ATP6V1G3

  • Official Full Name

    ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

  • Overview

    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    ATP6V1G3;ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3;ATPase, H+ transporting, lysosomal 13kD, V1 subunit G isoform 3 , ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 3;V-type proton ATPase subunit G 3;ATP6G3;Vma10;MGC119810;MGC119813;MGC130213;MGC130214;V ATPase 13 kDa subunit 3;V ATPase subunit G 3;Vacuolar proton pump subunit G 3;V-ATPase G3 subunit;V-ATPase G subunit 3;V-ATPase subunit G 3;V-ATPase 13 kDa subunit 3;vacuolar proton pump G subunit 3;vacuolar proton pump, subunit G3;vacuolar ATP synthase subunit G 3;ATPase, H+ transporting, lysosomal (vacuolar proton pump) subunit G3

Recombinant Proteins

  • Human
  • Mouse
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP6V1G3-1011H Recombinant Human ATP6V1G3 protein, GST-tagged Wheat Germ Human GST
ATP6V1G3-2169M Recombinant Mouse ATP6V1G3 Protein Mammalian Cells Mouse His
ATP6V1G3-8574HCL Recombinant Human ATP6V1G3 293 Cell Lysate HEK293 Human Non
ATP6V1G3-8575HCL Recombinant Human ATP6V1G3 293 Cell Lysate HEK293 Human Non
ATP6V1G3-1333HF Recombinant Full Length Human ATP6V1G3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 118 amino acids
Atp6v1g3-1777M Recombinant Mouse Atp6v1g3 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
ATP6V1G3-883M Recombinant Mouse ATP6V1G3 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ATP6V1G3-883M-B Recombinant Mouse ATP6V1G3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ATP6V1G3 involved in several pathways and played different roles in them. We selected most pathways ATP6V1G3 participated on our site, such as Collecting duct acid secretion,Epithelial cell signaling in Helicobacter pylori infection,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V1G3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways SI,PPCDC,IDH3A,POLR2K,GPAA1,MTR,ACO2,CKB,HMGCS2,NDUFA3
    Oxidative phosphorylation Atp5k,PPA2,COX4I2,NDUFA9A,MT-ATP6,COX8C,ATP6V0A2,ATP6V1C1A,ATP5J,COX7A2
    Iron uptake and transport FTH1A,FLVCR1,CP,TFR1B,TFA,SLC46A1,MFSD7B,TCIRG1,LCN2,FTH1B
    Insulin receptor recycling TCIRG1
    Epithelial cell signaling in Helicobacter pylori infection CXCR2,MAPK11,JAM3,MAPK8,ATP6V1C1,LYN,CXCL1,MAPK13,ADAM17,ATP6V0D2
    Ion channel transport GABRR2A,CUTC,TRPM1B,TRPM1A,TPCN1,GSDMA2,ASPH,SCNN1D,ANO5,SLC9B2
    Collecting duct acid secretion ATP6V1F,ATP6V0E2,ATP6V1C2,ATP6V1C1,CA2,ATP6V1B2,ATP6V0A2,ATP6V1D,ATP4A,ATP4B
    Immune System WSB1,KLRG1,KIF15,BTR30,MB21D1,TRIM10,CTSD,XAF1,DYNC1I2,TNRC5

    Protein Function

    ATP6V1G3 has several biochemical functions, for example, ATPase binding,hydrogen-exporting ATPase activity, phosphorylative mechanism. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V1G3 itself. We selected most functions ATP6V1G3 had, and list some proteins which have the same functions with ATP6V1G3. You can find most of the proteins on our site.

    Function Related Protein
    ATPase binding ATP6V0A2,ATP1B3,ATP6V0A4,FXYD7,PLN,GRIN2A,FXYD3,FXYD4,LCK,ESR1
    hydrogen-exporting ATPase activity, phosphorylative mechanism ATP6V1E1,ATP6V1E2,ATP6V1C2,ATP6V1C1,ATP6V0D1,ATP6V1G1

    Interacting Protein

    ATP6V1G3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V1G3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V1G3.

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