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ASIC1

  • Official Full Name

    acid-sensing (proton-gated) ion channel 1

  • Synonyms

    ASIC1;acid-sensing (proton-gated) ion channel 1;100;ENSG00000110881;ASIC;ACCN2;BNaC2;12q12;acid-sensing ion channel 1;acid-sensing ion channel 1;brain sodium channel 2;acid-sensing ion channel 1a protein;amiloride-sensitive cation channel 2, neuronal;Cation channel, amiloride-sensitive, neuronal, 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mamanlian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ASIC1-3071H Recombinant Human ASIC1, His-tagged E.Coli or Yeast His 528
Human ASIC1-152H Recombinant Human ACCN2 Protein, GST-Tagged Wheat Germ GST
Human ASIC1-151H Recombinant Human ASIC1 Protein, GST-Tagged Wheat Germ GST
Human ASIC1-32H Recombinant Human ASIC1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ASIC1-9101HCL Recombinant Human ACCN2 293 Cell Lysate HEK293 N/A
Human ASIC1-9102HCL Recombinant Human ACCN2 293 Cell Lysate HEK293 N/A
Human ASIC1-5523HFL Recombinant Full Length Human ASIC1 protein, Flag-tagged Mamanlian cells Flag
Human ASIC1-4187H Recombinant Human ASIC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ASIC117343C Recombinant Human ASIC1 (chicken) (26-463) Protein Insect Cell
Human ASIC1-767HF Recombinant Full Length Human ASIC1 Protein, GST-tagged In Vitro Cell Free System GST 528 amino acids
Mouse Asic1-509M Recombinant Mouse Asic1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Asic1-3072R Recombinant Rat Asic1, His-tagged E.Coli or Yeast His 526
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ASIC1 Related Articles

ASIC1 involved in several pathways and played different roles in them. We selected most pathways ASIC1 participated on our site, such as Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASIC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inflammatory mediator regulation of TRP channelsCYP2J2;CALML3;MAP2K3;BDKRB1;PIK3R5;TRPA1;ALOX12E;CYP2C39;PPP1CC

ASIC1 has several biochemical functions, for example, acid-sensing ion channel activity, ion gated channel activity, ligand-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ASIC1 itself. We selected most functions ASIC1 had, and list some proteins which have the same functions with ASIC1. You can find most of the proteins on our site.

Function Related Protein
acid-sensing ion channel activityASIC1A;ASIC1;ASIC1C;ACCN2;ASIC1B
ion gated channel activityASIC1;ACCN2
ligand-gated sodium channel activityACCN5;ASIC1A;ASIC1C;ACCN3;ASIC2;SCNN1D;ASIC3;ASIC4A;ASIC1B
protein bindingTHEG;HIST1H4J;WDTC1;TIGIT;ADPRH;SERPINA3;SPRY1;DUSP15;NXF1

ASIC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASIC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASIC1.

PICK1

Lin, LH; Jin, JW; et al. Acid-sensing ion channel 1 and nitric oxide synthase are in adjacent layers in the wall of rat and human cerebral arteries. JOURNAL OF CHEMICAL NEUROANATOMY 61-62:161-168(2014).
Dymowska, AK; Schultz, AG; et al. Acid-sensing ion channels are involved in epithelial Na+ uptake in the rainbow trout Oncorhynchus mykiss. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 307:C255-C265(2014).
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