Creative BioMart to Join NIH Research Festival Biotech Vendor Exhibits 2024 | Sep. 25th, 2024 Learn More

B3GALTL

Official Full Name

beta 1,3-galactosyltransferase-like
Overview

The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).
Synonyms

B3GALTL; beta 1,3-galactosyltransferase-like; beta-1,3-glucosyltransferase; B3Glc T; B3GTL; B3GlcT; Beta 1,3 galactosyltransferase like; Beta 3 galactosyltransferase like; Beta3GlcT; Galactosyltransferase; GalT; beta 3-glycosyltransferase-like; beta-3-glycosyltransferase-like; UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like; Gal-T; B3Glc-T; beta3Glc-T;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Human Cell
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	B3GALTL-10098H	Recombinant Human B3GALTL, GST-tagged	E.coli	GST	199-498a.a.	$319 / 25μg
Human	B3GALTL-013H	Recombinant Human B3GALTL protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	B3GALTL-459H	Recombinant Human B3GALTL, His tagged	Human Cell	His&Fc	Ser29-Phe494	Inquiry
Human	B3GALTL-1103HCL	Recombinant Human B3GALTL cell lysate	Human Cell	Non		Inquiry
Human	B3GALTL-1716HF	Recombinant Full Length Human B3GALTL Protein, GST-tagged	In Vitro Cell Free System	GST	498 amino acids	Inquiry
Mouse	B3GALTL-2235M	Recombinant Mouse B3GALTL Protein	Mammalian Cell	His		Inquiry
Mouse	B3GALTL-926M	Recombinant Mouse B3GALTL Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	B3GALTL-926M-B	Recombinant Mouse B3GALTL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

B3GALTL involved in several pathways and played different roles in them. We selected most pathways B3GALTL participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GALTL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolism of proteins	MGAT4A;CCT6A;EIF2B1;CTSH;SPON1A;NSFB;EEF1A2;ADAMTSL4;NAPAB
O-glycosylation of TSR domain-containing proteins	ADAMTS1;SPON1B;THSD7A;THSD1;ADAMTS3;SSPO;ADAMTS10;ADAMTS8;B3GALTL
O-linked glycosylation	THSD1;THSD7A;MUCL1;ADAMTS18;SPON2;MUC12;ADAMTS4;ADAMTS1;MUC20
Other types of O-glycan biosynthesis	ST6GAL1;POFUT2;GLT25D1;MGAT5B;RFNG;OGT;B4GALT2;COLGALT2;B3GAT1A
Post-translational protein modification	GALNTL5;EIF5A2;ST6GAL2B;NEU4;TRAPPC5;MUC20;GCNT3;ADAMTS5;THSD7A

B3GALTL has several biochemical functions, for example, transferase activity, transferring glycosyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GALTL itself. We selected most functions B3GALTL had, and list some proteins which have the same functions with B3GALTL. You can find most of the proteins on our site.

Function	Related Protein
transferase activity, transferring glycosyl groups	B3GNT8;B3GALTLB;UGT1B1;UGT1B4;GALNT11;UGT5A2;UGT2B5;GLT1D1;PYGMB

B3GALTL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GALTL here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GALTL.

FGFR1OP; AK1; EMC2; SMC6

Research Area

Reis, LM; Semina, EV; et al. Genetics of anterior segment dysgenesis disorders. CURRENT OPINION IN OPHTHALMOLOGY 22:314-324(2011).

Aliferis, K; Marsal, C; et al. A novel nonsense B3GALTL mutation confirms Peters plus syndrome in a patient with multiple malformations and Peters anomaly. OPHTHALMIC GENETICS 31:205-208(2010).