Recombinant Full Length Human ARHGEF10 Protein, GST-tagged

• Cat.No.: ARHGEF10-1144HF
• Product Overview: Human ARHGEF10 full-length ORF ( AAH40474.1, 1 a.a. - 380 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 70.1 kDa
• Protein Length: 380 amino acids
• AA Sequence: MENPEEAIYD DVPRENSDSE PDEMIYDDVE NGDEGGNSSL EYGWSSSEFE SYEEQSDSEC KNGIPRSFLR SNHKKQMQKL VKAAKDGTKD GLERTRAAVK RGRSFIRTKS LIAQDHRSSL EEEQNLFIDV DCKHPEAILT PMPEGLSQQQ VVRRYILGSV VDSEKNYVDA LKRILEQYEK PLSEMEPKVL SERKLKTVFY RVKEILQCHS LFQIALASRV SEWDSVEMIG VVFVASFSKS MVLDAYSEYV NNFSTAVAVL KKTCATKPAF LEFLKQEQEA SPDRTTLYSL MMKPIQRFPQ FILLLQDMLK NTSKGHPDRL PLQMALTELE TLAEKLNERK RDADQRCEVK QIAKAINERY LNKVERGFLQ LYSKIIFALC
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 [ Homo sapiens ]
• Official Symbol: ARHGEF10
• Synonyms: ARHGEF10; Rho guanine nucleotide exchange factor (GEF) 10; rho guanine nucleotide exchange factor 10; Gef10; KIAA0294; GEF10; MGC131664; DKFZp686H0726
• Gene ID: 9639
• mRNA Refseq: NM_014629
• Protein Refseq: NP_055444
• MIM: 608136
• UniProt ID: O15013