ATPIF1

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ATPIF1

Official Full Name ATPase inhibitory factor 1
Background The ATPase inhibitor factor 1 (ATPIF1) gene encodes a mitochondrial ATPase inhibitor that limits ATP depletion when mitochondrial respiration is impaired. ATPIF1 becomes activated following a drop in pH, binding to beta-F1-ATPase, thereby inhibiting the h
Synonyms ATPIF1; ATPase inhibitory factor 1; ATPase inhibitor, mitochondrial; ATP synthase inhibitor protein; ATPase inhibitor protein; ATPI; ATPIP; IP; MGC1167; MGC8898; IF1; IF(1); inhibitor of F(1)F(o)-ATPase
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATPIF1-10061H Recombinant Human ATPIF1, GST-tagged E.coli GST
    Human ATPIF1-1025H Recombinant Human ATPIF1 protein, GST-tagged Wheat Germ GST
    Human ATPIF1-2517H Recombinant Human ATPase Inhibitory Factor 1, His-tagged E.coli His
    Human ATPIF1-8568HCL Recombinant Human ATPIF1 293 Cell Lysate HEK293 N/A
    Human ATPIF1-8569HCL Recombinant Human ATPIF1 293 Cell Lysate HEK293 N/A
    Mouse ATPIF1-2180M Recombinant Mouse ATPIF1 protein, His-tagged E.coli His
    Mouse ATPIF1-2185M Recombinant Mouse ATPIF1 Protein Mammalian Cell His
    Mouse Atpif1-677M Recombinant Mouse Atpif1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Atpif1-3764R Recombinant Rat Atpif1, GST-tagged E.Coli or Yeast GST
    Rat ATPIF1-898R Recombinant Rat ATPIF1 Protein Mammalian Cell His
    Rhesus Macaque ATPIF1-475R Recombinant Rhesus monkey ATPIF1 Protein, His-tagged Mammalian Cell His

    ATPIF1 involved in several pathways and played different roles in them. We selected most pathways ATPIF1 participated on our site, such as Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATPIF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Electron Transport Chain COX7A2; COX8A; COX6C; ATP5S; SLC25A27; NDUFC2-KCTD14; COX15; UCP2; ATPIF1; UCP3

    ATPIF1 has several biochemical functions, for example, NOT 5-formyltetrahydrofolate cyclo-ligase activity, ATPase binding, ATPase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATPIF1 itself. We selected most functions ATPIF1 had, and list some proteins which have the same functions with ATPIF1. You can find most of the proteins on our site.

    Function Related Protein
    NOT 5-formyltetrahydrofolate cyclo-ligase activity ATPIF1A; ATPIF1B; ATPIF1
    ATPase binding RALB; SLC26A9; NKAIN1; ATP6V0A1A; ATP6V0A1; GABARAPL2; NHP2L1; SVIP; ATP1B1; LCK
    ATPase inhibitor activity ATPIF1A; ATPIF1; PLN; ATPIF1B
    angiostatin binding ATPIF1
    calmodulin binding PDE1A; EPB41B; GM101; SLC14A2; CAMK1GB; CNGA2; CASK; MYH1; PHKA1; DCX
    enzyme inhibitor activity TXNIP; CSN2; SCG5; PPP1R12A; OAZ2A; NOTCH1; ARRB1; PLN; HSPBP1; APOV1
    protein homodimerization activity ANO2; RENBP; CADM3; PVR; CHEK2; CADM4; ZFP423; BCL2L1; TBC1D22A; LSM1

    ATPIF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATPIF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATPIF1.

    PIK3CA; GSK3B; CHD3; hflC; tdk; pelY; opuD; yibD; UBQLN4; YAP1; BLK; Atp5a1

    Freeman, KW; Bowman, BR; et al. Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling. FASEB JOURNAL 25:907-915(2011).
    Sanchez-Cenizo, L; Formentini, L; et al. Up-regulation of the ATPase Inhibitory Factor 1 (IF1) of the Mitochondrial H+-ATP Synthase in Human Tumors Mediates the Metabolic Shift of Cancer Cells to a Warburg Phenotype. JOURNAL OF BIOLOGICAL CHEMISTRY 285:25308-25313(2010).

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