amph
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  • Official Full Name
  • amphiphysin
  • Background
  • This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.
  • Synonyms
  • AMPH; amphiphysin; amphiphysin (Stiff Man syndrome with breast cancer 128kDa autoantigen) , amphiphysin (Stiff Mann syndrome with breast cancer 128kD autoantigen); amphiphysin I; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); AMP
Cat.#:AMPH-402HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AMPH Protein, His-tagged
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Cat.#:Amph-403MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Amph Protein, His-tagged
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Cat.#:Amph-404RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Amph Protein, His-tagged
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Cat.#:AMPH-312HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AMPH protein, GST-tagged
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Cat.#:AMPH-1609MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AMPH Protein
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Cat.#:Amph-3432RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Amph, His-tagged
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Cat.#:AMPH-660RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AMPH Protein
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Cat.#:AMPH-1216CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AMPH
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Cat.#:AMPH-3431CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AMPH, His-tagged
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Cat.#:AMPH-11085ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AMPH
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Cat.#:AMPH-8875HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human AMPH 293 Cell Lysate
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Involved Pathway

AMPH involved in several pathways and played different roles in them. We selected most pathways AMPH participated on our site, such as Endocytosis, Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
SPG21; AGAP2; ZFYVE9; VPS24; SH3GLB2; ARF6B; PARD6GB; CHMP6B; RET; RHOAA
Fc gamma R-mediated phagocytosis
PLA2G4F; MAPK3; SPHK1; cgr2b; ASAP3; PLCG2; WAS; PPAP2A; FCGR1A; PLA2G4D

Protein Function

AMPH has several biochemical functions, for example, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMPH itself. We selected most functions AMPH had, and list some proteins which have the same functions with AMPH. You can find most of the proteins on our site.
Function
Related Protein
Function phospholipid binding
Related Protein PON1; PLEKHA3; ANXA9; PLA2G15; TEC; ANXA5; NOXO1; TICAM2; NBEAL2; CPS1
Function protein binding
Related Protein TMEM120B; DEDD; SV2B; TXNL4B; GBF1; TP53BP1; GFI1B; RCAN1; ETV7; RBMX

Interacting Protein

AMPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMPH here. Most of them are supplied by our site. Hope this information will be useful for your research of AMPH.
DNM1; DNM2; Ap2a2; Necap1; SYNJ1

AMPH Related Articles

Calipari, ES; Sun, HG; et al. Amphetamine Self-Administration Attenuates Dopamine D2 Autoreceptor Function. NEUROPSYCHOPHARMACOLOGY 39:1833-1842(2014).
Matthies, HJG; Moore, JL; et al. Rab11 Supports Amphetamine-Stimulated Norepinephrine Transporter Trafficking. JOURNAL OF NEUROSCIENCE 30:7863-7877(2010).