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AUP1

  • Official Full Name

    ancient ubiquitous protein 1

  • Overview

    This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
  • Synonyms

    AUP1; ancient ubiquitous protein 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AUP1-1036H Recombinant Human AUP1 protein, GST-tagged Wheat Germ GST
Human AUP1-54HCL Recombinant Human AUP1 lysate HEK293 N/A
Human AUP1-528H Recombinant Human AUP1 Protein, His-tagged E.coli His Val201~Asp410
Human AUP1-1544HF Recombinant Full Length Human AUP1 Protein, GST-tagged In Vitro Cell Free System GST 410 amino acids
Human AUP1-0705H Recombinant Human AUP1 Protein (Val201-Asp410), His tagged E.coli His Val201-Asp410
Mouse Aup1529M Recombinant Mouse Aup1 Protein, His/GST-tagged E.coli His/GST Val201~Glu410
Rat Aup1-3450R Recombinant Rat Aup1, His-tagged E.Coli or Yeast His 410
Rat AUP1-903R Recombinant Rat AUP1 Protein Mammalian Cell His
Rat AUP1-559R Recombinant Rat AUP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AUP1-559R-B Recombinant Rat AUP1 Protein Pre-coupled Magnetic Beads HEK293
Mus musculus (Mouse) RFL35464MF Recombinant Full Length Mouse Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged E.coli expression system His Full Length (1-410)
Rattus norvegicus (Rat) RFL13665RF Recombinant Full Length Rat Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged E.coli expression system His Full Length (1-410)
Xenopus laevis (African clawed frog) RFL21079XF Recombinant Full Length Xenopus Laevis Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged E.coli expression system His Full Length (1-399)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL35936XF Recombinant Full Length Xenopus Tropicalis Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged E.coli expression system His Full Length (1-403)
Zebrafish AUP1-10088Z Recombinant Zebrafish AUP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

AUP1 involved in several pathways and played different roles in them. We selected most pathways AUP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AUP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AUP1 has several biochemical functions, for example, protein binding, ubiquitin binding, ubiquitin-protein transferase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AUP1 itself. We selected most functions AUP1 had, and list some proteins which have the same functions with AUP1. You can find most of the proteins on our site.

Function Related Protein
protein bindingMAP3K2;PEX6;TXLNG;SZL;CSNK2A1;ACYP2;ARMC8;SPP1;WASF2
ubiquitin bindingUSP16;USP25;UCHL3;USP5;VPS36;TOP2A;KCNS1;BRAP;TRP53INP2
ubiquitin-protein transferase activator activityAUP1;UBE2L3;FBXW7;CBX8;RING1

AUP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AUP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AUP1.

OPRM1; 5901994; ATG12; Oprd1; OPRK1; MAGEA6; UBE2G2; CLN3; ILK; NDN; BRF2; glgA; vanS; UBE2E3; RNF11; 1C; P

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