AP2A2
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Official Full Name
adaptor-related protein complex 2, alpha 2 subunit -
Synonyms
AP2A2;adaptor-related protein complex 2, alpha 2 subunit;ADTAB, CLAPA2;AP-2 complex subunit alpha-2;adaptin;alpha B;alpha adaptin C;Huntingtin interacting protein J;clathrin associated/assembly/adaptor protein;large;alpha 2;DKFZP564D1864;HIP9;HYPJ;KIAA0899;alpha2-adaptin;adaptin, alpha B;huntingtin yeast partner J;100 kDa coated vesicle protein C;huntingtin-interacting protein 9;alpha-adaptin C;Huntingtin interacting protein J;clathrin assembly protein complex 2 alpha-C large chain;plasma membrane adaptor HA2/AP2 adaptin alpha C subunit;clathrin-associated/assembly/adaptor protein, large, alpha 2;ADTAB;HIP-9;CLAPA2;FLJ37177
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AP2A2-9715H | Recombinant Human AP2A2, His-tagged | E.coli | Human | His | 590-939a.a. | |
| AP2A2-1739M | Recombinant Mouse AP2A2 Protein | Mammalian Cells | Mouse | His |
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| AP2A2-2111C | Recombinant Chicken AP2A2 | Mammalian Cells | Chicken | His |
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| Ap2a2-3531R | Recombinant Rat Ap2a2, His-tagged | E.Coli/Yeast | Rat | His | 938 |
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| AP2A2-3532H | Recombinant Human AP2A2, His-tagged | E.Coli/Yeast | Human | His | 940 |
|
| AP2A2-8816HCL | Recombinant Human AP2A2 293 Cell Lysate | HEK293 | Human | Non |
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| AP2A2-601M | Recombinant Mouse AP2A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| AP2A2-601M-B | Recombinant Mouse AP2A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
AP2A2 involved in several pathways and played different roles in them. We selected most pathways AP2A2 participated on our site, such as Adaptive Immune System,Axon guidance,Beta-catenin independent WNT signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | KCNQ2,CHL1,SPNA2,SEMA4A,NRG3,NTN4,CD24,ROBO1,SCN2B,ARPC1A |
| EGFR downregulation | SPRY1,AP2S1,STAM2,AP2B1,SPRY2,PTPRK,AP2M1,AP2A1 |
| EPH-ephrin mediated repulsion of cells | EFNB3B,EPHA10,EPHB4B,EFNB3,EPHA4A,EFNB1,EPHA2,EPHB4A,EFNA1,EFNA1B |
| Developmental Biology | SCN8A,CNTN1,CNKSR1,DUSP4,DPYSL5A,EFNA2A,SCN2A,MED21,EFNB3B,CACNG2 |
| Disease | APOBEC3G,OS9,KREMEN1,GCKR,RCC1,OPN1MW,RPL35,DERL2,PACS1,NUPL2 |
| Beta-catenin independent WNT signaling | CLTA,ITPR2,PRICKLE1,AP2A1,PRICKLE1B,MOV10,ROR1,AGO3,AP2S1,ROR2 |
| EPH-Ephrin signaling | EFNA3B,ACTR2B,EFNB1,EFNA2A,AP2B1,EPHA2A,ARHGEF28,EFNB2A,ARPC4,EPHA4A |
| Adaptive Immune System | SIGLEC10,Mill2,SIGLEC6,SPSB1,AP1S3A,RAP1GAP2,DNM1,ITK,MGC174155,AGO2 |
Protein Function
AP2A2 has several biochemical functions, for example, contributes_to clathrin adaptor activity,lipid binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by AP2A2 itself. We selected most functions AP2A2 had, and list some proteins which have the same functions with AP2A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to clathrin adaptor activity | AP2B1,AP2A1,AP2S1,AP2M1 |
| protein binding | UBTD1,KANSL2,AICDA,FAM54B,FGD5,NR1D2,KLRC4-KLRK1,ZRANB1,ITGA3,CBL |
| lipid binding | FABP10A,SH3GL2,FABP7B,CYP21A1,PPARD,RBP2A,PITPNA,BPIFA3,FABP6,FAM123C |
| protein kinase binding | TRIM22,PPP1R12C,SYN1,SHC3,PLK1,CCNK,PRKAG1,DNM1,VRK2,E2F1 |
| molecular_function | RPRML,KRTAP5-1,TSTD2,SPINT4,GLT25D2,ABHD2,TMCC3,ZNF664,C11orf58,GAGE2C |
| protein complex binding | CDK5RAP1,PDZK1,NFYB,NFKBIA,NRAS,PPARA,DISC1,WRN,ADRB2,PPP1R9B |
| protein transporter activity | SEC62,C11orf73,XPO6,CALCR,AP1B1,AP1S3B,PGAP2,CALCRL,VPS26B,ITGB1BP1 |
Interacting Protein
AP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP2A2.
SHC1;AP2M1;Dab2;Kcnj11;HTT;SMAD1;katG;hflK;q81lw1_bacan;y2173_bacan;vacB;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;EGFR
AP2A2 Related Signal Pathway
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References
- Stratta, P; Merlotti, G; et al. Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population. NEPHROLOGY DIALYSIS TRANSPLANTATION 29:1902-1909(2014).
- Upadhyay, RD; Kumar, AV; et al. Estrogen Effects on Actin Cytoskeletal and Endocytic Proteins Associated With Tubulobulbar Complex Disruption in Rat Testes. REPRODUCTIVE SCIENCES 20:1162-1174(2013).
