ARHGEF16

  • Official Full Name

    Rho guanine nucleotide exchange factor (GEF) 16

  • Overview

    Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.

  • Synonyms

    ARHGEF16;Rho guanine nucleotide exchange factor (GEF) 16;rho guanine nucleotide exchange factor 16;GEF16;NBR;putative neuroblastoma protein;ARHGEF 16;Rho guanine exchange factor (GEF) 16;ephexin-4

Recombinant Proteins

  • Mouse
  • Human
  • Zebrafish
  • Mammalian Cells
  • E.coli
  • Wheat Germ
  • In Vitro Cell Free System
  • HEK293
  • His
  • T7
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARHGEF16-1891M Recombinant Mouse ARHGEF16 Protein Mammalian Cells Mouse His
ARHGEF16-2984H Recombinant Human ARHGEF16, T7-tagged E.coli Human T7 1-421 a.a.
ARHGEF16-6671Z Recombinant Zebrafish ARHGEF16 Mammalian Cells Zebrafish His
ARHGEF16-782H Recombinant Human ARHGEF16 protein, GST-tagged Wheat Germ Human GST
ARHGEF16-117HCL Recombinant Human ARHGEF16 cell lysate Human Non
ARHGEF16-1226HF Recombinant Full Length Human ARHGEF16 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 421 amino acids
ARHGEF16-2696H Recombinant Human ARHGEF16 Protein, His-tagged E.coli Human His
ARHGEF16-692M Recombinant Mouse ARHGEF16 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ARHGEF16-692M-B Recombinant Mouse ARHGEF16 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ARHGEF16 involved in several pathways and played different roles in them. We selected most pathways ARHGEF16 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGEF16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signaling by GPCR XK,OR10A5,GPR77,CCL35.1,RGS12,PENKA,CXCR7B,NET1,ADCYAP1B,EDNRAB
    NRAGE signals death through JNK ARHGEF18A,DCLRE1B,FGD2,AKAP13,FGD4A,ARHGAP4A,ECT2,ARHGAP4,NET1,MCF2L
    Rho GTPase cycle RHOT1A,OPHN1,FGD2,ARHGAP4A,ARHGAP1,ARHGEF1A,ARAP2,TAGAP,ARHGAP12B,CHN1
    Signaling by Rho GTPases GMIP,RHOF,RHPN1,RHOUA,ARHGAP28,IQGAP3,ARHGAP20,ARHGAP31,PRC1B,GDI1
    Signal Transduction PDK3,LRP10,RAMP1,OR7D2,WLS,ADAM12,PTHRP2,GDI1,DACT1,STARD13
    Cell death signalling via NRAGE, NRIF and NADE FGD2,ARHGEF9,AKAP13,CASP2,ABR,ITGB3BP,DCLRE1B,ARHGEF18A,KALRNB,OBSCN
    GPCR downstream signaling PYY,ARHGEF18,PLEKHG2,S1PR3,OPN5,EDN3,RGS17,OBSCN,ADRA2A,PENKB
    G alpha (12/13) signalling events FGD4,FGD4A,TRIO,ARHGEF18,MCF2L,AKAP13,ITSN1,TIAM2,NET1,OBSCN

    Protein Function

    ARHGEF16 has several biochemical functions, for example, PDZ domain binding,Rho GTPase binding,Rho guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGEF16 itself. We selected most functions ARHGEF16 had, and list some proteins which have the same functions with ARHGEF16. You can find most of the proteins on our site.

    Function Related Protein
    receptor tyrosine kinase binding DOCK4,PLCG1,PIK3R2,FLT3LG,TP53,PTPN2,LRP4,PTPN1,GAS6,TRP53
    PDZ domain binding FZD2,LPAR2,ATP2B1,DLC,GRIK2,GNG12,CADM1,BAIAP2,ACCN3,PTENA
    Rho guanyl-nucleotide exchange factor activity ABR,BCR,ARHGEF18,ARHGEF7B,KALRNB,FGD3,MCF2L,DNMBP,FGD,ITSN1
    protein binding DYRK4,QRICH1,PRPF19,ITGB3BP,PHC2,FRMD6,ROPN1,PRKRIP1,TAP2,NAA16
    Rho GTPase binding DIAPH3,ANTXR2A,DIAP1,LRRK2,KIF3B,DIAP3,ROCK2B,FLNA,DOCK11,FMNL2

    Interacting Protein

    ARHGEF16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGEF16 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGEF16.

    TFG;MAPK1IP1L;TFG;SFN;YWHAG;YWHAZ

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