1A.1; PNPLA2; glpK
    Glycerophospholipid biosynthesis CPNE6; AWAT1; PNPLA8; BCHE; ABHD3; PTPMT1; CPNE7; CHAT; PEMT; CEPT1
    Glycerophospholipid metabolism PCYT1AB; AGPAT2; PPAP2D; MBOAT1; CDS1; TESCA; PLA2G4F; CEPT1; LPCAT2; STIL
    Metabolic pathways RRM2; PIP5K1A; KHK; ALPPL2; POLR1B; UGT2A2; HK3; ISYNA1; PCYT1BA; B4GALT7
    Metabolism STAB2; CYP4T8; PPM1LB; APOF; MED7; ACOT11B; PYGMB; B3GNT3; ACER1; MED20
    Metabolism of lipids and lipoproteins MED15; CYP11B1; CERS3B; AKR1C6; ELOVL1A; FAAH2A; PPARGC1B; PITPNB; CYP2AD6; NFYBA

    AGPAT6 has several biochemical functions, for example, NOT 1-acylglycerol-3-phosphate O-acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGPAT6 itself. We selected most functions AGPAT6 had, and list some proteins which have the same functions with AGPAT6. You can find most of the proteins on our site.

    Function Related Protein
    NOT 1-acylglycerol-3-phosphate O-acyltransferase activity AGPAT6
    glycerol-3-phosphate O-acyltransferase activity AGPAT6; GPAM; GPAT2; AGPAT9; AGPAT9L

    AGPAT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGPAT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGPAT6.

    HSD17B7; 1C

    Bunel, A; Jorssen, EP; et al. Individual bovine in vitro embryo production and cumulus cell transcriptomic analysis to distinguish cumulus-oocyte complexes with high or low developmental potential. THERIOGENOLOGY 83:228-237(2015).
    Sankella, S; Garg, A; et al. Hepatic Gluconeogenesis Is Enhanced by Phosphatidic Acid Which Remains Uninhibited by Insulin in Lipodystrophic Agpat2 Mice*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:4762-4777(2014).

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