apoa4

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apoa4

Official Full Name apolipoprotein A-IV
Background Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008]
Synonyms APOA4; apolipoprotein A-IV; apo-AIV; apoA-IV; apolipoprotein A4;
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Human Plasma
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • S
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse APOA4-1332M Recombinant Mouse APOA4 Protein (21-395 aa), His-tagged Yeast His
    Human APOA4-2470H Recombinant Human APOA4 Protein (21-396 aa), His-tagged Yeast His
    Human APOA4-2037H Recombinant Human APOA4 protein, His & GST-tagged E.coli His/GST
    Human APOA4-30H Recombinant Human APOA4, His-tagged HEK293 His
    Human ApoA4-68H Native Human Apolipoprotein AIV Human Plasma N/A
    Human APOA4-692H Recombinant Human APOA4 protein, GST-tagged Wheat Germ GST
    Human APOA4-766H Recombinant Human APOA4 Protein, His-tagged HEK293 His
    Human APOA4-8788HCL Recombinant Human APOA4 293 Cell Lysate HEK293 N/A
    Human APOA4-9749H Recombinant Human APOA4, GST-tagged E.coli GST
    Mouse APOA4-1782M Recombinant Mouse APOA4 Protein Mammalian Cell His
    Mouse Apoa4-2038M Recombinant Mouse Apoa4 protein, His & S-tagged E.coli His/S
    Mouse Apoa4-2039M Recombinant Mouse Apoa4 protein, His & S-tagged E.coli His/S
    Rat APOA4-719R Recombinant Rat APOA4 Protein Mammalian Cell His
    Rat Apoa4-720R Recombinant Rat Apoa4 protein, His/GST-tagged E.coli His/GST
    Chicken APOA4-6498C Recombinant Chicken APOA4 Mammalian Cell His
    Cattle APOA4-2036C Recombinant Cattle APOA4 protein, His & T7-tagged E.coli His/T7
    Pig APOA4-2040P Recombinant Pig APOA4 protein, His-tagged E.coli His
    Pig APOA4-3567P Recombinant Pig APOA4, His-tagged E.Coli or Yeast His

    apoa4 involved in several pathways and played different roles in them. We selected most pathways apoa4 participated on our site, such as Fat digestion and absorption, Vitamin digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with apoa4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fat digestion and absorption MOGAT3; MOGAT2; SCARB1; PLA2G10; APOA4; PNLIPRP2; SLC27A4; GOT2; MTTP; PPAP2A
    Vitamin digestion and absorption CUBN; SLC52A3; SLC46A1; SLC19A2; LMBRD1; SLC23A1; PNLIP; SLC5A6; APOA4; FOLH1

    apoa4 has several biochemical functions, for example, antioxidant activity, cholesterol binding, cholesterol transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by apoa4 itself. We selected most functions apoa4 had, and list some proteins which have the same functions with apoa4. You can find most of the proteins on our site.

    Function Related Protein
    antioxidant activity S100A9; APOE; APOA4; PRDX5; SELS; CAT; APOM; MT3; UBIAD1; FABP1
    cholesterol binding TSPO; NR1H3; OSBPL1A; TSPO2; OSBPL7; APOA4B.1; OSBPL2; PROM2; APOA4A; APOA5
    cholesterol transporter activity APOA4B.2; ABCA7; APOA1; APOA4; ABCA4; APOEB; ABCA1; ABCA1B; ABCA4A; CETP
    copper ion binding AOC2; P2RX2; CCC2; TYR; F5; AOC3; LOXL3B; COMMD1; CP; F8
    lipid binding RASGRP1; SH3GL2; AMER2; PITPNM3; PACSIN3; APOEA; BPIFB7; SH3GL3; CPTP; ACBD6
    lipid transporter activity VTG5; APOC4; APOA4; VTG4; APOM; VTG6; APOE; RFT1; MTTP; CETP
    phosphatidylcholine binding APOA4B.2; CETP; NF1; ESYT2; CHMP3; APOA2; APOA4A; ALDOB; APOA4B.1; GPR119
    phosphatidylcholine-sterol O-acyltransferase activator activity APOA4B.2; APOEB; APOA4; APOA2; APOA4B.1; APOA1A; APOA5; APOA1; APOA4A; APOC1
    protein binding a; MEN1; CDCP1; THEMIS2; POU2F3; HBZ; ACVRL1; RINT1; ALX1; ZNF652
    protein homodimerization activity RABEP1; NR6A1A; RPE; GABPB2; C9orf142; FAM109A; C6orf108; IMPA1; WHRN; DPP4

    apoa4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with apoa4 here. Most of them are supplied by our site. Hope this information will be useful for your research of apoa4.

    NR1D1; d-mannose; g6pc_human_gene; ALB

    Tokuhara, D; Nochi, T; et al. Specific Expression of Apolipoprotein A-IV in the Follicle-Associated Epithelium of the Small Intestine. DIGESTIVE DISEASES AND SCIENCES 59:2682-2692(2014).
    Zhao, HH; Yang, F; et al. Label Free Proteome Analysis of Plasma from Unstable Angina with Blood Stasis Syndrome Patients. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 31:285-292(2010).

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