ASB9
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Official Full Name
ankyrin repeat and SOCS box containing 9
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Overview
This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ASB9; ankyrin repeat and SOCS box containing 9; ankyrin repeat and SOCS box protein 9; DKFZP564L0862; FLJ20636; MGC4954; ASB-9; ankyrin repeat and SOCS box-containing 9; ankyrin repeat and suppressor of cytokine signaling box protein 9;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ASB9-9921H | Recombinant Human ASB9, GST-tagged | E.coli | GST | 1-252a.a. | |
| Human | ASB9-898H | Recombinant Human ASB9 protein, GST-tagged | Wheat Germ | GST |
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| Human | ASB9-8657HCL | Recombinant Human ASB9 293 Cell Lysate | HEK293 | N/A |
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| Human | ASB9-8658HCL | Recombinant Human ASB9 293 Cell Lysate | HEK293 | N/A |
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| Human | ASB9-1364HF | Recombinant Full Length Human ASB9 Protein, GST-tagged | In Vitro Cell Free System | GST | 252 amino acids |
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| Human | ASB9-5738H | Recombinant Human ASB9 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | ASB9-2021M | Recombinant Mouse ASB9 Protein | Mammalian Cell | His |
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| Mouse | Asb9-1736M | Recombinant Mouse Asb9 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | ASB9-781M | Recombinant Mouse ASB9 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ASB9-781M-B | Recombinant Mouse ASB9 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | ASB9-1409C | Recombinant Chicken ASB9 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ASB9 Related Articles
ASB9 involved in several pathways and played different roles in them. We selected most pathways ASB9 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | SIGLEC12;LRR1;TREML2;FBXO27;KLB;CTSL2;DZIP3;Mill2;KLHL20 |
| Antigen processing: Ubiquitination & | KLHL20;FBXO3;DZIP3;SPSB4;UBE2U;FBXO27;DTX3L;PJA1;RNF19B |
| Proteasome degradation | MKRN1;NPEPPS;RNF4;UBE2F;LRSAM1;SPSB2;ASB9;UBR2;RNF138 |
| Class I MHC mediated antigen processing & | TRIM39;ARIH2;CD207;CMTM2A;CTSL1;LRSAM1;UBR1;UBE2E3;SPSB2 |
| presentation | TPP2;TRIM39;BLMH;ASB8;RBCK1;LRRC41;UBE2F;ASB7;ASB17 |
| Immune System | IFI16;KIF3C;RNF123;NPEPPS;BAIAP2;TRIM9;SH3RF1;SPSB4;CLEC2H |
ASB9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB9 itself. We selected most functions ASB9 had, and list some proteins which have the same functions with ASB9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ATRNL1;SARM1;MCM6;DPYD;BBS12;TRIM54;CXXC11;SETDB2;PIK3R1 |
ASB9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB9.
CKB; CKM; HIF1AN; HEL-S-29; CRK; PLCG2; Tceb1
- Q&As
- Reviews
Q&As (4)
Ask a questionThe precise role of ASB9 in cellular processes such as cell proliferation or differentiation is not well-established. However, its involvement in protein degradation suggests it may influence various aspects of cellular homeostasis.
Currently, there are no specific diseases directly associated with ASB9. However, dysregulation of protein degradation pathways, in which ASB9 is involved, can contribute to various pathological conditions.
ASB9 is primarily localized in the cytoplasm of cells. However, it may also shuttle between the cytoplasm and nucleus, depending on specific cellular signaling events.
ASB9 interacts with several proteins, such as Cullin-5 (CUL5) and Elongin BC complex, to form an E3 ubiquitin-protein ligase complex. It also interacts with specific target substrates for degradation.
Customer Reviews (3)
Write a reviewIts ability to bind to negatively charged phospholipids, particularly during blood clot formation, has made it invaluable for in vitro and in vivo investigations of hemostatic mechanisms.
The manufacturer of ASB9 protein plays a crucial role in supporting my research endeavors.
the ASB9 protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.
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