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Official Full Name ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Background This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms ASAP1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; DDEF1, development and differentiation enhancing factor 1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; centaurin; beta 4; CENTB4; KIAA1249; PAP; ZG14P; DEF-1; cent
    • Species :
    • Bovine
    • Human
    • Mouse
    • Rat
    • Source :
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASAP1-8668HCL Recombinant Human ASAP1 293 Cell Lysate HEK293 N/A
    Human ASAP1-881H Recombinant Human ASAP1 protein, GST-tagged Wheat Germ GST
    Mouse ASAP1-2002M Recombinant Mouse ASAP1 Protein Mammalian Cell His
    Rat ASAP1-816R Recombinant Rat ASAP1 Protein Mammalian Cell His
    Bovine ASAP1-3617B Recombinant Bovine ASAP1, His-tagged E.Coli or Yeast His

    asap1 involved in several pathways and played different roles in them. We selected most pathways asap1 participated on our site, such as Endocytosis, Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with asap1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fc gamma R-mediated phagocytosis PPAP2A; AKT1; MAPK1; VAV2; MARCKS; CFL1; PIP5K1B; PIK3CD; MARCKSL1; FCGR2B

    asap1 has several biochemical functions, for example, GTPase activator activity, metal ion binding, phosphatidylinositol-3,4,5-trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by asap1 itself. We selected most functions asap1 had, and list some proteins which have the same functions with asap1. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity SGSM3; GDI1; STARD13; TBC1D10B; ARAP1; AXIN1; GRTP1; EVI5L; TIAM2; BNIP2
    metal ion binding PRDM8B; TRIM35-24; ZNF654; PAN3; TSSK1; ZFC3H1; ZRSR2; PM20D1.2; SMYD1A; CYP2X7
    phosphatidylinositol-3,4,5-trisphosphate binding COMMD1; ARAP3; RAG2; ZFYVE1; ZFYVE16; KIF16B; GBF1; FERMT2; INPPL1; CYTH3
    phosphatidylinositol-4,5-bisphosphate binding PFN2; MYO1G; LDLRAP1; SNX21; TWF1; MARK1; JPH2; FAM123A; ANXA2; STXBP6L
    protein binding APOOL; MOBP; REXO1L1; ARID3B; MIEF1; RCAN3; TXK; TMEM106C; PCGF2; STK24

    asap1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with asap1 here. Most of them are supplied by our site. Hope this information will be useful for your research of asap1.


    Schwenteit, J; Bogdanovic, X; et al. Toxoid construction of AsaP1, a lethal toxic aspzincin metalloendopeptidase of Aeromonas salmonicida subsp achromogenes, and studies of its activity and processing. VETERINARY MICROBIOLOGY 162:687-694(2013).
    Li, HH; Li, Q; et al. WNT1-Inducible Signaling Pathway Protein 1 Contributes to Ventilator-Induced Lung Injury. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 47:528-535(2012).

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