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Official Full Name ankyrin repeat domain 1 (cardiac muscle)
Background The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
Synonyms ANKRD1; ankyrin repeat domain 1 (cardiac muscle); ankyrin repeat domain-containing protein 1; ALRP; C 193; CARP; CVARP; MCARP; bA320F15.2; ANKR1_HUMAN; ANKRD 1; Ankyrin repeat domain containing protein 1; C193; Cardiac ankyrin repeat protein; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; OTTHUMP00000020084; C-193
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANKRD1-235H Recombinant Human ANKRD1 protein, T7/His-tagged E.coli T7/His
    Human ANKRD1-570H Recombinant Human ANKRD1 protein, GST-tagged Wheat Germ GST
    Human ANKRD1-586H Recombinant Human ANKRD1 Protein, His-tagged E.coli His
    Human ANKRD1-7150H Recombinant Human Ankyrin Repeat Domain 1 (Cardiac Muscle), His-tagged E.coli His
    Human ANKRD1-8858HCL Recombinant Human ANKRD1 293 Cell Lysate HEK293 N/A
    Human ANKRD1-9663H Recombinant Human ANKRD1, GST-tagged E.coli GST
    Mouse Ankrd1-587M Recombinant Mouse Ankrd1 Protein, His-tagged E.coli His
    Rat Ankrd1-588R Recombinant Rat Ankrd1 Protein, His/GST-tagged E.coli His/GST
    Rat ANKRD1-673R Recombinant Rat ANKRD1 Protein Mammalian Cell His
    Chicken ANKRD1-5975C Recombinant Chicken ANKRD1 Mammalian Cell His

    ankrd1 involved in several pathways and played different roles in them. We selected most pathways ankrd1 participated on our site, such as Fatty acid, triacylglycerol, and ketone body metabolism, Hypertrophy Model, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ankrd1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fatty acid, triacylglycerol, and ketone body metabolism ACOT11B; MED26; ACOT7; DECR1; CCNC; MTF1; ACOT9.1; CPT1B; SLC25A1A; AGPAT6
    Hypertrophy Model JUND; CYR61; IFRD1; MSTN; WDR1; MSTNB; ANKRD1; ADAM10A; MYOG; HBEGFB
    Metabolism SLC44A5B; NHLRC1; GCHFR; ARF3; LSM1; Alb; DCK; NFYAL; D2HGDH; MED6
    Metabolism of lipids and lipoproteins MED10; SLC25A20; GRHL1; MTP; STARD5; CETP; CYP2U1; SIN3B; SLC25A1; NFYAL
    PPARA activates gene expression MED26; GLIPR1; SREBF2; CTGF; MED25; MED29; MED8; GRHL1; MED23; PLIN2
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) MED6; CTGF; CDK19; MED29; MED22; GLIPR1; MED15; MED21; MED31; MED26

    ankrd1 has several biochemical functions, for example, DNA binding, R-SMAD binding, RNA polymerase II transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ankrd1 itself. We selected most functions ankrd1 had, and list some proteins which have the same functions with ankrd1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZNF473; POLR2K; SP110; TADA2A; RAD54B; ARNTL; TLX3B; ZFP28; ZNF471; KLF7
    RNA polymerase II transcription coactivator activity SMARCA4; MEF2A; MED12L; NEUROD1; SOX11; CITED2; SOX4; HYAL2; TBX20; NCOA1
    RNA polymerase II transcription factor binding TBX3; TEAD3; XBP1; GSK3B; GATA6; KDM1A; CREBBP; ZFPM2A; GFI1B; GATA2B
    histone deacetylase binding SIRT2; SOD3; SKOR2; HIST1H1B; ZMYND15; KAT2B; TOP2B; HOXA10; YWHAE; CEBPB
    p53 binding ZNF385C; MAPKAPK5; NUAK1; SMYD2; ANKRD1; GATA1; PTTG1IP; NTRK3; RCHY1; ZNF346
    protein binding MICALL2; SLC1A5; TESK2; INPP4B; BANK1; ARL11; ZNF124; VPS36; H2AFZ; PCDH18
    titin binding CAMK2D; CALM; CALM2; TRIM63; MYBPC1; ANKRD2; CALM1; ANKRD23; CAPN3; SLC14A2
    transcription corepressor activity HDAC9; MNT; ERF; TBL1X; JAZF1; NPAT; LOXL2; NR2F2; PIAS1; JUB

    ankrd1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ankrd1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ankrd1.


    Min, CK; Kwon, YJ; et al. Multiple Orientia tsutsugamushi Ankyrin Repeat Proteins Interact with SCF1 Ubiquitin Ligase Complex and Eukaryotic Elongation Factor 1 alpha. PLOS ONE 9:-(2014).
    Tiede, C; Tang, AAS; et al. Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. PROTEIN ENGINEERING DESIGN & SELECTION 27:145-155(2014).

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