|Official Full Name||aldehyde dehydrogenase 5 family, member A1|
|Background||This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.|
|Synonyms||ALDH5A1; aldehyde dehydrogenase 5 family, member A1; succinate-semialdehyde dehydrogenase, mitochondrial; SSADH; SSDH; succinate semialdehyde dehydrogenase; aldehyde dehydrogenase family 5 member A1; mitochondrial succinate semialdehyde dehydrogenase; NAD|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
aldh5a1 involved in several pathways and played different roles in them. We selected most pathways aldh5a1 participated on our site, such as Alanine, aspartate and glutamate metabolism, Butanoate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh5a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Alanine, aspartate and glutamate metabolism||GPT2; GOT2A; GLUD2; AGXT2; GLSA; GLS2; NAT8L; ABAT; ASPA; DDO|
|Butanoate metabolism||HMGCL; ACSM3; DHRS13L1; OXCT1B; GAD1B; ABAT; L2HGDH; HADHA; AACS; BDH1|
|Metabolic pathways||GALNT11; BTD; UCK2A; NDST4; H6PD; CBSB; ABP1; GLSA; GCH2; PON2|
aldh5a1 has several biochemical functions, for example, aldehyde dehydrogenase (NAD) activity, protein homodimerization activity, succinate-semialdehyde dehydrogenase (NAD+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh5a1 itself. We selected most functions aldh5a1 had, and list some proteins which have the same functions with aldh5a1. You can find most of the proteins on our site.
|aldehyde dehydrogenase (NAD) activity||ALDH8A1; ALDH2; ALDH6A1; ALDH1B1; ALDH9A1; ALDH3A1; ALDH3A2A; ALDH3A2B; ALDH5A1; ALDH9A1A.1|
|protein homodimerization activity||MBL1; SLC9A7; CLIC6; PVRL3B; NR6A1; BOKA; UNC13A; CITED1; PVRL1A; PDGFC|
|succinate-semialdehyde dehydrogenase (NAD+) activity||ALDH5A1|
|succinate-semialdehyde dehydrogenase [NAD(P)+] activity||ALDH5A1|
aldh5a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh5a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh5a1.