Recombinant Mouse Arf1 Protein, MYC/DDK-tagged
Cat.No. : | Arf1-634M |
Product Overview : | Purified recombinant protein of full-length mouse ADP-ribosylation factor 1 (Arf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD). |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 20.7 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Arf1 ADP-ribosylation factor 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Arf1 |
Synonyms : | Arf1; ADP-ribosylation factor 1; ADP-ribosylation factor 1 |
Gene ID : | 11840 |
mRNA Refseq : | NM_001130408 |
Protein Refseq : | NP_001123880 |
UniProt ID : | P84078 |
Products Types
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ARF1-658M | Recombinant Mouse ARF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ARF1-224H | Recombinant Human ARF1 protein(Met1-Lys181), His-tagged | +Inquiry |
ARF1-58C | Recombinant Cynomolgus Monkey ARF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ARF1-8761HCL | Recombinant Human ARF1 293 Cell Lysate | +Inquiry |
ARF1-8760HCL | Recombinant Human ARF1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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