AKR1B1 involved in several pathways and played different roles in them. We selected most pathways AKR1B1 participated on our site, such as Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKR1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Pentose and glucuronate interconversions |
DHDH; UGT2A1; UGP2B; ALDH3A2; OXSR1; AKR1B10; RPE; UGT1A7; AKR1A1A; UGDH |
| Fructose and mannose metabolism |
ALDOA; AKR1B10; ALDOB; PFKFB4L; GMPPAA; TSTA3; PFKM; PFKFB4; TPI1B; GMPPA |
| Galactose metabolism |
LALBA; PFKL; G6PC2; AKR1B7; LCT; HK2; GALE; HKDC1; PFKP; AKR1B10 |
| Glycerolipid metabolism |
DGKA; DGAT2; LIPC; LYCAT; AGPAT9; DGKG; PNLIPRP3; DGKB; MGLL; LPIN3 |
| Metabolic pathways |
NDUFB7; ALG10; POLR2F; ATP6V1B1; PKMB; DHRS4L2; DAD1; CYP2P9; PIGQ; NT5E |
AKR1B1 has several biochemical functions, for example, alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, electron carrier activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AKR1B1 itself. We selected most functions AKR1B1 had, and list some proteins which have the same functions with AKR1B1. You can find most of the proteins on our site.
| Function |
Related Protein |
| alditol:NADP+ 1-oxidoreductase activity |
AKR1B1; AKR1B8; AKR1B7; AKR1C3; ADH4; AKR7A2; PRKRA; AKR7A5; Akr1b3; AKR1C21 |
| aldo-keto reductase (NADP) activity |
AKR7A3; AKR1B10; SDR42E1; KCNAB1; AKR1B1; AKR1C4; H2-KE6; HSD3B5; SDR16C6; KCNAB2 |
| electron carrier activity |
ACAD8; NDUFV2; DHDH; MAOB; ETFA; TXNRD3; AOX3; AOX3L1; HSD17B6; ALDH2 |
| glyceraldehyde oxidoreductase activity |
AKR1B1; Akr1b3 |
AKR1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKR1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKR1B1.
PRMT2; 13529257; ZNF253; DSP; TFE3; MCC; PAX7; HLA-B; VHL; DST; IKBKE; CSMD1; TRAF6; SMAD1
