BCL2L14
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Official Full Name
BCL2-like 14 (apoptosis facilitator)
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Overview
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. -
Synonyms
BCL2L14; BCL2-like 14 (apoptosis facilitator); apoptosis facilitator Bcl-2-like protein 14; BCL G; BCLG; bcl2-L-14; apoptosis regulator BCL-G;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Myc
- DDK
- N
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
BCL2L14 involved in several pathways and played different roles in them. We selected most pathways BCL2L14 participated on our site, such as Direct p53 effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL2L14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Direct p53 effectors | DDX5;DUSP1;GDF15;PPM1J;ZNF385A;TADA2B;PCBP4;FOXA1;DDB2 |
BCL2L14 has several biochemical functions, for example, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL2L14 itself. We selected most functions BCL2L14 had, and list some proteins which have the same functions with BCL2L14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RBCK1;FANCD2;PDS5A;MAGEA11;TUBGCP2;UBC;VLDLR;CCT2;IGF2 |
| protein kinase binding | TUBB3;PPP1R12C;GRIN2A;AGTR1A;JTB;TRIM22;ADRA2A;LLGL1;FGFR1OP |
BCL2L14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL2L14 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL2L14.
MELK
Gene Family
Research Area
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