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Official Full Name Rho guanine nucleotide exchange factor (GEF) 10
Background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals.
Synonyms ARHGEF10; Rho guanine nucleotide exchange factor (GEF) 10; rho guanine nucleotide exchange factor 10; Gef10; KIAA0294; ARHGA_HUMAN; DKFZp686H0726; MGC131664
    • Species :
    • Human
    • Source :
    • E.coli
    • Wheat Germ
    • Tag :
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGEF10-116HCL Recombinant Human ARHGEF10 cell lysate N/A
    Human ARHGEF10-778H Recombinant Human ARHGEF10 protein, GST-tagged Wheat Germ GST
    Human ARHGEF10-779H Recombinant Human ARHGEF10 protein, GST-tagged Wheat Germ GST
    Human ARHGEF10-9832H Recombinant Human ARHGEF10, GST-tagged E.coli GST

    arhgef10 involved in several pathways and played different roles in them. We selected most pathways arhgef10 participated on our site, such as Regulation of RhoA activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgef10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of RhoA activity ARHGEF15; ARHGEF18; FARP1; NET1; ARHGEF10L; ARAP1; ARHGEF28; DEF6; ABR; ARHGEF25

    arhgef10 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity, kinesin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgef10 itself. We selected most functions arhgef10 had, and list some proteins which have the same functions with arhgef10. You can find most of the proteins on our site.

    Function Related Protein
    Rho guanyl-nucleotide exchange factor activity ARHGEF3L; PLEKHG4; ARHGEF19; ARHGEF33; FARP2; ARHGEF18A; TIAM2; ARHGEF9B; PLEKHG6; ECT2
    kinesin binding IFT88; ACTB; NUP62; KTN1; KIFAP3A; KIFAP3; TOR1A; FAM83D; GOLSYN; PIFO
    protein binding EZR; PALM; EEF1B2; RAD1; PRKCB; XK; CA; AMBP; EIF4H; POP5

    arhgef10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgef10 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgef10.

    KIF3B; WDR48

    Huang, IH; Hsiao, CT; et al. GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment. JOURNAL OF CELL SCIENCE 127:4186-4200(2014).
    Martin, E; Harel, S; et al. pix-1 Controls Early Elongation in Parallel with mel-11 and let-502 in Caenorhabditis elegans. PLOS ONE 9:-(2014).

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