ANKS1A
-
Official Full Name
ankyrin repeat and sterile alpha motif domain containing 1A
-
Overview
Ankyrin repeat and SAM domain-containing protein 1A is a protein that in humans is encoded by the ANKS1A gene. -
Synonyms
ANKS1A; ankyrin repeat and sterile alpha motif domain containing 1A; ANKS1, ankyrin repeat and SAM domain containing 1 , ankyrin repeat and sterile alpha motif domain containing 1; ankyrin repeat and SAM domain-containing protein 1A; KIAA0229; ANKS 1; ANKS 1A; ANKS1; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; ANS1A_HUMAN; MGC42354; Odin;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ANKS1A-611H | Recombinant Human ANKS1A protein, GST-tagged | Wheat Germ | GST |
|
|
| Human | ANKS1A-9677H | Recombinant Human ANKS1A, GST-tagged | E.coli | GST | 221-570a.a. | |
| Human | ANKS1-610H | Recombinant Human ANKS1 protein, GST-tagged | Wheat Germ | GST |
|
|
| Human | ANKS1A-83HCL | Recombinant Human ANKS1A cell lysate | N/A |
|
||
| Human | ANKS1A-1203HF | Recombinant Full Length Human ANKS1A Protein, GST-tagged | In Vitro Cell Free System | GST | 460 amino acids |
|
- Involved Pathway
- Protein Function
- Interacting Protein
- ANKS1A Related Articles
ANKS1A involved in several pathways and played different roles in them. We selected most pathways ANKS1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKS1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ANKS1A has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKS1A itself. We selected most functions ANKS1A had, and list some proteins which have the same functions with ANKS1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAP3K1;AGXT;VIPR1;AHNAK;CARD10;COPS7A;NAT8B;KIF6;SNX2 |
ANKS1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKS1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKS1A.
EGFR; YWHAG; PIK3R3; ERBB2; ERBB4; SFN; ARHGAP10; RB1; DOK3; NHLRC2; SMARCD1; TRIT1; RANBP3
- Q&As
- Reviews
Q&As (10)
Ask a questionMutations in the ANKS1A gene have been associated with neurodevelopmental disorders, including autism spectrum disorders and intellectual disabilities. These findings suggest a potential involvement of Anks1A in the pathogenesis of these conditions. However, further research is needed to understand the precise mechanisms underlying these associations.
Yes, Anks1A is implicated in various cellular processes beyond cytoskeletal organization. It is believed to have roles in intracellular signaling, protein-protein interactions, calcium signaling, and potentially synaptic development and function.
Current research on Anks1A protein focuses on understanding its role in cellular processes, its interactions with other proteins, and its potential involvement in neurodevelopmental disorders. Studies are being conducted to investigate the mechanisms of Anks1A function, its regulation, and its contribution to disease pathology.
Yes, Anks1A has a paralog called Anks1B (Ankyrin repeat and SAM domain-containing protein 1B) that shares high sequence similarity and similar domain architecture. Anks1B is also involved in cytoskeletal organization and protein-protein interactions, but its specific functions may differ from Anks1A.
Yes, mutations in the ANKS1A gene have been identified in individuals with neurodevelopmental disorders such as autism spectrum disorders and intellectual disabilities. These mutations can disrupt the normal function of Anks1A and suggest a potential link between ANKS1A variants and disease phenotypes.
Anks1A is primarily localized in the cytoplasm of the cell.
Anks1A protein contains several structural domains including multiple ankyrin repeats that are involved in protein-protein interactions, and a SAM domain (sterile alpha motif) that is implicated in protein-protein interactions and may have a role in intracellular signal transduction.
Yes, animal models such as knockout mice lacking the Anks1A gene have been generated to study its function. These models help researchers investigate the physiological effects of Anks1A loss and better understand its role in development and disease.
Anks1A contains several functional domains, including ankyrin repeats and SAM (sterile alpha motif) domains. Ankyrin repeats are responsible for protein-protein interactions, and SAM domains are involved in various cellular processes, including protein interactions and signal transduction.
Yes, several proteins have been reported to interact with Anks1A. Some of these interactors include TRPV4, p105, and Kank1/ANKS1B. These interactions suggest that Anks1A may play a role in calcium signaling, NF-κB pathway signaling, and cytoskeletal organization.
Customer Reviews (4)
Write a reviewThis protein has become an invaluable asset in my research, offering great versatility in its applications.
the ANKS1A protein stands out for its excellent quality, exceptional technical support, and wide range of applications.
It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.
Its robust performance has significantly accelerated my research progress and contributed to the advancement of my scientific understanding.
Ask a Question for All ANKS1A Products
Required fields are marked with *
My Review for All ANKS1A Products
Required fields are marked with *
