| Official Full Name | Rho guanine nucleotide exchange factor (GEF) 16 |
| Background | Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. |
| Synonyms | ARHGEF16; Rho guanine nucleotide exchange factor (GEF) 16; rho guanine nucleotide exchange factor 16; GEF16; NBR; putative neuroblastoma protein; ARHGEF 16; Rho guanine exchange factor (GEF) 16; ephexin-4 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
arhgef16 involved in several pathways and played different roles in them. We selected most pathways arhgef16 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE, G alpha (12/13) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgef16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell death signalling via NRAGE, NRIF and NADE | DCLRE1B; ITSN1; ARHGEF16; ECT2; ARHGAP4A; FGD2; KALRN; MCF2L; ARHGEF17; NET1 |
| G alpha (12/13) signalling events | ARHGEF16; GNA13B; RHOB; OBSCN; ABR; ARHGEF17; NET1; ARHGEF18; ARHGEF3; AKAP13 |
| GPCR downstream signaling | CCL19A.2; OR52B4; GPR132; RASGRP2; ARHGAP4A; TAS2R3; CRHR2; ANXA1B; LPAR1; SSTR3 |
| NRAGE signals death through JNK | ABR; ARHGEF3; AATF; AKAP13; ARHGEF1A; MCF2L; ARHGEF9; ARHGEF18A; TIAM2; ECT2 |
| Rho GTPase cycle | DEPDC7; ABR; FGD4; ARHGAP29B; CHN1; ARHGAP12; ARHGAP29; RHOT2; ARHGAP18; ARHGAP36 |
| Signal Transduction | AES; MDKB; OBSCN; NPHP4; USP34; RHOV; ASH2L; SST; BCL9; WIPF2 |
| Signaling by GPCR | SST1.1; OR52J3; OPN4A; NTS; CXCL11.8; PLEKHG2; GAL; VIP; ARHGEF16; HEBP1 |
| Signaling by Rho GTPases | ARHGAP28; ARAP1; RHOJ; CIT; ROPN1; ARHGAP29; TAGAP1; RHOT1B; ARHGAP12; IQGAP3 |
arhgef16 has several biochemical functions, for example, PDZ domain binding, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgef16 itself. We selected most functions arhgef16 had, and list some proteins which have the same functions with arhgef16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | GNG5; ACOX1; LRP2; GRIK5; PDZK1; ATP2B1; CRIPT; FZD3; CXADR; NKD1 |
| Rho GTPase binding | DIAPH3; LRRK2; DIAPH1; ARHGEF16; ROCK2B; FLNA; INF2; ROCK2A; DOCK9; IQGAP3 |
| Rho guanyl-nucleotide exchange factor activity | ABR; ARHGEF11; FGD3; RASGRF2B; ARHGEF16; ARHGEF2; DCLRE1B; ARHGEF39; ARHGEF40; ARHGEF7A |
| protein binding | POR; WBP4; NAT10; NGFR; ILK; RPL7A; SSX1; ADAMTSL5; IKZF3; C7orf50 |
| receptor tyrosine kinase binding | TRP53; NRG1; ANGPT2A; PTPN11; PTPN1; PCNA; ANGPT4; ANGPT1; ANGPT2; ELMO2 |
arhgef16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgef16 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgef16.
TFG; MAPK1IP1L; TFG; SFN; YWHAG; YWHAZ
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