ARF1 Protein

September 27-30, 2022

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ARF1

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ARF1

Official Full Name ADP-ribosylation factor 1
Background ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms ARF1; ADP-ribosylation factor 1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His-GST & Myc
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARF1-224H Recombinant Human ARF1, His-tagged E.coli His
    Human ARF1-2769H Recombinant Human ADP-ribosylation Factor 1, His-tagged E.coli His
    Human ARF1-744H Recombinant Human ARF1 protein, GST-tagged Wheat Germ GST
    Human ARF1-9799H Recombinant Human ARF1, GST-tagged E.coli GST
    Mouse ARF1-1837M Recombinant Mouse ARF1 Protein Mammalian Cell His
    Rat Arf1-3205R Recombinant Rat Arf1, His-tagged E.Coli or Yeast His
    Rat ARF1-747R Recombinant Rat ARF1 Protein Mammalian Cell His
    Cynomolgus Monkey ARF1-308C Recombinant Cynomolgus ARF1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ARF1-378R Recombinant Rhesus monkey ARF1 Protein, His-tagged Mammalian Cell His
    Chicken ARF1-1496C Recombinant Chicken ARF1 Mammalian Cell His
    Zebrafish ARF1-11499Z Recombinant Zebrafish ARF1 Mammalian Cell His
    Human ARF1-8760HCL Recombinant Human ARF1 293 Cell Lysate HEK293 N/A
    Human ARF1-8761HCL Recombinant Human ARF1 293 Cell Lysate HEK293 N/A
    Human ARF1-2544H Recombinant Human ARF1 protein, His-GST & Myc-tagged E.coli His-GST & Myc
    Human ARF1-1938H Recombinant Human ARF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ARF1-506H Recombinant Human ARF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Arf1-634M Recombinant Mouse Arf1 Protein, MYC/DDK-tagged HEK293T MYC/DDK

    ARF1 involved in several pathways and played different roles in them. We selected most pathways ARF1 participated on our site, such as Adaptive Immune System, Arf1 pathway, Arf6 downstream pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System AP2S1; CTSL1; PJA2; KIF11; LILRA1; MGC174155; TRIM39; AP1G1; CD96; TRIM11
    Arf1 pathway ARF1; USO1; ARFIP2; CLTB; AP2M1; CLTA; AP2A1
    Arf6 downstream pathway ARF1
    COPI Mediated Transport ARCN1; COPE; ARF1; COPG; TERFA; COPB1; COPZ1; COPB2; ARCN1B; ARCN1A
    Cell cycle CUL1; CCNH; YWHAQ; FOXM1; ANKLE2; PDS5A; RAD21B; ORC3L; UBE2V2; TMPO
    Class I PI3K signaling events ADAP1; ITK; BLK; ARF1; PLEKHA1
    Clathrin derived vesicle budding CLVS1; AP1G1; APPB; YIPF6; NAPAB; PLDN; CPD; SNAPIN; TGOLN2; SH3D19
    Disease PPIAL4A; ARF1; CHMP4C; EPM2A; TLR10; KERA; COBRA1; AP2S1; AP1B1; GPC6

    ARF1 has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARF1 itself. We selected most functions ARF1 had, and list some proteins which have the same functions with ARF1. You can find most of the proteins on our site.

    Function Related Protein
    GDP binding RAB12; RAB7; RAB3B; RAB11B; RAB28; GEM; ARL8B; ARF1; RAB14; RAB35
    GTP binding ARF3; RHEBL1; SEPT12; ARF3B; GBP4; RHOAC; RAB30; RNGTT; ARFRP1; MXA
    GTPase activity RND3; RAB14; GBP5; RAB32A; GTPBP10; TUBA8L2; RHOD; SEPT5; RAB40B; EEF1A1
    magnesium ion binding RPS6KA6; PGM3; NCS1; TREX2; TDP2; MAP3K6; NT5C3L; PCK1; ALPI; ATP8B3
    phospholipase D activator activity ARF1
    poly(A) RNA binding PRR3; RTF1; RPS16; SRP19; SF3B14; FASTKD3; EXOSC10; FNDC3A; MRTO4; CHD2
    protein binding HNF1B; TRIM3; SNRNP27; SPINLW1; TRMT112; KLB; PPP1R2P3; RSU1; CORO6; PPP2R5C
    receptor signaling protein activity DCLK1; TRAIP; BAG4; NSMAF; DAXX; RGS14A; ARAF; DOK5; RAF1A; FCGR1A

    ARF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARF1.

    CYTH2; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; SPAG9; ASAP1; GEA1; Asap1; Asap1; Kif1c; MYC; Bach1; AP1B1; Proser1

    Richards, AL; Soares-Martins, JAP; et al. Generation of Unique Poliovirus RNA Replication Organelles. MBIO 5:-(2014).
    Hehnly, H; Xu, WD; et al. Cdc42 Regulates Microtubule-Dependent Golgi Positioning. TRAFFIC 11:1067-1078(2010).

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