|Official Full Name||anaphase promoting complex subunit 11|
|Background||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.|
|Synonyms||ANAPC11; anaphase promoting complex subunit 11; APC11; Apc11p; MGC882; HSPC214; Anaphase-promoting complex subunit 11; Cyclosome subunit 11; Hepatocellular carcinoma-associated RING finger protein; APC11 anaphase promoting complex subunit 11 homolog; anaphase promoting complex subunit 11 (yeast APC11 homolog)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
anapc11 involved in several pathways and played different roles in them. We selected most pathways anapc11 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with anapc11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell cycle||ARPP19; CDC25A; TERF2; ATM; TINF2; ORC4; KIF2A; RBBP8; CDK7; RAD9A|
|Oocyte meiosis||AURKA; RPS6KA1; PRKACG; PPP3CB; RPS6KA3A; PTTG1; PPP2R5E; INSB; PPP3CCB; ANAPC5|
|Ubiquitin mediated proteolysis||NEDD4; FBXO4; UBE2B; PIAS2; UBE2K; FBXW7; UBE2L3; UBE2N; FANCL; ANAPC7|
|Progesterone-mediated oocyte maturation||IGF1RB; CDK1; RPS6KA6; MAPK11; CPEB2; PIK3R2; PIK3CG; ANAPC7; INS; CCNB1|
|HTLV-I infection||STAT5B; PIK3R1; POLD1; NFKB1; FZD8; MAP2K4; TP53; RRAS2; BUB1B; Fzd4|
anapc11 has several biochemical functions, for example, cullin family protein binding, ubiquitin protein ligase activity, contributes_to ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by anapc11 itself. We selected most functions anapc11 had, and list some proteins which have the same functions with anapc11. You can find most of the proteins on our site.
|cullin family protein binding||DCUN1D2; DCUN1D1; DCUN1D4; CCDC22; RNF7; RBX1; TCHP; DCUN1D5; DCUN1D3; DCUN1D2A|
|ubiquitin protein ligase activity||TRIM59; FBXO40; RNF2; RNF139; HECTD2; UBR2; UBE2V1; UBE2S; FBXL22; PDZD4|
|contributes_to ubiquitin-protein transferase activity||KLHL32; KLHL17; ERCC8; BCOR; KCTD10; UBE2C; KLHL26; KLHL41B; KLHL21; GAN|
|ubiquitin-ubiquitin ligase activity||UBE2K; AMFR; STUB1; ANAPC11; PRPF19; UBE4B; UBOX5; RBX1; PPIL2|
|zinc ion binding||NANOS2; MARCH8; CA4A; RAG2; ZCCHC18; ZPR1; TRIM43B; RP9; ZDHHC18A; MORC1|
anapc11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with anapc11 here. Most of them are supplied by our site. Hope this information will be useful for your research of anapc11.
CDC20; Cdc23; Cdc16; MAK; ZAP70; UBE2U; TRIM65; RNF111; MLKL; NKD2; CAPN11; CDC16