ALP
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Overview
Alkaline phosphatase (ALP, ALKP) (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. -
Synonyms
Alkaline phosphatase liver/bone/kidney isozyme protein; alkaline phosphatase; liver/bone/kidney protein; tissue-nonspecific isozyme protein; alkaline phosphomonoesterase protein; AP-TNAP protein; APTNAP protein; EC 3.1.3.1 protein; F;
- Native Proteins
- Assay Kits
- Calf
- Pig
- Calf
- Porcine Kidney
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Calf | ALP-8330C | Native Calf ALP | Calf | N/A |
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| Pig | ALP-151P | Active Native Porcine Kidney Alkaline Phosphatase | Porcine Kidney | N/A |
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| Kit-2285 | Alkaline Phosphatase Activity Colorimetric Assay Kit | N/A |
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| Kit-0080 | Alkaline Phosphatase Fluorometric Assay Kit | N/A |
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| Kit-0081 | Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence) | N/A |
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| Kit-0078 | Alkaline Phosphatase Colorimetric Assay Kit | N/A |
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| Kit-0865 | Alkaline Phosphatase Fluorometric Assay Kit (Near Infrared) | N/A |
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| Kit-0079 | Alkaline Phosphatase Assay Kit | N/A |
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- ALP Related Articles
ALP involved in several pathways and played different roles in them. We selected most pathways ALP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ALP has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ALP itself. We selected most functions ALP had, and list some proteins which have the same functions with ALP. You can find most of the proteins on our site.
| Function | Related Protein |
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ALP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALP here. Most of them are supplied by our site. Hope this information will be useful for your research of ALP.
- Q&As
- Reviews
Q&As (13)
Ask a questionA comprehensive examination, such as liver function and bone densitometry, is usually required to determine the specific cause.
ALP mainly exists in the skeletal system, so bone diseases can lead to increased ALP, such as osteoporosis and bone metastatic cancer.
Elevated ALP is only one indicator, and its significance varies in different circumstances, but it does not necessarily mean that there is a serious disease that requires further diagnosis.
Obstruction of the biliary tract leads to cholestasis, which in turn leads to an increased ability of the liver to synthesize ALP, so ALP is elevated.
Disease-specific treatments are needed to effectively reduce ALP levels.
There is no significant association between elevated ALP and AIDS.
Elevated ALP itself does not require treatment, but if there is an underlying disease, it does.
ALP testing is usually done by drawing blood.
When ALP is elevated, patients usually experience fatigue, loss of appetite, abdominal pain, jaundice and other symptoms.
The liver is mainly responsible for the synthesis and release of ALP, so liver diseases can lead to elevated ALP, such as hepatitis and cirrhosis.
Elevated ALP by itself does not lead to complications, but if there is an underlying condition, untreated may lead to related complications.
When the above related symptoms occur, an ALP test is required.
When ALP is elevated, it is important to avoid eating high-fat foods and drinking alcohol.
Customer Reviews (4)
Write a reviewStability of ALP means that we can easily store it and use it at any time without worrying about its performance degradation.
The purity is high, showing good control of the production process.
This repeatability is good, which can reduce the error in the experiment and improve the repeatability of the experiment.
ALP showed excellent performance in Western blot and did not affect its performance even when stored for a long time.
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