ATP4A

  • Official Full Name

    ATPase, H+/K+ exchanging, alpha polypeptide
  • Synonyms

    ATP4A;ATPase, H+/K+ exchanging, alpha polypeptide;819;ENSG00000105675;ATP6A;19q13.1;potassium-transporting ATPase alpha chain 1;potassium-transporting ATPase alpha chain 1;proton pump;H(+)-K(+)-ATPase alpha subunit;gastric H,K-ATPase alpha subunit;gastric hydrogen-potassium ATPase;gastric H+/K+ ATPase alpha subunit;gastric H,K-ATPase catalytic subunit;gastric H(+)/K(+) ATPase subunit alpha;ATPase, H+/K+ transporting, alpha polypeptide;EC 3.6.3.10

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP4A-19H Recombinant Human ATP4A protein, His-tagged E.coli Human His 798-896 a.a.
Atp4a-20M Recombinant Mouse Atp4a protein, His/GST-tagged E.coli Mouse GST&His 786-1014 a.a.
ATP4A-465H Recombinant Human ATP4A Protein, His-tagged E.coli Human His Leu798~Gly896
ATP4a-3765H Recombinant Human ATP4a, His-tagged E.coli Human His 1035
ATP4A-8608HCL Recombinant Human ATP4A 293 Cell Lysate HEK293 Human Non
ATP4A-1297HF Recombinant Full Length Human ATP4A Protein In Vitro Cell Free System Human Full L. 1035 amino acids
ATP4A-3343H Recombinant Human ATP4A protein, His&Myc-tagged E.coli Human His&Myc 350-783aa

    Involved Pathway

    ATP4A involved in several pathways and played different roles in them. We selected most pathways ATP4A participated on our site, such as Oxidative phosphorylation,Collecting duct acid secretion,Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gastric acid secretion KCNK2,PRKCG,KCNJ15,HRH2,CALM4,PRKACG,CAMK2A,EZR,GNAI2,ATP4B
    Oxidative phosphorylation ATP6V1C1,ATP6V0E1,NDUFB11,NDUFA2,UQCRH,NDUFS2,NDUFB9,LHPP,SDHB,ATP6V1G1
    Collecting duct acid secretion ATP6V1F,TCIRG1,SLC12A7,ATP6V1A,CLCNKB,CA2,ATP6V0D2,ATP6V1C2,ATP6V1D,ATP6V0E

    Protein Function

    ATP4A has several biochemical functions, for example, ATP binding,hydrogen:potassium-exchanging ATPase activity,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP4A itself. We selected most functions ATP4A had, and list some proteins which have the same functions with ATP4A. You can find most of the proteins on our site.

    Function Related Protein
    sodium:potassium-exchanging ATPase activity FXYD2,ATP1A3,ATP1A1A.5,ATP1A4,ATP1A2A,ATP1A1A.3,ATP1A1,ATP1A1A.2,ATP1B2,ATP1A1A.4
    protein heterodimerization activity HIST1H3C,CD3E,NOTCH1,LTC4S,HIST1H3G,SLC51A,SRY,HIST1H4B,GM5506,SMAD2
    ATP binding DHX8,MYO15,PHKG1,MYH7B,FRK,MYH11,AK7A,IPPK,NME2B.2,NLRX1
    magnesium ion binding CERK,NUDT3,STK38L,SIK2,IDH3A,RRAGC,PIF1,IMPA1,COMTB,HPGDS
    hydrogen:potassium-exchanging ATPase activity ATP12A,ATP6V1E1B,ATP4B

    Interacting Protein

    ATP4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP4A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP4A.

    Resources

    References

    • Chobot, A; Wenzlau, J; et al. ATP4A autoimmunity and Helicobacter pylori infection in children with type 1 diabetes. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 177:598-602(2014).
    • Matsui, MS; Petris, MJ; et al. Omeprazole, a Gastric Proton Pump Inhibitor, Inhibits Melanogenesis by Blocking ATP7A Trafficking. JOURNAL OF INVESTIGATIVE DERMATOLOGY 135:834-841(2015).

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