AMY1B
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Official Full Name
amylase, alpha 1B (salivary)
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Overview
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. -
Synonyms
AMY1B; amylase, alpha 1B (salivary); AMY1, amylase, alpha 1B; salivary; alpha-amylase 1; 1,4-alpha-D-glucan glucanohydrolase; 1,4-alpha-D-glucan glucanohydrolase 1; AMY1; Amylase, alpha 1B; Amylase, salivary, alpha-1B; EC 3.2.1.1; Glycogenase; MGC177995; OTTHUMP00000012691; Salivary alpha-amylase; Salivary amylase alpha 1B; AMY1A; AMY1C;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | AMY1B-534H | Recombinant Human AMY1B protein, GST-tagged | Wheat Germ | GST |
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| Human | AMY1B-8874HCL | Recombinant Human AMY1B 293 Cell Lysate | HEK293 | N/A |
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| Human | AMY1B-31376TH | Native Human AMY1B | N/A |
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| Human | AMY1B-1030HF | Recombinant Full Length Human AMY1B Protein, GST-tagged | In Vitro Cell Free System | GST | 511 amino acids |
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- Involved Pathway
- Protein Function
- Interacting Protein
AMY1B involved in several pathways and played different roles in them. We selected most pathways AMY1B participated on our site, such as Starch and sucrose metabolism, Metabolic pathways, Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMY1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Starch and sucrose metabolism | AGL;UGT1A2;AMY2A4;Amy1;UGT5G1;GPIA;GANC;UGT2A2;HKDC1 |
| Metabolic pathways | UGT1A3;GBA3;DHRS9;CYP3A41B;PNAT10;ATP6V0E;ALDH9A1B;MTMR4;MINPP1A |
| Salivary secretion | ATP1B4;CALM2;PRH2;CAMP;CALM1;ATP1B2;ATP1B1;ATP1A4;KCNN4 |
| Carbohydrate digestion and absorption | SI;PIK3R5;AMY2A2;ATP1B3;HK1;AKT1;AMY1B;AMY1A;G6PC |
AMY1B has several biochemical functions, for example, alpha-amylase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMY1B itself. We selected most functions AMY1B had, and list some proteins which have the same functions with AMY1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-amylase activity | AMY2A2;AMY1B;AMY2A3;Amy1;AMY2A;AMY2A4;AMY2A5;AMY2B;AMY1A |
| metal ion binding | BHLHE22;ADAR;RASAL1;FIBCD1;RXRAB;NAIP6;Adamts19;NR2F6A;KDM6BB |
| protein binding | MOS;AXIN2;PAGE2;WIPF1;PER2;ARHGEF7;GPRC5A;TAOK1;ALAS2 |
AMY1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMY1B here. Most of them are supplied by our site. Hope this information will be useful for your research of AMY1B.
MUC7; CDK2AP1; SOD2; RASSF6
- Q&As
- Reviews
Q&As (9)
Ask a questionThe role of AMY1B gene variations in obesity or weight regulation has not been extensively studied. Most of the existing research on this topic has focused on the AMY1A gene and its association with obesity risk. Therefore, it is unclear if and how AMY1B gene variations may be related to obesity. Further research is needed to explore this potential association.
Similar to AMY1A, the expression and activity of the AMY1B gene may be influenced by various factors. This can include dietary factors such as carbohydrate intake, genetic factors, and environmental factors. More research is needed to fully understand the regulation and potential influences on AMY1B gene expression and activity.
As mentioned earlier, the AMY1B gene has been less studied compared to AMY1A. While variations or mutations in the AMY1A gene are known to influence starch digestion efficiency, there is limited information on the specific impact of AMY1B gene variations on this process. Further research is needed to determine if and how AMY1B gene variations might affect starch digestion efficiency.
Currently, there are no known diseases or disorders specifically associated with the AMY1B protein. However, it is important to note that research on this protein is relatively limited compared to AMY1A, so there may be more to discover in the future.
The AMY1B protein and the AMY1A protein are two isoforms of the α-amylase protein. They are encoded by different genes, AMY1B and AMY1A, respectively. While both proteins are involved in carbohydrate digestion, they may have slight differences in their enzymatic activity or expression patterns. However, further research is needed to fully understand the functional distinctions between these two isoforms.
The AMY1B gene, like other genes, is heritable. It is passed down from parents to offspring in a Mendelian manner. However, the extent of gene copy number variation for AMY1B and its heritability patterns are not as well-studied as AMY1A. It is important to consider genetic and environmental factors that may influence AMY1B gene expression and activity.
The expression pattern of the AMY1B gene in different tissues has not been extensively studied. However, it is generally believed that the AMY1B gene is primarily expressed in salivary glands, similar to the AMY1A gene. This is because both genes code for enzymes involved in starch digestion, and salivary glands are one of the major sites where α-amylase is produced.
The AMY1B gene is relatively less studied compared to AMY1A, and as a result, less is known about genetic mutations or variations specifically related to AMY1B. Further research is needed to fully understand the genetic variability and potential impact of AMY1B gene variations.
Currently, there are no known genetic disorders specifically associated with the AMY1B gene. However, it is important to note that research on this gene is relatively limited, and new discoveries may be made in the future that shed light on potential disorders or conditions related to AMY1B.
Customer Reviews (5)
Write a reviewAMY1B protein is an enzyme involved in the digestion of carbohydrates, specifically starch.
A reliable manufacturer ensures the production and purification of AMY1B protein, maintaining its quality and purity.
Such support helps researchers overcome challenges and obtain reliable results.
Manufacturers might offer customization options, such as different variants or modifications of the AMY1B protein, to cater to specific research requirements.
Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.
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