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Official Full Name anaphase promoting complex subunit 11
Background Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Synonyms ANAPC11; anaphase promoting complex subunit 11; APC11; Apc11p; MGC882; HSPC214; Anaphase-promoting complex subunit 11; Cyclosome subunit 11; Hepatocellular carcinoma-associated RING finger protein; APC11 anaphase promoting complex subunit 11 homolog; anaphase promoting complex subunit 11 (yeast APC11 homolog)
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANAPC11-010H Recombinant Human ANAPC11 Protein, His-tagged E.coli His
    Human ANAPC11-542H Recombinant Human ANAPC11 protein, GST-tagged Wheat Germ GST
    Human ANAPC11-8868HCL Recombinant Human ANAPC11 293 Cell Lysate HEK293 N/A
    Human ANAPC11-8869HCL Recombinant Human ANAPC11 293 Cell Lysate HEK293 N/A
    Human ANAPC11-8870HCL Recombinant Human ANAPC11 293 Cell Lysate HEK293 N/A
    Human ANAPC11-9635H Recombinant Human ANAPC11, His-tagged E.coli His
    Mouse Anapc11-1620M Recombinant Mouse Anapc11 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque ANAPC11-318R Recombinant Rhesus monkey ANAPC11 Protein, His-tagged Mammalian Cell His
    Zebrafish ANAPC11-5685Z Recombinant Zebrafish ANAPC11 Mammalian Cell His

    anapc11 involved in several pathways and played different roles in them. We selected most pathways anapc11 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with anapc11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell cycle ARPP19; CDC25A; TERF2; ATM; TINF2; ORC4; KIF2A; RBBP8; CDK7; RAD9A
    Ubiquitin mediated proteolysis NEDD4; FBXO4; UBE2B; PIAS2; UBE2K; FBXW7; UBE2L3; UBE2N; FANCL; ANAPC7
    Progesterone-mediated oocyte maturation IGF1RB; CDK1; RPS6KA6; MAPK11; CPEB2; PIK3R2; PIK3CG; ANAPC7; INS; CCNB1
    HTLV-I infection STAT5B; PIK3R1; POLD1; NFKB1; FZD8; MAP2K4; TP53; RRAS2; BUB1B; Fzd4

    anapc11 has several biochemical functions, for example, cullin family protein binding, ubiquitin protein ligase activity, contributes_to ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by anapc11 itself. We selected most functions anapc11 had, and list some proteins which have the same functions with anapc11. You can find most of the proteins on our site.

    Function Related Protein
    cullin family protein binding DCUN1D2; DCUN1D1; DCUN1D4; CCDC22; RNF7; RBX1; TCHP; DCUN1D5; DCUN1D3; DCUN1D2A
    ubiquitin protein ligase activity TRIM59; FBXO40; RNF2; RNF139; HECTD2; UBR2; UBE2V1; UBE2S; FBXL22; PDZD4
    contributes_to ubiquitin-protein transferase activity KLHL32; KLHL17; ERCC8; BCOR; KCTD10; UBE2C; KLHL26; KLHL41B; KLHL21; GAN
    ubiquitin-ubiquitin ligase activity UBE2K; AMFR; STUB1; ANAPC11; PRPF19; UBE4B; UBOX5; RBX1; PPIL2
    zinc ion binding NANOS2; MARCH8; CA4A; RAG2; ZCCHC18; ZPR1; TRIM43B; RP9; ZDHHC18A; MORC1

    anapc11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with anapc11 here. Most of them are supplied by our site. Hope this information will be useful for your research of anapc11.

    CDC20; Cdc23; Cdc16; MAK; ZAP70; UBE2U; TRIM65; RNF111; MLKL; NKD2; CAPN11; CDC16

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