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ATP5D

  • Official Full Name

    ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit

  • Overview

    This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified.
  • Synonyms

    ATP5D; ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit; ATP synthase subunit delta, mitochondrial; F-ATPase delta subunit; mitochondrial ATP synthase, delta subunit; mitochondrial ATP synthase complex delta-subunit precusor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • SUMO
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP5D-10017H Recombinant Human ATP5D, GST-tagged E.coli GST 1-168a.a.
Human ATP5D-3572H Recombinant Human ATP5D protein, His-tagged E.coli His Ala23-Glu168
Human ATP5D-364H Recombinant Human ATP5D, His tagged E.coli N/A
Human ATP5D-27063TH Recombinant Human ATP5D, His-tagged E.coli His 146 amino acids
Human ATP5D-979H Recombinant Human ATP5D protein, His-tagged E.coli His
Human ATP5D-49HCL Recombinant Human ATP5D lysate HEK293 N/A
Human ATP5D-1338H Recombinant Human ATP5D Protein (23-168 aa), His-tagged Yeast His 23-168 aa
Human ATP5D-2993H Recombinant Human ATP5D Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ATP5D-5144H Recombinant Human ATP5D protein, GST-tagged E.coli GST 43-161aa
Human ATP5D-2569H Recombinant Human ATP5D protein, His-SUMO-tagged E.coli His-SUMO 23-168aa
Human ATP5D-5349H Recombinant Human ATP5D protein, His-Myc-tagged Yeast His/Myc 23-168aa
Human ATP5D-270H Recombinant Human ATP5D Protein, His-tagged E.coli N-His Met1-Glu168
Mouse Atp5d-1768M Recombinant Mouse Atp5d Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Atp5d-271M Recombinant Mouse Atp5d Protein, His-tagged E.coli N-His Met1-Glu168
Rat ATP5D-869R Recombinant Rat ATP5D Protein Mammalian Cell His
Rat Atp5d-3713R Recombinant Rat Atp5d, His-tagged E.Coli or Yeast His 168
Rat ATP5D-525R Recombinant Rat ATP5D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ATP5D-525R-B Recombinant Rat ATP5D Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATP5D-454R Recombinant Rhesus monkey ATP5D Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATP5D-283R Recombinant Rhesus Macaque ATP5D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ATP5D-283R-B Recombinant Rhesus Macaque ATP5D Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ATP5D-10333Z Recombinant Zebrafish ATP5D Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ATP5D involved in several pathways and played different roles in them. We selected most pathways ATP5D participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationNDUFS8;UQCRQ;COX8C;NDUFV2;NDUFS4;NDUFB1;COX7A2L;NDUFA9;ATP6V0A1
Metabolic pathwaysFAXDC2;BTD;PIGN;CYP21A2;CYP2C38;CBR1L;GGT5;CYP2R1;ALDOAA
Alzheimers diseaseATP5O;ADAM10;NDUFB11;NOS1;IL1B2;UQCRQ;ATP5G1;ATP5F1;NDUFB9
Parkinsons diseaseNDUFA7;UQCRC2;Casp3;UBE2J1;NDUFA11;NDUFB9;SDHD;MT-ATP6;ATP5J
Huntingtons diseaseTGM2;DCTN4;PLCB2;TBPL2;CREB5;ATP5F1;DNAH14;TRP53;NDUFV1

ATP5D has several biochemical functions, for example, contributes_to ADP binding, contributes_to ATP binding, contributes_to ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5D itself. We selected most functions ATP5D had, and list some proteins which have the same functions with ATP5D. You can find most of the proteins on our site.

Function Related Protein
contributes_to ADP bindingMSH6;ATP5D;MSH2
contributes_to ATP bindingSFRP5;MSH2;ATP1A2;ATP1B1;ATP5D;ABCG8;MSH6
contributes_to ATPase activityRUVBL2;MSH2;ATP5C1;ATP1B1;ATP5J2;ATP5B;RFC3;ABCA7;ATP5L
contributes_to proton-transporting ATP synthase activity, rotational mechanismATP5D;ATP5F1
proton-transporting ATPase activity, rotational mechanismATP6V1E2;ATPV0E2;ATP6V0CA;ATP5C1;ATP6V1AA;ATP6V0A1B;ATP6V1F;ATP5E;ATP6V1H
transmembrane transporter activitySLC2A3A;ATP5A1;AQP1;ATP5E;SLC22A16;SLC22A1;SLC22A7B.1;ATP5C1;SLC2A11L
transporter activityRBP1;AQP11;TMEM184A;AP3B2;PMP2;CDH17;SLC12A5B;SLC2A13B;CRABP2B

ATP5D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5D here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5D.

vpu; SGK1; RIPK2; EIF1B; ATP5F1; PSMD6; ATG5; TTN; FRMD3; ssrna_ug; Kcnk1; BLK; Atp5a1; P; SLC38A1

  • Q&As
  • Reviews

Q&As (6)

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In what diseases might ATP5D be a therapeutic target? 12/11/2021

ATP5D may serve as a potential therapeutic target in some neurological and metabolic diseases.

Are ATP5D mutations associated with nervous system diseases? 07/28/2021

Yes, mutations in the ATP5D gene are associated with certain neurological diseases such as multiple sclerosis, Parkinson's disease, etc.

What is the role of ATP5D protein in metabolic diseases? 06/27/2021

ATP5D protein may be related to the occurrence and progression of metabolic diseases such as obesity and diabetes.

How does ATP5D function in tumors? 10/01/2020

It may play a role in tumor cell metabolism and energy supply.

What is the biological function of ATP5D protein? 07/28/2020

ATP5D is a subunit of the F1 portion of the mitochondrial ATP synthase complex involved in mitochondrial energy production.

What are the regulatory mechanisms of ATP5D? 05/23/2019

The expression and function of ATP5D are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.

Customer Reviews (3)

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Reviews
08/01/2022

    Because the remarkable purity of ATP5D makes it a valuable tool for sensitive and accurate experiments.

    09/16/2020

      The remarkable repeatability of ATP5D makes it an invaluable tool for accurate and reproducible experiments.

      08/06/2019

        The protein's purity and consistency make it a top choice for Western-blot experiments.

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