ATP5J
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Official Full Name
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
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Overview
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11. -
Synonyms
ATP5J; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 , ATP5, ATP5A, ATPM; ATP synthase-coupling factor 6, mitochondrial; CF6; coupling factor 6; mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6; ATP synthase-coupling factor 6; ATP5; ATP5A; ATP5J_HUMAN; ATPase subunit F6; ATPM; F6; MS508; OTTHUMP00000096106; OTTHUMP00000096107; OTTHUMP00000096108; OTTHUMP00000096110; OTTHUMP00000096111; OTTHUMP00000096112; proliferation-inducing protein 36; mitochondrial ATP synthas;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bovine
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- E.Coli or Yeast
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
ATP5J involved in several pathways and played different roles in them. We selected most pathways ATP5J participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5J were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oxidative phosphorylation | ATP6V0B;SDHC;COX7B2;COX7A2L;UQCRC1;NDUFV2;NDUFA1;UQCRC2B;ATP6V0E2 |
| Metabolic pathways | APRT;MDH2;PGK2;FUT5;NDUFA5;MBOAT2B;LTA4H;SQLE;POLR3G |
| Alzheimers disease | CASP8;NDUFB2;Casp3;UQCRFS1;ATP2A2;ITPR2;APOE;SDHB;NAE1 |
| Parkinsons disease | NDUFS8;NDUFA8;MT-ND1;NDUFS6;SLC25A5;PRKACB;NDUFB8;NDUFA7;NDUFAB1 |
| Huntingtons disease | POLR2J2;POLR2I;DNAIC2;CASP9;NDUFB6;NDUFS1;TBPL1;Atp5g2;TGM2 |
ATP5J has several biochemical functions, for example, contributes_to ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5J itself. We selected most functions ATP5J had, and list some proteins which have the same functions with ATP5J. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to ATPase activity | ABCA7;ATP5O;MSH2;ABCG8;ATP5B;ATP5I;ATP5C1;ATP5L;ATP1A2 |
| hydrogen ion transmembrane transporter activity | ATP5IA;ATP6V0A1A;SLC36A3;ATP5I;ATP6V1F;Atp5k;ATP5G3A;ATP6V0E2;SLC11A2 |
| transmembrane transporter activity | ATP5J2;ATP5I;ATP5A1;SLC22A1;ATP5D;ATP5H;ATP5J;SLC22A17;AQP1 |
| transporter activity | ABCA1B;NUP88;AP2S1;SLC5A10;SCARB1;SLC25A38B;SLC23A1;CPNE1;DYF-1 |
ATP5J has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5J here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5J.
vpu; NFKB1; ATP5F1; RPS6KA3; MAPK6; GBA; RALA; TFEB; BLK; Atp5a1; CDC16; ITGB3BP; Cep131; Atp7a; P; SLC36A1
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