ATP4A
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Official Full Name
ATPase, H+/K+ exchanging, alpha polypeptide -
Synonyms
ATP4A;ATPase, H+/K+ exchanging, alpha polypeptide;819;ENSG00000105675;ATP6A;19q13.1;potassium-transporting ATPase alpha chain 1;potassium-transporting ATPase alpha chain 1;proton pump;H(+)-K(+)-ATPase alpha subunit;gastric H,K-ATPase alpha subunit;gastric hydrogen-potassium ATPase;gastric H+/K+ ATPase alpha subunit;gastric H,K-ATPase catalytic subunit;gastric H(+)/K(+) ATPase subunit alpha;ATPase, H+/K+ transporting, alpha polypeptide;EC 3.6.3.10
Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATP4A-19H | Recombinant Human ATP4A protein, His-tagged | E.coli | Human | His | 798-896 a.a. | |
| Atp4a-20M | Recombinant Mouse Atp4a protein, His/GST-tagged | E.coli | Mouse | GST&His | 786-1014 a.a. | |
| ATP4A-465H | Recombinant Human ATP4A Protein, His-tagged | E.coli | Human | His | Leu798~Gly896 | |
| ATP4a-3765H | Recombinant Human ATP4a, His-tagged | E.coli | Human | His | 1035 |
|
| ATP4A-8608HCL | Recombinant Human ATP4A 293 Cell Lysate | HEK293 | Human | Non |
|
|
| ATP4A-1297HF | Recombinant Full Length Human ATP4A Protein | In Vitro Cell Free System | Human | Full L. 1035 amino acids |
|
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| ATP4A-3343H | Recombinant Human ATP4A protein, His&Myc-tagged | E.coli | Human | His&Myc | 350-783aa |
|
Involved Pathway
ATP4A involved in several pathways and played different roles in them. We selected most pathways ATP4A participated on our site, such as Oxidative phosphorylation,Collecting duct acid secretion,Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastric acid secretion | HRH2,KCNJ1,Car2,MYLK4,CAMK2B,ATP1B4,SST,ATP1B2,ATP4B,CAMK2G |
| Collecting duct acid secretion | ATP6V0A4,ATP6V1B1,SLC12A7,ATP4B,ATP6V0A1,ATP6V1B2,Car2,SLC4A1,ATP6V1F,ATP6V1E1 |
| Oxidative phosphorylation | COX5A,MT-ND4,NDUFS8A,NDUFC2-KCTD14,ATP6V0B,NDUFA13,ATP5IA,ATP6V1F,ATP6V0E1,NDUFS8B |
Protein Function
ATP4A has several biochemical functions, for example, ATP binding,hydrogen:potassium-exchanging ATPase activity,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP4A itself. We selected most functions ATP4A had, and list some proteins which have the same functions with ATP4A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| magnesium ion binding | PI4K2A,WEE2,ITPK1,IDH3B,PGP,DYRK2,ENO1B,NT5C1B,GSS,NUDT7 |
| ATP binding | CHD2,PIK3C2A,ATP1A1B,HK3,ULK1A,EPHB3A,ACTB2,TGFBR1A,ABCG2B,CDK19 |
| hydrogen:potassium-exchanging ATPase activity | ATP12A,ATP4B,ATP6V1E1B |
| sodium:potassium-exchanging ATPase activity | ATP1B3,ATP1A4,ATP1A2,ATP1A1B,ATP1A2A,ATP1A3B,ATP1A3,ATP1A3A,ATP1A1A.5,ATP1A1A.3 |
| protein heterodimerization activity | SOX4,HER5,HIST2H2AA4,POU5F3,CHRNB2,ODZ4,MLXIPL,TYR,TAL1,PDZD7 |
Interacting Protein
ATP4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP4A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP4A.
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References
- Chobot, A; Wenzlau, J; et al. ATP4A autoimmunity and Helicobacter pylori infection in children with type 1 diabetes. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 177:598-602(2014).
- Matsui, MS; Petris, MJ; et al. Omeprazole, a Gastric Proton Pump Inhibitor, Inhibits Melanogenesis by Blocking ATP7A Trafficking. JOURNAL OF INVESTIGATIVE DERMATOLOGY 135:834-841(2015).
