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B4GALNT1

Official Full Name

beta-1,4-N-acetyl-galactosaminyl transferase 1
Overview

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively.
Synonyms

B4GALNT1; beta-1,4-N-acetyl-galactosaminyl transferase 1; GALGT, UDP Gal:betaGlcNAc beta 1,4 N acetylgalactosaminyltransferase transferase 1 , UDP N acetyl alpha D galactosamine:(N acetylneuraminyl) galactosylglucosylceramide N acetylgalactosaminyltransferase (GalNAc T); beta-1,4 N-acetylgalactosaminyltransferase 1; beta1 4GalNAc T; GD2 synthase; GM2 synthase; (N acetylneuraminyl) galactosylglucosylceramide; Beta 1 4 N acetyl galactosaminyl transferase 1; Beta 1 4 N acetylgalactosaminyltransferase 1; GALGT; GalNAc T; GALNACT; GM2/GD2 synthase; SIAT 2; SIAT2; UDP Gal:betaGlcNAc beta 1 4 N acetylgalactosaminyltransferase transferase 1; UDP N acetyl alpha D galactosamine:(N acetylneuraminyl) galactosylglucosylceramide N acetylgalactosaminyltransferase; GalNAc-T; beta1,4GalNAc-T; beta1-4GalNAc-T; GD2 synthase, GM2 synthase; (N-acetylneuraminyl)-galactosylglucosylceramide; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T);

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	B4GALNT1-026H	Recombinant Human B4GALNT1 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	B4GALNT1-2110HCL	Recombinant Human B4GALNT1 cell lysate		N/A		Inquiry
Human	B4GALNT1-1645HF	Recombinant Full Length Human B4GALNT1 Protein, GST-tagged	In Vitro Cell Free System	GST	328 amino acids	Inquiry
Rat	B4GALNT1-920R	Recombinant Rat B4GALNT1 Protein	Mammalian Cell	His		Inquiry
Rat	B4GALNT1-578R	Recombinant Rat B4GALNT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	B4GALNT1-578R-B	Recombinant Rat B4GALNT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

B4GALNT1 involved in several pathways and played different roles in them. We selected most pathways B4GALNT1 participated on our site, such as Glycosphingolipid biosynthesis - ganglio series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with B4GALNT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosphingolipid biosynthesis - ganglio series	ST6GALNAC4;ST8SIA5;B3GALT4;ST8SIA1;ST6GALNAC3;SLC33A1;ST6GALNAC5;HEXB;HEXA
Metabolic pathways	SAT1A.1;IMPDH1A;ATP5IA;ADH6;GALM;HSD3B1;TK2;MTMR6;DCXR

B4GALNT1 has several biochemical functions, for example, (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B4GALNT1 itself. We selected most functions B4GALNT1 had, and list some proteins which have the same functions with B4GALNT1. You can find most of the proteins on our site.

Function	Related Protein
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity

B4GALNT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B4GALNT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of B4GALNT1.